Core transcriptional regulatory circuitry in human embryonic stem cells LA Boyer, TI Lee, MF Cole, SE Johnstone, SS Levine, JP Zucker, ... cell 122 (6), 947-956, 2005 | 5593 | 2005 |
Control of developmental regulators by Polycomb in human embryonic stem cells TI Lee, RG Jenner, LA Boyer, MG Guenther, SS Levine, RM Kumar, ... Cell 125 (2), 301-313, 2006 | 2703 | 2006 |
A chromatin landmark and transcription initiation at most promoters in human cells MG Guenther, SS Levine, LA Boyer, R Jaenisch, RA Young Cell 130 (1), 77-88, 2007 | 2286 | 2007 |
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen CJ Phiel, F Zhang, EY Huang, MG Guenther, MA Lazar, PS Klein Journal of Biological Chemistry 276 (39), 36734-36741, 2001 | 2113 | 2001 |
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells A Marson, SS Levine, MF Cole, GM Frampton, T Brambrink, S Johnstone, ... cell 134 (3), 521-533, 2008 | 1775 | 2008 |
Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR W Fischle, F Dequiedt, MJ Hendzel, MG Guenther, MA Lazar, W Voelter, ... Molecular cell 9 (1), 45-57, 2002 | 936 | 2002 |
The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3 MG Guenther, ORR Barak, MA Lazar Molecular and cellular biology 21 (18), 6091-6101, 2001 | 774 | 2001 |
Master transcription factors determine cell-type-specific responses to TGF-β signaling AC Mullen, DA Orlando, JJ Newman, J Lovén, RM Kumar, S Bilodeau, ... Cell 147 (3), 565-576, 2011 | 676 | 2011 |
A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness MG Guenther, WS Lane, W Fischle, E Verdin, MA Lazar, R Shiekhattar Genes & development 14 (9), 1048-1057, 2000 | 588 | 2000 |
Chromatin structure and gene expression programs of human embryonic and induced pluripotent stem cells MG Guenther, GM Frampton, F Soldner, D Hockemeyer, M Mitalipova, ... Cell stem cell 7 (2), 249-257, 2010 | 565 | 2010 |
Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells AA Sigova, AC Mullen, B Molinie, S Gupta, DA Orlando, MG Guenther, ... Proceedings of the National Academy of Sciences 110 (8), 2876-2881, 2013 | 498 | 2013 |
Quantitative ChIP-Seq normalization reveals global modulation of the epigenome DA Orlando, MW Chen, VE Brown, S Solanki, YJ Choi, ER Olson, CC Fritz, ... Cell reports 9 (3), 1163-1170, 2014 | 488 | 2014 |
Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations CJ Lengner, AA Gimelbrant, JA Erwin, AW Cheng, MG Guenther, ... Cell 141 (5), 872-883, 2010 | 463 | 2010 |
Global and Hox-specific roles for the MLL1 methyltransferase MG Guenther, RG Jenner, B Chevalier, T Nakamura, CM Croce, ... Proceedings of the National Academy of Sciences 102 (24), 8603-8608, 2005 | 451 | 2005 |
Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway EY Huang, J Zhang, EA Miska, MG Guenther, T Kouzarides, MA Lazar Genes & development 14 (1), 45-54, 2000 | 404 | 2000 |
Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia MG Guenther, LN Lawton, T Rozovskaia, GM Frampton, SS Levine, ... Genes & development 22 (24), 3403-3408, 2008 | 300 | 2008 |
Proteasomal regulation of nuclear receptor corepressor-mediated repression J Zhang, MG Guenther, RW Carthew, MA Lazar Genes & development 12 (12), 1775-1780, 1998 | 279 | 1998 |
Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response GD Kao, WG McKenna, MG Guenther, RJ Muschel, MA Lazar, TJ Yen The Journal of cell biology 160 (7), 1017-1027, 2003 | 243 | 2003 |
A SANT motif in the SMRT corepressor interprets the histone code and promotes histone deacetylation J Yu, Y Li, T Ishizuka, MG Guenther, MA Lazar The EMBO journal, 2003 | 242 | 2003 |
Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy ME Beaulieu, T Jauset, D Massó-Vallés, S Martínez-Martín, P Rahl, ... Science translational medicine 11 (484), eaar5012, 2019 | 193 | 2019 |