Translocation of a gut pathobiont drives autoimmunity in mice and humans S Manfredo Vieira, M Hiltensperger, V Kumar, D Zegarra-Ruiz, C Dehner, ... Science 359 (6380), 1156-1161, 2018 | 762 | 2018 |
Host–microbiota interactions in immune-mediated diseases WE Ruff, TM Greiling, MA Kriegel Nature Reviews Microbiology 18 (9), 521-538, 2020 | 350 | 2020 |
Commensal orthologs of the human autoantigen Ro60 as triggers of autoimmunity in lupus TM Greiling, C Dehner, X Chen, K Hughes, AJ Iñiguez, M Boccitto, ... Science Translational Medicine 10 (434), eaan2306, 2018 | 284 | 2018 |
A diet-sensitive commensal lactobacillus strain mediates TLR7-dependent systemic autoimmunity DF Zegarra-Ruiz, A El Beidaq, AJ Iñiguez, ML Di Ricco, SM Vieira, ... Cell host & microbe 25 (1), 113-127. e6, 2019 | 261 | 2019 |
PD-1 on dendritic cells impedes innate immunity against bacterial infection S Yao, S Wang, Y Zhu, L Luo, G Zhu, S Flies, H Xu, W Ruff, M Broadwater, ... Blood, The Journal of the American Society of Hematology 113 (23), 5811-5818, 2009 | 249 | 2009 |
B7-H5 costimulates human T cells via CD28H Y Zhu, S Yao, BP Iliopoulou, X Han, MM Augustine, H Xu, RT Phennicie, ... Nature communications 4 (1), 1-12, 2013 | 200 | 2013 |
B7-h2 is a costimulatory ligand for CD28 in human S Yao, Y Zhu, G Zhu, M Augustine, L Zheng, DJ Goode, M Broadwater, ... Immunity 34 (5), 729-740, 2011 | 193 | 2011 |
Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19 A Unterman, TS Sumida, N Nouri, X Yan, AY Zhao, V Gasque, JC Schupp, ... Nature communications 13 (1), 440, 2022 | 152 | 2022 |
Autoimmune host–microbiota interactions at barrier sites and beyond WE Ruff, MA Kriegel Trends in molecular medicine 21 (4), 233-244, 2015 | 139 | 2015 |
Pathogenic autoreactive T and B cells cross-react with mimotopes expressed by a common human gut commensal to trigger autoimmunity WE Ruff, C Dehner, WJ Kim, O Pagovich, CL Aguiar, TY Andrew, AS Roth, ... Cell host & microbe 26 (1), 100-113. e8, 2019 | 136 | 2019 |
Glucose-6–phosphatase is a key metabolic regulator of glioblastoma invasion S Abbadi, JJ Rodarte, A Abutaleb, E Lavell, CL Smith, W Ruff, J Schiller, ... Molecular Cancer Research 12 (11), 1547-1559, 2014 | 82 | 2014 |
The role of the gut microbiota in the pathogenesis of antiphospholipid syndrome WE Ruff, SM Vieira, MA Kriegel Current rheumatology reports 17, 1-10, 2015 | 53 | 2015 |
Neuron-specific SALM5 limits inflammation in the CNS via its interaction with HVEM Y Zhu, S Yao, MM Augustine, H Xu, J Wang, J Sun, M Broadwater, W Ruff, ... Science advances 2 (4), e1500637, 2016 | 50 | 2016 |
B7-H3 promotes pathogenesis of autoimmune disease and inflammation by regulating the activity of different T cell subsets L Luo, G Zhu, H Xu, S Yao, G Zhou, Y Zhu, K Tamada, L Huang, AD Flies, ... PloS one 10 (6), e0130126, 2015 | 50 | 2015 |
CXCR3+ T cells in multiple sclerosis correlate with reduced diversity of the gut microbiome SN Choileáin, M Kleinewietfeld, K Raddassi, DA Hafler, WE Ruff, ... Journal of translational autoimmunity 3, 100032, 2020 | 44 | 2020 |
Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: results from the IMPACC study A Ozonoff, J Schaenman, ND Jayavelu, CE Milliren, CS Calfee, CB Cairns, ... EBioMedicine 83, 2022 | 41 | 2022 |
Influence of immunomodulatory drugs on the gut microbiota I Cohen, WE Ruff, EE Longbrake Translational Research 233, 144-161, 2021 | 19 | 2021 |
Impaired TIGIT expression on B cells drives circulating follicular helper T cell expansion in multiple sclerosis H Asashima, PP Axisa, THG Pham, EE Longbrake, WE Ruff, N Lele, ... The Journal of Clinical Investigation 132 (20), 2022 | 17 | 2022 |
PD-1highCXCR5–CD4+ peripheral helper T cells promote CXCR3+ plasmablasts in human acute viral infection H Asashima, S Mohanty, M Comi, WE Ruff, KB Hoehn, P Wong, J Klein, ... Cell Reports 42 (1), 2023 | 16 | 2023 |
Expression of the pituitary stem/progenitor marker GFRα2 in human pituitary adenomas and normal pituitary N Mathioudakis, R Sundaresh, A Larsen, W Ruff, J Schiller, ... Pituitary 18, 31-41, 2015 | 15 | 2015 |