Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence L Litovchick, S Sadasivam, L Florens, X Zhu, SK Swanson, S Velmurugan, ... Molecular cell 26 (4), 539-551, 2007 | 469 | 2007 |
Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins O Rozenblatt-Rosen, RC Deo, M Padi, G Adelmant, MA Calderwood, ... Nature 487 (7408), 491-495, 2012 | 428 | 2012 |
DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly L Litovchick, LA Florens, SK Swanson, MP Washburn, JA DeCaprio Genes & development 25 (8), 801-813, 2011 | 320 | 2011 |
A kinase shRNA screen links LATS2 and the pRB tumor suppressor K Tschöp, AR Conery, L Litovchick, JA DeCaprio, J Settleman, E Harlow, ... Genes & development 25 (8), 814-830, 2011 | 147 | 2011 |
The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes GA Müller, M Quaas, M Schümann, E Krause, M Padi, M Fischer, ... Nucleic acids research 40 (4), 1561-1578, 2012 | 123 | 2012 |
Structural mechanisms of DREAM complex assembly and regulation KZ Guiley, TJ Liban, JG Felthousen, P Ramanan, L Litovchick, SM Rubin Genes & development 29 (9), 961-974, 2015 | 116 | 2015 |
The DREAM complex mediates GIST cell quiescence and is a novel therapeutic target to enhance imatinib-induced apoptosis S Boichuk, JA Parry, KR Makielski, L Litovchick, JL Baron, JP Zewe, ... Cancer research 73 (16), 5120-5129, 2013 | 102 | 2013 |
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation ML Beshiri, KB Holmes, WF Richter, S Hess, AB Islam, Q Yan, L Plante, ... Proceedings of the National Academy of Sciences 109 (45), 18499-18504, 2012 | 89 | 2012 |
Nucleocytoplasmic shuttling of p130/RBL2: novel regulatory mechanism A Chestukhin, L Litovchick, K Rudich, JA DeCaprio Molecular and cellular biology, 2002 | 80 | 2002 |
The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb AN Iness, J Felthousen, V Ananthapadmanabhan, F Sesay, S Saini, ... Oncogene 38 (7), 1080-1092, 2019 | 79 | 2019 |
PP2A-mediated regulation of Ras signaling in G2 is essential for stable quiescence and normal G1 length N Naetar, V Soundarapandian, L Litovchick, KL Goguen, AA Sablina, ... Molecular cell 54 (6), 932-945, 2014 | 78 | 2014 |
Identification of FAM111A as an SV40 host range restriction and adenovirus helper factor DA Fine, O Rozenblatt-Rosen, M Padi, A Korkhin, RL James, G Adelmant, ... Public Library of Science 8 (10), e1002949, 2012 | 76 | 2012 |
Glycogen synthase kinase 3 phosphorylates RBL2/p130 during quiescence L Litovchick, A Chestukhin, JA DeCaprio Molecular and cellular biology, 2004 | 74 | 2004 |
Phosphorylation of the retinoblastoma-related protein p130 in growth-arrested cells AJ Canhoto, A Chestukhin, L Litovchick, JA DeCaprio Oncogene 19 (44), 5116-5122, 2000 | 67 | 2000 |
Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promoters AH Marceau, JG Felthousen, PD Goetsch, AN Iness, HW Lee, SM Tripathi, ... Nature communications 7 (1), 12301, 2016 | 63 | 2016 |
A selective interaction between OS-9 and the carboxyl-terminal tail of meprin β L Litovchick, E Friedmann, S Shaltiel Journal of Biological Chemistry 277 (37), 34413-34423, 2002 | 62 | 2002 |
Unveiling the substrate specificity of meprin β on the basis of the site in protein kinase A cleaved by the kinase splitting membranal proteinase A Chestukhin, L Litovchick, K Muradov, M Batkin, S Shaltiel Journal of Biological Chemistry 272 (6), 3153-3160, 1997 | 58 | 1997 |
PAF remodels the DREAM complex to bypass cell quiescence and promote lung tumorigenesis MJ Kim, C Cervantes, YS Jung, X Zhang, J Zhang, SH Lee, S Jun, ... Molecular cell 81 (8), 1698-1714. e6, 2021 | 45 | 2021 |
The cleavage of protein kinase A by the kinase-splitting membranal proteinase is reproduced by meprin β A Chestukhin, K Muradov, L Litovchick, S Shaltiel Journal of Biological Chemistry 271 (47), 30272-30280, 1996 | 42 | 1996 |
DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169 V R. Menon, V Ananthapadmanabhan, S Swanson, S Saini, F Sesay, ... Cell Cycle 18 (5), 531-551, 2019 | 40 | 2019 |