Pathological role of a point mutation (T315I) in BCR‐ABL1 protein—a computational insight V Rajendran, C Gopalakrishnan, R Sethumadhavan Journal of cellular biochemistry 119 (1), 918-925, 2018 | 115 | 2018 |
Alpha-synuclein aggregation in Parkinson's disease E Srinivasan, G Chandrasekhar, P Chandrasekar, K Anbarasu, ... Frontiers in medicine 8, 736978, 2021 | 97 | 2021 |
Impact of point mutation P29S in RAC1 on tumorigenesis V Rajendran, C Gopalakrishnan, R Purohit Tumor Biology 37, 15293-15304, 2016 | 93 | 2016 |
Inhibitory effect of brazilein on tyrosinase and melanin synthesis: Kinetics and in silico approach. SR Hridya H, Amrita A, Sankari M, George Priya Doss C, Gopalakrishnan M ... International Journal of Biological Macromolecules 81, 228-34, 2015 | 58 | 2015 |
Biophysical aspect of phosphatidylinositol 3-kinase and role of oncogenic mutants (E542K & E545K) N Kalsi, C Gopalakrishnan, V Rajendran, R Purohit Journal of Biomolecular Structure and Dynamics 34 (12), 2711-2721, 2016 | 34 | 2016 |
Mutations in microRNA binding sites of CEP genes involved in cancer C Gopalakrishnan, B Kamaraj, R Purohit Cell Biochemistry and Biophysics 70, 1933-1942, 2014 | 34 | 2014 |
Network analysis of transcriptomics data for the prediction and prioritization of membrane-associated biomarkers for idiopathic pulmonary fibrosis (IPF) by bioinformatics approach S Mishra, MI Shah, SU Kumar, DT Kumar, C Gopalakrishnan, ... Advances in protein chemistry and structural biology 123, 241-273, 2021 | 31 | 2021 |
In silico analysis of miRNA-mediated gene regulation in OCA and OA genes B Kamaraj, C Gopalakrishnan, R Purohit Cell biochemistry and biophysics 70, 1923-1932, 2014 | 28 | 2014 |
Single nucleotide polymorphisms in microRNA binding sites: implications in colorectal cancer P Bhaumik, C Gopalakrishnan, B Kamaraj, R Purohit The Scientific World Journal 2014, 2014 | 27 | 2014 |
Gene regulatory network rewiring in the immune cells associated with cancer P Han, C Gopalakrishnan, H Yu, E Wang Genes 8 (11), 308, 2017 | 20 | 2017 |
Biophysical aspect of huntingtin protein during polyQ: An in silico insight C Gopalakrishnan, S Jethi, N Kalsi, R Purohit Cell Biochemistry and Biophysics 74, 129-139, 2016 | 19 | 2016 |
Computational investigation of molecular mechanism and neuropathological implications in Huntington disease C Gopalakrishnan, N Kalsi, S Jethi, R Purohit Molecular and cellular biochemistry 409, 1-11, 2015 | 13 | 2015 |
Interactions of Caenorhabditis elegans β-tubulins with the microtubule inhibitor and anthelmintic drug albendazole LM Pallotto, CM Dilks, YJ Park, RB Smit, BT Lu, C Gopalakrishnan, ... Genetics 221 (4), iyac093, 2022 | 11 | 2022 |
Prioritization of SNPs in y+ LAT‐1 culpable of Lysinuric protein intolerance and their mutational impacts using protein‐protein docking and molecular dynamics simulation studies C Gopalakrishnan, AM Al‐Subaie, N N, HY Yeh, IA Tayubi, B Kamaraj Journal of Cellular Biochemistry 120 (10), 18496-18508, 2019 | 10 | 2019 |
Probing the polyphenolic flavonoid, morin as a highly efficacious inhibitor against amyloid (A4V) mutant SOD1 in fatal amyotrophic lateral sclerosis E Srinivasan, G Chandrasekhar, R Rajasekaran Archives of Biochemistry and Biophysics 727, 109318, 2022 | 7 | 2022 |
Hydrophobic residues confer the helicity and membrane permeability of ocellatin-1 antimicrobial peptide scaffold towards therapeutics P Chandra Sekar, G Chandrasekhar, R Rajasekaran International Journal of Peptide Research and Therapeutics 27, 2459-2470, 2021 | 6 | 2021 |
Probing the competitive inhibitor efficacy of frog-skin alpha helical AMPs identified against ACE2 binding to SARS-CoV-2 S1 spike protein as therapeutic scaffold to prevent … PC Sekar, E Srinivasan, G Chandrasekhar, DM Paul, G Sanjay, S Surya, ... Journal of molecular modeling 28 (5), 128, 2022 | 4 | 2022 |
Decoding conformational imprint of convoluted molecular interactions between prenylflavonoids and aggregated amyloid-Beta42 peptide causing Alzheimer’s disease E Srinivasan, G Chandrasekhar, P Chandrasekar, K Anbarasu, ... Frontiers in Chemistry 9, 753146, 2021 | 4 | 2021 |
Investigating the pernicious effects of heparan sulfate in serum amyloid A1 protein aggregation: a structural bioinformatics approach G Chandrasekhar, R Rajasekaran Journal of Biomolecular Structure and Dynamics 40 (4), 1776-1790, 2022 | 3 | 2022 |
Computer aided therapeutic tripeptide design, in alleviating the pathogenic proclivities of nocuous α-synuclein fibrils G Chandrasekhar, E Srinivasan, S Nandhini, G Pravallika, G Sanjay, ... Journal of Biomolecular Structure and Dynamics, 1-12, 2023 | 2 | 2023 |