| Exosome-delivered microRNAs modulate the inflammatory response to endotoxin M Alexander, R Hu, MC Runtsch, DA Kagele, TL Mosbruger, ... Nature communications 6 (1), 7321, 2015 | 743 | 2015 |
| Ketogenic diets alter the gut microbiome resulting in decreased intestinal Th17 cells QY Ang, M Alexander, JC Newman, Y Tian, J Cai, V Upadhyay, ... Cell 181 (6), 1263-1275. e16, 2020 | 379 | 2020 |
| miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation R Hu, DA Kagele, TB Huffaker, MC Runtsch, M Alexander, J Liu, E Bake, ... Immunity 41 (4), 605-619, 2014 | 172 | 2014 |
| Human gut bacterial metabolism drives Th17 activation and colitis Margaret Alexander, Qi Yan Ang, Renuka R. Nayak, Annamarie E. Bustion ... Cell Host & Microbe 30 (1), 17 - 30.e9, 2022 | 118 | 2022 |
| Precision medicine goes microscopic: engineering the microbiome to improve drug outcomes KN Lam, M Alexander, PJ Turnbaugh Cell host & microbe 26 (1), 22-34, 2019 | 106 | 2019 |
| Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome KN Lam, P Spanogiannopoulos, P Soto-Perez, M Alexander, MJ Nalley, ... Cell Reports 37 (5), 2021 | 97 | 2021 |
| The pretreatment gut microbiome is associated with lack of response to methotrexate in new‐onset rheumatoid arthritis A Artacho, S Isaac, R Nayak, A Flor‐Duro, M Alexander, I Koo, ... Arthritis & rheumatology 73 (6), 931-942, 2021 | 97 | 2021 |
| Deconstructing mechanisms of diet-microbiome-immune interactions M Alexander, PJ Turnbaugh Immunity 53 (2), 264-276, 2020 | 93 | 2020 |
| Methotrexate impacts conserved pathways in diverse human gut bacteria leading to decreased host immune activation RR Nayak, M Alexander, I Deshpande, K Stapleton-Gray, B Rimal, ... Cell host & microbe 29 (3), 362-377. e11, 2021 | 92 | 2021 |
| Rab27-dependent exosome production inhibits chronic inflammation and enables acute responses to inflammatory stimuli M Alexander, AG Ramstead, KM Bauer, SH Lee, MC Runtsch, J Wallace, ... The Journal of Immunology 199 (10), 3559-3570, 2017 | 85 | 2017 |
| Antitumor immunity is defective in T cell–specific microRNA-155–deficient mice and is rescued by immune checkpoint blockade TB Huffaker, SH Lee, WW Tang, JA Wallace, M Alexander, MC Runtsch, ... Journal of Biological Chemistry 292 (45), 18530-18541, 2017 | 73 | 2017 |
| Defective apical extrusion signaling contributes to aggressive tumor hallmarks Y Gu, J Shea, G Slattum, MA Firpo, M Alexander, SJ Mulvihill, ... Elife 4, e04069, 2015 | 67 | 2015 |
| miR-155 promotes FLT3-ITD–induced myeloproliferative disease through inhibition of the interferon response JA Wallace, DA Kagele, AM Eiring, CN Kim, R Hu, MC Runtsch, ... Blood, The Journal of the American Society of Hematology 129 (23), 3074-3086, 2017 | 64 | 2017 |
| MicroRNA-146a constrains multiple parameters of intestinal immunity and increases susceptibility to DSS colitis MC Runtsch, R Hu, M Alexander, J Wallace, D Kagele, C Petersen, ... Oncotarget 6 (30), 28556, 2015 | 61 | 2015 |
| Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease MC Runtsch, MC Nelson, SH Lee, W Voth, M Alexander, R Hu, J Wallace, ... PLoS genetics 15 (2), e1007970, 2019 | 55 | 2019 |
| Noncoding RNAs and chronic inflammation: Micro‐managing the fire within M Alexander, RM O'Connell BioEssays 37 (9), 1005-1015, 2015 | 31 | 2015 |
| Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators X Dong, BGH Guthrie, M Alexander, C Noecker, L Ramirez, NR Glasser, ... Nature Communications 13 (1), 7624, 2022 | 18 | 2022 |
| Perturbation of the human gut microbiome by a non-antibiotic drug contributes to the resolution of autoimmune disease RR Nayak, M Alexander, K Stapleton-Grey, C Ubeda, JU Scher, ... Biorxiv, 600155, 2019 | 16 | 2019 |
| Systems biology elucidates the distinctive metabolic niche filled by the human gut microbe Eggerthella lenta C Noecker, J Sanchez, JE Bisanz, V Escalante, M Alexander, K Trepka, ... PLoS biology 21 (5), e3002125, 2023 | 12 | 2023 |
| A diet-dependent enzyme from the human gut microbiome promotes Th17 cell accumulation and colitis M Alexander, QY Ang, RR Nayak, AE Bustion, V Upadhyay, KS Pollard, ... bioRxiv, 766899, 2020 | 6 | 2020 |
