Engineered endolysin-based “Artilysins” to combat multidrug-resistant gram-negative pathogens Y Briers, M Walmagh, V Van Puyenbroeck, A Cornelissen, W Cenens, ... MBio 5 (4), 10.1128/mbio. 01379-14, 2014 | 354 | 2014 |
Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process A Latka, B Maciejewska, G Majkowska-Skrobek, Y Briers, Z Drulis-Kawa Applied microbiology and biotechnology 101, 3103-3119, 2017 | 290 | 2017 |
Muralytic activity and modular structure of the endolysins of Pseudomonas aeruginosa bacteriophages φKZ and EL Y Briers, G Volckaert, A Cornelissen, S Lagaert, CW Michiels, K Hertveldt, ... Molecular microbiology 65 (5), 1334-1344, 2007 | 243 | 2007 |
Art-175 is a highly efficient antibacterial against multidrug-resistant strains and persisters of Pseudomonas aeruginosa Y Briers, M Walmagh, B Grymonprez, M Biebl, JP Pirnay, V Defraine, ... Antimicrobial agents and chemotherapy 58 (7), 3774-3784, 2014 | 215 | 2014 |
Breaking barriers: expansion of the use of endolysins as novel antibacterials against Gram-negative bacteria Y Briers, R Lavigne Future microbiology 10 (3), 377-390, 2015 | 207 | 2015 |
Synthetic biology of modular endolysins H Gerstmans, B Criel, Y Briers Biotechnology advances 36 (3), 624-640, 2018 | 165 | 2018 |
Use of bacteriophage endolysin EL188 and outer membrane permeabilizers against Pseudomonas aeruginosa Y Briers, M Walmagh, R Lavigne Journal of applied microbiology 110 (3), 778-785, 2011 | 165 | 2011 |
The preclinical and clinical progress of bacteriophages and their lytic enzymes: the parts are easier than the whole K Abdelkader, H Gerstmans, A Saafan, T Dishisha, Y Briers Viruses 11 (2), 96, 2019 | 148 | 2019 |
Characterization of Modular Bacteriophage Endolysins from Myoviridae Phages OBP, 201φ2-1 and PVP-SE1 M Walmagh, Y Briers, SB Santos, J Azeredo, R Lavigne PLoS One 7 (5), e36991, 2012 | 147 | 2012 |
Efficacy of artilysin Art-175 against resistant and persistent Acinetobacter baumannii V Defraine, J Schuermans, B Grymonprez, SK Govers, A Aertsen, ... Antimicrobial agents and chemotherapy 60 (6), 3480-3488, 2016 | 139 | 2016 |
From endolysins to Artilysin® s: novel enzyme-based approaches to kill drug-resistant bacteria H Gerstmans, L Rodríguez-Rubio, R Lavigne, Y Briers Biochemical Society Transactions 44 (1), 123-128, 2016 | 119 | 2016 |
Identification and characterization of a highly thermostable bacteriophage lysozyme R Lavigne, Y Briers, K Hertveldt, J Robben, G Volckaert Cellular and Molecular Life Sciences CMLS 61, 2753-2759, 2004 | 116 | 2004 |
Characterization of Novel Bacteriophages for Biocontrol of Bacterial Blight in Leek Caused by Pseudomonas syringae pv. porri S Rombouts, A Volckaert, S Venneman, B Declercq, D Vandenheuvel, ... Frontiers in microbiology 7, 279, 2016 | 112 | 2016 |
Characterization of five novel endolysins from Gram-negative infecting bacteriophages M Walmagh, B Boczkowska, B Grymonprez, Y Briers, Z Drulis-Kawa, ... Applied microbiology and biotechnology 97, 4369-4375, 2013 | 112 | 2013 |
The high-affinity peptidoglycan binding domain of Pseudomonas phage endolysin KZ144 Y Briers, M Schmelcher, MJ Loessner, J Hendrix, Y Engelborghs, ... Biochemical and biophysical research communications 383 (2), 187-191, 2009 | 110 | 2009 |
Role of the pre-neck appendage protein (Dpo7) from phage vB_SepiS-phiIPLA7 as an anti-biofilm agent in staphylococcal species D Gutiérrez, Y Briers, L Rodríguez-Rubio, B Martínez, A Rodríguez, ... Frontiers in microbiology 6, 167086, 2015 | 108 | 2015 |
Phage-borne depolymerases decrease Klebsiella pneumoniae resistance to innate defense mechanisms G Majkowska-Skrobek, A Latka, R Berisio, F Squeglia, B Maciejewska, ... Frontiers in Microbiology 9, 419180, 2018 | 103 | 2018 |
Genome sequence of Listeria monocytogenes Scott A, a clinical isolate from a food-borne listeriosis outbreak Y Briers, J Klumpp, M Schuppler, MJ Loessner Journal of bacteriology 193 (16), 4284-4285, 2011 | 103 | 2011 |
Enzybiotics: Enzyme-based antibacterials as therapeutics D Dams, Y Briers Therapeutic enzymes: Function and clinical implications, 233-253, 2019 | 100 | 2019 |
A standardized approach for accurate quantification of murein hydrolase activity in high-throughput assays Y Briers, R Lavigne, G Volckaert, K Hertveldt Journal of biochemical and biophysical methods 70 (3), 531-533, 2007 | 98 | 2007 |