A global reference for human genetic variation 1000 Genomes Project Consortium Nature 526 (7571), 68, 2015 | 15087 | 2015 |
An integrated map of genetic variation from 1,092 human genomes 1000 Genomes Project Consortium Nature 491 (7422), 56, 2012 | 8300 | 2012 |
Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes R Cristescu, J Lee, M Nebozhyn, KM Kim, JC Ting, SS Wong, J Liu, ... Nature medicine 21 (5), 449-456, 2015 | 1895 | 2015 |
Sequencing of 50 human exomes reveals adaptation to high altitude X Yi, Y Liang, E Huerta-Sanchez, X Jin, ZXP Cuo, JE Pool, X Xu, H Jiang, ... science 329 (5987), 75-78, 2010 | 1740 | 2010 |
The sequence and de novo assembly of the giant panda genome R Li, W Fan, G Tian, H Zhu, L He, J Cai, Q Huang, Q Cai, B Li, Y Bai, ... Nature 463 (7279), 311-317, 2010 | 1377 | 2010 |
Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma WK Sung, H Zheng, S Li, R Chen, X Liu, Y Li, NP Lee, WH Lee, ... Nature genetics 44 (7), 765-769, 2012 | 990 | 2012 |
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people MR Nelson, D Wegmann, MG Ehm, D Kessner, P St. Jean, C Verzilli, ... Science 337 (6090), 100-104, 2012 | 809 | 2012 |
Single-cell exome sequencing reveals single-nucleotide mutation characteristics of a kidney tumor X Xu, Y Hou, X Yin, L Bao, A Tang, L Song, F Li, S Tsang, K Wu, H Wu, ... Cell 148 (5), 886-895, 2012 | 730 | 2012 |
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma Z Kan, H Zheng, X Liu, S Li, TD Barber, Z Gong, H Gao, K Hao, ... Genome research 23 (9), 1422-1433, 2013 | 589 | 2013 |
Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism Z Hu, D Zhu, W Wang, W Li, W Jia, X Zeng, W Ding, L Yu, X Wang, ... Nature genetics 47 (2), 158-163, 2015 | 511 | 2015 |
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants Y Li, N Vinckenbosch, G Tian, E Huerta-Sanchez, T Jiang, H Jiang, ... Nature genetics 42 (11), 969-972, 2010 | 375 | 2010 |
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma G Guo, Y Gui, S Gao, A Tang, X Hu, Y Huang, W Jia, Z Li, M He, L Sun, ... Nature genetics 44 (1), 17-19, 2012 | 368 | 2012 |
Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences GD Poznik, Y Xue, FL Mendez, TF Willems, A Massaia, MA Wilson Sayres, ... Nature genetics 48 (6), 593-599, 2016 | 358 | 2016 |
Genomic and oncogenic preference of HBV integration in hepatocellular carcinoma LH Zhao, X Liu, HX Yan, WY Li, X Zeng, Y Yang, J Zhao, SP Liu, ... Nature communications 7 (1), 12992, 2016 | 354 | 2016 |
Rapid detection of structural variation in a human genome using nanochannel-based genome mapping technology H Cao, AR Hastie, D Cao, ET Lam, Y Sun, H Huang, X Liu, L Lin, ... GigaScience 3 (1), 2047-217X-3-34, 2014 | 210 | 2014 |
BIPES, a cost-effective high-throughput method for assessing microbial diversity HW Zhou, DF Li, NFY Tam, XT Jiang, H Zhang, HF Sheng, J Qin, X Liu, ... The ISME journal 5 (4), 741-749, 2011 | 207 | 2011 |
Deep sequencing of the MHC region in the Chinese population contributes to studies of complex disease F Zhou, H Cao, X Zuo, T Zhang, X Zhang, X Liu, R Xu, G Chen, Y Zhang, ... Nature genetics 48 (7), 740-746, 2016 | 202 | 2016 |
Efficient and unique cobarcoding of second-generation sequencing reads from long DNA molecules enabling cost-effective and accurate sequencing, haplotyping, and de novo assembly O Wang, R Chin, X Cheng, MKY Wu, Q Mao, J Tang, Y Sun, E Anderson, ... Genome research 29 (5), 798-808, 2019 | 197 | 2019 |
Novel loci and pathways significantly associated with longevity YI Zeng, C Nie, J Min, X Liu, M Li, H Chen, H Xu, M Wang, T Ni, Y Li, ... Scientific reports 6 (1), 21243, 2016 | 184 | 2016 |
Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies D Ellinghaus, H Zhang, S Zeissig, S Lipinski, A Till, T Jiang, B Stade, ... Gastroenterology 145 (2), 339-347, 2013 | 182 | 2013 |