TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8+ T cell exhaustion H Seo, J Chen, E González-Avalos, D Samaniego-Castruita, A Das, ... Proceedings of the National Academy of Sciences 116 (25), 12410-12415, 2019 | 606 | 2019 |
Th2 cells in health and disease T Nakayama, K Hirahara, A Onodera, Y Endo, H Hosokawa, K Shinoda, ... Annual review of immunology 35 (1), 53-84, 2017 | 394 | 2017 |
The polycomb protein Ezh2 regulates differentiation and plasticity of CD4+ T helper type 1 and type 2 cells DJ Tumes, A Onodera, A Suzuki, K Shinoda, Y Endo, C Iwamura, ... Immunity 39 (5), 819-832, 2013 | 292 | 2013 |
The transcription factor Sox4 is a downstream target of signaling by the cytokine TGF-β and suppresses TH2 differentiation M Kuwahara, M Yamashita, K Shinoda, S Tofukuji, A Onodera, ... Nature immunology 13 (8), 778-786, 2012 | 197 | 2012 |
Amphiregulin-producing pathogenic memory T helper 2 cells instruct eosinophils to secrete osteopontin and facilitate airway fibrosis Y Morimoto, K Hirahara, M Kiuchi, T Wada, T Ichikawa, T Kanno, M Okano, ... Immunity 49 (1), 134-150. e6, 2018 | 186 | 2018 |
Asymmetric action of STAT transcription factors drives transcriptional outputs and cytokine specificity K Hirahara, A Onodera, AV Villarino, M Bonelli, G Sciumè, A Laurence, ... Immunity 42 (5), 877-889, 2015 | 161 | 2015 |
Sox5 and c-Maf cooperatively induce Th17 cell differentiation via RORγt induction as downstream targets of Stat3 S Tanaka, A Suto, T Iwamoto, D Kashiwakuma, S Kagami, K Suzuki, ... Journal of Experimental Medicine 211 (9), 1857-1874, 2014 | 133 | 2014 |
CD103hi Treg cells constrain lung fibrosis induced by CD103lo tissue-resident pathogenic CD4 T cells T Ichikawa, K Hirahara, K Kokubo, M Kiuchi, A Aoki, Y Morimoto, ... Nature Immunology 20 (11), 1469-1480, 2019 | 103 | 2019 |
STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells A Onodera, M Yamashita, Y Endo, M Kuwahara, S Tofukuji, H Hosokawa, ... Journal of Experimental Medicine 207 (11), 2493-2506, 2010 | 101 | 2010 |
Epigenetic regulation of T‐helper cell differentiation, memory, and plasticity in allergic asthma DJ Tumes, M Papadopoulos, Y Endo, A Onodera, K Hirahara, ... Immunological Reviews 278 (1), 8-19, 2017 | 95 | 2017 |
Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity H Hosokawa, T Tanaka, Y Suzuki, C Iwamura, S Ohkubo, K Endoh, ... Proceedings of the National Academy of Sciences 110 (12), 4691-4696, 2013 | 90 | 2013 |
The transcription factor T-bet limits amplification of type I IFN transcriptome and circuitry in T helper 1 cells S Iwata, Y Mikami, HW Sun, SR Brooks, D Jankovic, K Hirahara, ... Immunity 46 (6), 983-991. e4, 2017 | 87 | 2017 |
Genome-wide analysis reveals unique regulation of transcription of Th2-specific genes by GATA3 S Horiuchi, A Onodera, H Hosokawa, Y Watanabe, T Tanaka, S Sugano, ... The Journal of Immunology 186 (11), 6378-6389, 2011 | 76 | 2011 |
Myosin light chains 9 and 12 are functional ligands for CD69 that regulate airway inflammation K Hayashizaki, MY Kimura, K Tokoyoda, H Hosokawa, K Shinoda, ... Science Immunology 1 (3), eaaf9154-eaaf9154, 2016 | 68 | 2016 |
Conventional and pathogenic Th2 cells in inflammation, tissue repair, and fibrosis K Kokubo, A Onodera, M Kiuchi, K Tsuji, K Hirahara, T Nakayama Frontiers in immunology 13, 945063, 2022 | 59 | 2022 |
Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells A Onodera, E González-Avalos, CWJ Lio, RO Georges, A Bellacosa, ... Genome Biology 22 (1), 186, 2021 | 55 | 2021 |
ACC1 determines memory potential of individual CD4+ T cells by regulating de novo fatty acid biosynthesis Y Endo, A Onodera, K Obata-Ninomiya, R Koyama-Nasu, HK Asou, T Ito, ... Nature Metabolism 1 (2), 261-275, 2019 | 53 | 2019 |
DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells T Yamamoto, Y Endo, A Onodera, K Hirahara, HK Asou, T Nakajima, ... Nature communications 9 (1), 4231, 2018 | 46 | 2018 |
Memory type 2 helper T cells induce long-lasting antitumor immunity by activating natural killer cells M Kitajima, T Ito, DJ Tumes, Y Endo, A Onodera, K Hashimoto, ... Cancer research 71 (14), 4790-4798, 2011 | 46 | 2011 |
Histone acetylation mediated by Brd1 is crucial for Cd8 gene activation during early thymocyte development Y Mishima, C Wang, S Miyagi, A Saraya, H Hosokawa, ... Nature communications 5 (1), 5872, 2014 | 38 | 2014 |