A community-driven global reconstruction of human metabolism I Thiele, N Swainston, RMT Fleming, A Hoppe, S Sahoo, MK Aurich, ... Nature biotechnology 31 (5), 419-425, 2013 | 1186 | 2013 |
Escher: a web application for building, sharing, and embedding data-rich visualizations of biological pathways ZA King, A Dräger, A Ebrahim, N Sonnenschein, NE Lewis, BO Palsson PLoS computational biology 11 (8), e1004321, 2015 | 392 | 2015 |
MEMOTE for standardized genome-scale metabolic model testing C Lieven, ME Beber, BG Olivier, FT Bergmann, M Ataman, P Babaei, ... Nature biotechnology 38 (3), 272-276, 2020 | 354 | 2020 |
A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism H Lu, F Li, BJ Sánchez, Z Zhu, G Li, I Domenzain, S Marcišauskas, ... Nature Communications 10 (1), 1-13, 2019 | 298 | 2019 |
Personalized Whole-Cell Kinetic Models of Metabolism for Discovery in Genomics and Pharmacodynamics A Bordbar, D McCloskey, DC Zielinski, N Sonnenschein, N Jamshidi, ... Cell Systems 1 (4), 283-292, 2015 | 116 | 2015 |
Evolution reveals a glutathione-dependent mechanism of 3-hydroxypropionic acid tolerance KR Kildegaard, BM Hallström, TH Blicher, N Sonnenschein, NB Jensen, ... Metabolic engineering 26, 57-66, 2014 | 96 | 2014 |
Reconstruction of a catalogue of genome-scale metabolic models with enzymatic constraints using GECKO 2.0 I Domenzain, B Sánchez, M Anton, EJ Kerkhoven, A Millán-Oropeza, ... Nature Communications 13, 2022 | 82 | 2022 |
Improving reproducibility in synthetic biology MM Jessop-Fabre, N Sonnenschein Frontiers in Bioengineering and Biotechnology 7, 18, 2019 | 82 | 2019 |
Engineering an NADPH/NADP+ Redox Biosensor in Yeast J Zhang, N Sonnenschein, TPB Pihl, KR Pedersen, MK Jensen, ... ACS synthetic biology 5 (12), 1546-1556, 2016 | 80 | 2016 |
Integration of enzymatic data in Bacillus subtilis genome-scale metabolic model improves phenotype predictions and enables in silico design of poly-γ-glutamic acid production … MJ Massaiu, I., Pasotti, L., Sonnenschein, N., Rama, E., Cavaletti, M ... Microbial Cell Factories 18 (3), 2019 | 78 | 2019 |
Cameo: A Python Library for Computer Aided Metabolic Engineering and Optimization of Cell Factories JGR Cardoso, K Jensen, C Lieven, AS Lærke Hansen, S Galkina, ... ACS synthetic biology 7 (4), 1163-1166, 2018 | 69 | 2018 |
Whole-cell modeling in yeast predicts compartment-specific proteome constraints that drive metabolic strategies IE Elsemman, A Rodriguez Prado, P Grigaitis, M Garcia Albornoz, ... Nature Communications 13 (1), 1-12, 2022 | 66 | 2022 |
Do genome‐scale models need exact solvers or clearer standards? A Ebrahim, E Almaas, E Bauer, A Bordbar, AP Burgard, RL Chang, ... Molecular Systems Biology 11 (10), 831, 2015 | 64 | 2015 |
Analog regulation of metabolic demand N Sonnenschein, M Geertz, G Muskhelishvili, MT Hütt BMC systems biology 5 (1), 40, 2011 | 63 | 2011 |
A genome-scale metabolic model for Methylococcus capsulatus (Bath) suggests reduced efficiency electron transfer to the particulate methane monooxygenase C Lieven, LAH Petersen, SB Jørgensen, KV Gernaey, MJ Herrgard, ... Frontiers in microbiology 9, 2947, 2018 | 56 | 2018 |
Systems biology solutions for biochemical production challenges ASL Hansen, RM Lennen, N Sonnenschein, MJ Herrgård Current Opinion in Biotechnology 45, 85-91, 2017 | 53 | 2017 |
Artefacts in statistical analyses of network motifs: general framework and application to metabolic networks ME Beber, C Fretter, S Jain, N Sonnenschein, M Müller-Hannemann, ... Journal of The Royal Society Interface, 2012 | 46 | 2012 |
OptCouple: Joint simulation of gene knockouts, insertions and medium modifications for prediction of growth-coupled strain designs K Jensen, V Broeken, ASL Hansen, N Sonnenschein, MJ Herrgård Metabolic engineering communications 8, e00087, 2019 | 45 | 2019 |
Analysis of genetic variation and potential applications in genome-scale metabolic modeling JGR Cardoso, MR Andersen, MJ Herrgård, N Sonnenschein Frontiers in bioengineering and biotechnology 3, 13, 2015 | 42 | 2015 |
Laboratory evolution reveals general and specific tolerance mechanisms for commodity chemicals RM Lennen, HG Lim, K Jensen, ET Mohammed, PV Phaneuf, MH Noh, ... Metabolic Engineering, 2023 | 36 | 2023 |