Posttranscriptional control of T cell effector function by aerobic glycolysis CH Chang, JD Curtis, LB Maggi, B Faubert, AV Villarino, D O’Sullivan, ... Cell 153 (6), 1239-1251, 2013 | 2131 | 2013 |
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint RG Jones, DR Plas, S Kubek, M Buzzai, J Mu, Y Xu, MJ Birnbaum, ... Molecular cell 18 (3), 283-293, 2005 | 1927 | 2005 |
Enhancing CD8 T-cell memory by modulating fatty acid metabolism EL Pearce, MC Walsh, PJ Cejas, GM Harms, H Shen, LS Wang, ... Nature 460 (7251), 103-107, 2009 | 1694 | 2009 |
Tumor suppressors and cell metabolism: a recipe for cancer growth RG Jones, CB Thompson Genes & development 23 (5), 537-548, 2009 | 1383 | 2009 |
Fueling immunity: insights into metabolism and lymphocyte function EL Pearce, MC Poffenberger, CH Chang, RG Jones Science 342 (6155), 1242454, 2013 | 1371 | 2013 |
Function of PI3Kγ in thymocyte development, T cell activation, and neutrophil migration T Sasaki, J Irie-Sasaki, RG Jones, AJ Oliveira-dos-Santos, WL Stanford, ... Science 287 (5455), 1040-1046, 2000 | 1329 | 2000 |
Toll-like receptor–induced changes in glycolytic metabolism regulate dendritic cell activation CM Krawczyk, T Holowka, J Sun, J Blagih, E Amiel, RJ DeBerardinis, ... Blood, The Journal of the American Society of Hematology 115 (23), 4742-4749, 2010 | 1253 | 2010 |
Itaconate links inhibition of succinate dehydrogenase with macrophage metabolic remodeling and regulation of inflammation V Lampropoulou, A Sergushichev, M Bambouskova, S Nair, EE Vincent, ... Cell metabolism 24 (1), 158-166, 2016 | 1180 | 2016 |
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth M Buzzai, RG Jones, RK Amaravadi, JJ Lum, RJ DeBerardinis, F Zhao, ... Cancer research 67 (14), 6745-6752, 2007 | 1121 | 2007 |
TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation B Everts, E Amiel, SCC Huang, AM Smith, CH Chang, WY Lam, ... Nature immunology 15 (4), 323-332, 2014 | 1061 | 2014 |
AMPK is a negative regulator of the Warburg effect and suppresses tumor growth in vivo B Faubert, G Boily, S Izreig, T Griss, B Samborska, Z Dong, F Dupuy, ... Cell metabolism 17 (1), 113-124, 2013 | 982 | 2013 |
Hypoxia-induced energy stress regulates mRNA translation and cell growth L Liu, TP Cash, RG Jones, B Keith, CB Thompson, MC Simon Molecular cell 21 (4), 521-531, 2006 | 756 | 2006 |
Selection of the T cell repertoire E Sebzda, S Mariathasan, T Ohteki, R Jones, MF Bachmann, PS Ohashi Annual review of immunology 17 (1), 829-874, 1999 | 709 | 1999 |
The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo J Blagih, F Coulombe, EE Vincent, F Dupuy, G Galicia-Vázquez, ... Immunity 42 (1), 41-54, 2015 | 633 | 2015 |
A roadmap for interpreting 13C metabolite labeling patterns from cells JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ... Current opinion in biotechnology 34, 189-201, 2015 | 619 | 2015 |
Serine is an essential metabolite for effector T cell expansion EH Ma, G Bantug, T Griss, S Condotta, RM Johnson, B Samborska, ... Cell metabolism 25 (2), 345-357, 2017 | 574 | 2017 |
CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability GJW Van Der Windt, D O’Sullivan, B Everts, SCC Huang, MD Buck, ... Proceedings of the National Academy of Sciences 110 (35), 14336-14341, 2013 | 543 | 2013 |
PDK1-dependent metabolic reprogramming dictates metastatic potential in breast cancer F Dupuy, S Tabariès, S Andrzejewski, Z Dong, J Blagih, MG Annis, ... Cell metabolism 22 (4), 577-589, 2015 | 534 | 2015 |
Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress K Zaugg, Y Yao, PT Reilly, K Kannan, R Kiarash, J Mason, P Huang, ... Genes & development 25 (10), 1041-1051, 2011 | 521 | 2011 |
AMPK maintains cellular metabolic homeostasis through regulation of mitochondrial reactive oxygen species RC Rabinovitch, B Samborska, B Faubert, EH Ma, SP Gravel, ... Cell reports 21 (1), 1-9, 2017 | 474 | 2017 |