| Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry SP Rohrer, ET Birzin, RT Mosley, SC Berk, SM Hutchins, DM Shen, ... Science 282 (5389), 737-740, 1998 | 573 | 1998 |
| Novel peroxisome proliferator-activated receptor (PPAR) γ and PPARδ ligands produce distinct biological effects J Berger, MD Leibowitz, TW Doebber, A Elbrecht, B Zhang, G Zhou, ... Journal of Biological Chemistry 274 (10), 6718-6725, 1999 | 557 | 1999 |
| Distinct properties and advantages of a novel peroxisome proliferator-activated protein γ selective modulator JP Berger, AE Petro, KL Macnaul, LJ Kelly, BB Zhang, K Richards, ... Molecular Endocrinology 17 (4), 662-676, 2003 | 402 | 2003 |
| Nucleoside, nucleotide, and non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA-polymerase MJ Sofia, W Chang, PA Furman, RT Mosley, BS Ross Journal of medicinal chemistry 55 (6), 2481-2531, 2012 | 352 | 2012 |
| Chemical similarity using physiochemical property descriptors SK Kearsley, S Sallamack, EM Fluder, JD Andose, RT Mosley, ... Journal of Chemical Information and Computer Sciences 36 (1), 118-127, 1996 | 350 | 1996 |
| What's all the FLAP about?: 5-lipoxygenase-activating protein inhibitors for inflammatory diseases JF Evans, AD Ferguson, RT Mosley, JH Hutchinson Trends in pharmacological sciences 29 (2), 72-78, 2008 | 297 | 2008 |
| Design and Pharmacology of N-[(3 R)-1, 2, 3, 4-Tetrahydroisoquinolinium-3-ylcarbonyl]-(1 R)-1-(4-chlorobenzyl)-2-[4-cyclohexyl-4-(1 H-1, 2, 4-triazol-1-ylmethyl) piperidin-1-yl … IK Sebhat, WJ Martin, Z Ye, K Barakat, RT Mosley, DBR Johnston, ... Journal of medicinal chemistry 45 (21), 4589-4593, 2002 | 225 | 2002 |
| Molecular determinants of ligand binding to the human melanocortin-4 receptor Y Yang, TM Fong, CJ Dickinson, C Mao, JY Li, MR Tota, R Mosley, ... Biochemistry 39 (48), 14900-14911, 2000 | 224 | 2000 |
| Selective small-molecule agonists of G protein–coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice CP Tan, Y Feng, YP Zhou, GJ Eiermann, A Petrov, C Zhou, S Lin, ... Diabetes 57 (8), 2211-2219, 2008 | 211 | 2008 |
| Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor subtype 2 L Yang, SC Berk, SP Rohrer, RT Mosley, L Guo, DJ Underwood, ... Proceedings of the National Academy of Sciences 95 (18), 10836-10841, 1998 | 176 | 1998 |
| 6H-Benzo [c] chromen-6-one derivatives as selective ERβ agonists W Sun, LD Cama, ET Birzin, S Warrier, L Locco, R Mosley, ML Hammond, ... Bioorganic & medicinal chemistry letters 16 (6), 1468-1472, 2006 | 173 | 2006 |
| Structure and chemistry of apicidins, a class of novel cyclic tetrapeptides without a terminal α-keto epoxide as inhibitors of histone deacetylase with potent antiprotozoal … SB Singh, DL Zink, JM Liesch, RT Mosley, AW Dombrowski, GF Bills, ... The Journal of Organic Chemistry 67 (3), 815-825, 2002 | 172 | 2002 |
| Isolation and structure of chaetomellic acids A and B from Chaetomella acutiseta: farnesyl pyrophosphate mimic inhibitors of Ras farnesyl-protein transferase SB Singh, DL Zink, JM Liesch, MA Goetz, RG Jenkins, M Nallin-Omstead, ... Tetrahedron 49 (27), 5917-5926, 1993 | 146 | 1993 |
| Molecular interaction of Agouti protein and Agouti-related protein with human melanocortin receptors MR Tota, TS Smith, C Mao, T MacNeil, RT Mosley, LHT Van der Ploeg, ... Biochemistry 38 (3), 897-904, 1999 | 142 | 1999 |
| Structure of hepatitis C virus polymerase in complex with primer-template RNA RT Mosley, TE Edwards, E Murakami, AM Lam, RL Grice, J Du, MJ Sofia, ... Journal of virology 86 (12), 6503-6511, 2012 | 141 | 2012 |
| Attenuating pregnane X receptor (PXR) activation: a molecular modelling approach YD Gao, SH Olson, JM Balkovec, Y Zhu, I Royo, J Yabut, R Evers, EY Tan, ... Xenobiotica 37 (2), 124-138, 2007 | 115 | 2007 |
| Estrogen receptor ligands. II. Discovery of benzoxathiins as potent, selective estrogen receptor α modulators S Kim, JY Wu, ET Birzin, K Frisch, W Chan, LY Pai, YT Yang, RT Mosley, ... Journal of medicinal chemistry 47 (9), 2171-2175, 2004 | 108 | 2004 |
| Discovery of 5-aryloxy-2, 4-thiazolidinediones as potent GPR40 agonists C Zhou, C Tang, E Chang, M Ge, S Lin, E Cline, CP Tan, Y Feng, YP Zhou, ... Bioorganic & Medicinal Chemistry Letters 20 (3), 1298-1301, 2010 | 98 | 2010 |
| The differential interactions of peroxisome proliferator-activated receptor γ ligands with Tyr473 is a physical basis for their unique biological activities M Einstein, TE Akiyama, GA Castriota, CF Wang, B McKeever, RT Mosley, ... Molecular Pharmacology 73 (1), 62-74, 2008 | 94 | 2008 |
| Selective PPARγ modulators with improved pharmacological profiles K Liu, RM Black, JJ Acton III, R Mosley, S Debenham, R Abola, M Yang, ... Bioorganic & medicinal chemistry letters 15 (10), 2437-2440, 2005 | 81 | 2005 |
