Epithelial—mesenchymal and mesenchymal—epithelial transitions in carcinoma progression H Hugo, ML Ackland, T Blick, MG Lawrence, JA Clements, ED Williams, ... Journal of cellular physiology 213 (2), 374-383, 2007 | 1412 | 2007 |
Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling R Pidsley, E Zotenko, TJ Peters, MG Lawrence, GP Risbridger, P Molloy, ... Genome biology 17 (1), 208, 2016 | 1229 | 2016 |
Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus MG Lawrence, J Lai, JA Clements Endocrine reviews 31 (4), 407-446, 2010 | 310 | 2010 |
Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories RA Taylor, M Fraser, J Livingstone, SMG Espiritu, H Thorne, V Huang, ... Nature communications 8 (1), 1-10, 2017 | 236 | 2017 |
Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer … TL Veveris-Lowe, MG Lawrence, RL Collard, L Bui, AC Herington, ... Endocrine-related cancer 12 (3), 631-643, 2005 | 194 | 2005 |
Patient-derived Xenografts Reveal that Intraductal Carcinoma of the Prostate Is a Prominent Pathology in BRCA2 Mutation Carriers with Prostate Cancer and … GP Risbridger, RA Taylor, D Clouston, A Sliwinski, H Thorne, S Hunter, ... European urology 67 (3), 496-503, 2015 | 153 | 2015 |
Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells MG Lawrence, NV Margaryan, D Loessner, A Collins, KM Kerr, M Turner, ... The Prostate 71 (11), 1198-1209, 2011 | 126 | 2011 |
A preclinical xenograft model of prostate cancer using human tumors MG Lawrence, RA Taylor, R Toivanen, J Pedersen, S Norden, DW Pook, ... Nature protocols 8 (5), 836, 2013 | 121 | 2013 |
Patient-derived models of abiraterone-and enzalutamide-resistant prostate cancer reveal sensitivity to ribosome-directed therapy MG Lawrence, D Obinata, S Sandhu, LA Selth, SQ Wong, LH Porter, ... European urology 74 (5), 562-572, 2018 | 106 | 2018 |
Systematic review links the prevalence of intraductal carcinoma of the prostate to prostate cancer risk categories LH Porter, MG Lawrence, D Ilic, D Clouston, DM Bolton, M Frydenberg, ... European urology 72 (4), 492-495, 2017 | 103 | 2017 |
Enduring epigenetic landmarks define the cancer microenvironment R Pidsley, MG Lawrence, E Zotenko, B Niranjan, A Statham, J Song, ... Genome research 28 (5), 625-638, 2018 | 93 | 2018 |
A community-based model of rapid autopsy in end-stage cancer patients. K Alsop, H Thorne, S Sandhu, A Hamilton, C Mintoff, E Christie, O Spruyt, ... Nature biotechnology 34 (10), 1010, 2016 | 88 | 2016 |
Proteomic profiling of human prostate cancer-associated fibroblasts (CAF) reveals LOXL2-dependent regulation of the tumor microenvironment EV Nguyen, BA Pereira, MG Lawrence, X Ma, RJ Rebello, H Chan, ... Molecular & Cellular Proteomics 18 (7), 1410-1427, 2019 | 85 | 2019 |
A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer AK Clark, AV Taubenberger, RA Taylor, B Niranjan, ZY Chea, E Zotenko, ... Biomaterials 34 (20), 4777-4785, 2013 | 77 | 2013 |
Cancer Plasticity: The Role of mRNA Translation LJ Lee, D Papadopoli, M Jewer, S Del Rincon, I Topisirovic, ... Trends in Cancer, 2020 | 71 | 2020 |
Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity I Takizawa, MG Lawrence, P Balanathan, R Rebello, HB Pearson, E Garg, ... Oncotarget 6 (2), 604, 2015 | 60 | 2015 |
Breast cancer polygenic risk score and contralateral breast cancer risk I Kramer, MJ Hooning, N Mavaddat, M Hauptmann, R Keeman, ... The American Journal of Human Genetics 107 (5), 837-848, 2020 | 57 | 2020 |
Intraductal carcinoma of the prostate can evade androgen deprivation, with emergence of castrate‐tolerant cells LH Porter, K Hashimoto, MG Lawrence, C Pezaro, D Clouston, H Wang, ... BJU international 121 (6), 971-978, 2018 | 53 | 2018 |
The role of kallikrein-related peptidases in prostate cancer: potential involvement in an epithelial to mesenchymal transition AK Whitbread, TL Veveris-Lowe, MG Lawrence, DL Nicol, JA Clements Biological chemistry 387 (6), 707-714, 2006 | 53 | 2006 |
The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology GP Risbridger, AK Clark, LH Porter, R Toivanen, A Bakshi, NL Lister, ... Nature Communications 12 (1), 1-17, 2021 | 48 | 2021 |