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Mitchell Lawrence
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Epithelial—mesenchymal and mesenchymal—epithelial transitions in carcinoma progression
H Hugo, ML Ackland, T Blick, MG Lawrence, JA Clements, ED Williams, ...
Journal of cellular physiology 213 (2), 374-383, 2007
14122007
Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling
R Pidsley, E Zotenko, TJ Peters, MG Lawrence, GP Risbridger, P Molloy, ...
Genome biology 17 (1), 208, 2016
12292016
Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus
MG Lawrence, J Lai, JA Clements
Endocrine reviews 31 (4), 407-446, 2010
3102010
Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories
RA Taylor, M Fraser, J Livingstone, SMG Espiritu, H Thorne, V Huang, ...
Nature communications 8 (1), 1-10, 2017
2362017
Kallikrein 4 (hK4) and prostate-specific antigen (PSA) are associated with the loss of E-cadherin and an epithelial-mesenchymal transition (EMT)-like effect in prostate cancer …
TL Veveris-Lowe, MG Lawrence, RL Collard, L Bui, AC Herington, ...
Endocrine-related cancer 12 (3), 631-643, 2005
1942005
Patient-derived Xenografts Reveal that Intraductal Carcinoma of the Prostate Is a Prominent Pathology in BRCA2 Mutation Carriers with Prostate Cancer and …
GP Risbridger, RA Taylor, D Clouston, A Sliwinski, H Thorne, S Hunter, ...
European urology 67 (3), 496-503, 2015
1532015
Reactivation of embryonic nodal signaling is associated with tumor progression and promotes the growth of prostate cancer cells
MG Lawrence, NV Margaryan, D Loessner, A Collins, KM Kerr, M Turner, ...
The Prostate 71 (11), 1198-1209, 2011
1262011
A preclinical xenograft model of prostate cancer using human tumors
MG Lawrence, RA Taylor, R Toivanen, J Pedersen, S Norden, DW Pook, ...
Nature protocols 8 (5), 836, 2013
1212013
Patient-derived models of abiraterone-and enzalutamide-resistant prostate cancer reveal sensitivity to ribosome-directed therapy
MG Lawrence, D Obinata, S Sandhu, LA Selth, SQ Wong, LH Porter, ...
European urology 74 (5), 562-572, 2018
1062018
Systematic review links the prevalence of intraductal carcinoma of the prostate to prostate cancer risk categories
LH Porter, MG Lawrence, D Ilic, D Clouston, DM Bolton, M Frydenberg, ...
European urology 72 (4), 492-495, 2017
1032017
Enduring epigenetic landmarks define the cancer microenvironment
R Pidsley, MG Lawrence, E Zotenko, B Niranjan, A Statham, J Song, ...
Genome research 28 (5), 625-638, 2018
932018
A community-based model of rapid autopsy in end-stage cancer patients.
K Alsop, H Thorne, S Sandhu, A Hamilton, C Mintoff, E Christie, O Spruyt, ...
Nature biotechnology 34 (10), 1010, 2016
882016
Proteomic profiling of human prostate cancer-associated fibroblasts (CAF) reveals LOXL2-dependent regulation of the tumor microenvironment
EV Nguyen, BA Pereira, MG Lawrence, X Ma, RJ Rebello, H Chan, ...
Molecular & Cellular Proteomics 18 (7), 1410-1427, 2019
852019
A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer-associated fibroblasts in human prostate cancer
AK Clark, AV Taubenberger, RA Taylor, B Niranjan, ZY Chea, E Zotenko, ...
Biomaterials 34 (20), 4777-4785, 2013
772013
Cancer Plasticity: The Role of mRNA Translation
LJ Lee, D Papadopoli, M Jewer, S Del Rincon, I Topisirovic, ...
Trends in Cancer, 2020
712020
Estrogen receptor alpha drives proliferation in PTEN-deficient prostate carcinoma by stimulating survival signaling, MYC expression and altering glucose sensitivity
I Takizawa, MG Lawrence, P Balanathan, R Rebello, HB Pearson, E Garg, ...
Oncotarget 6 (2), 604, 2015
602015
Breast cancer polygenic risk score and contralateral breast cancer risk
I Kramer, MJ Hooning, N Mavaddat, M Hauptmann, R Keeman, ...
The American Journal of Human Genetics 107 (5), 837-848, 2020
572020
Intraductal carcinoma of the prostate can evade androgen deprivation, with emergence of castrate‐tolerant cells
LH Porter, K Hashimoto, MG Lawrence, C Pezaro, D Clouston, H Wang, ...
BJU international 121 (6), 971-978, 2018
532018
The role of kallikrein-related peptidases in prostate cancer: potential involvement in an epithelial to mesenchymal transition
AK Whitbread, TL Veveris-Lowe, MG Lawrence, DL Nicol, JA Clements
Biological chemistry 387 (6), 707-714, 2006
532006
The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology
GP Risbridger, AK Clark, LH Porter, R Toivanen, A Bakshi, NL Lister, ...
Nature Communications 12 (1), 1-17, 2021
482021
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