| Chemical space of DNA-encoded libraries: Miniperspective RM Franzini, C Randolph Journal of medicinal chemistry 59 (14), 6629-6644, 2016 | 247 | 2016 |
| DNA-encoded chemical libraries: advancing beyond conventional small-molecule libraries RM Franzini, D Neri, J Scheuermann Accounts of chemical research 47 (4), 1247-1255, 2014 | 240 | 2014 |
| Dual-display of small molecules enables the discovery of ligand pairs and facilitates affinity maturation M Wichert, N Krall, W Decurtins, RM Franzini, F Pretto, P Schneider, ... Nature chemistry 7 (3), 241-249, 2015 | 206 | 2015 |
| Efficient nucleic acid detection by templated reductive quencher release RM Franzini, ET Kool Journal of the American Chemical Society 131 (44), 16021-16023, 2009 | 166 | 2009 |
| Automated screening for small organic ligands using DNA-encoded chemical libraries W Decurtins, M Wichert, RM Franzini, F Buller, MA Stravs, Y Zhang, D Neri, ... Nature protocols 11 (4), 764-780, 2016 | 128 | 2016 |
| Bioorthogonal removal of 3-isocyanopropyl groups enables the controlled release of fluorophores and drugs in vivo J Tu, M Xu, S Parvez, RT Peterson, RM Franzini Journal of the American Chemical Society 140 (27), 8410-8414, 2018 | 117 | 2018 |
| Identification of Structure–Activity Relationships from Screening a Structurally Compact DNA‐Encoded Chemical Library RM Franzini, T Ekblad, N Zhong, M Wichert, W Decurtins, A Nauer, ... Angewandte Chemie 127 (13), 3999-4003, 2015 | 105 | 2015 |
| Achievements, Challenges, and Opportunities in DNA‐Encoded Library Research: An Academic Point of View LH Yuen, RM Franzini ChemBioChem 18 (9), 829-836, 2017 | 92 | 2017 |
| A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+-Dependent Enzymes LH Yuen, S Dana, Y Liu, SI Bloom, AG Thorsell, D Neri, AJ Donato, ... Journal of the American Chemical Society 141 (13), 5169-5181, 2019 | 89 | 2019 |
| Mechanisms and substituent effects of metal-free bioorthogonal reactions T Deb, J Tu, RM Franzini Chemical reviews 121 (12), 6850-6914, 2021 | 87 | 2021 |
| 7‐Azidomethoxy‐coumarins as profluorophores for templated nucleic acid detection RM Franzini, ET Kool ChemBioChem 9 (18), 2981-2988, 2008 | 87 | 2008 |
| Stable, reactive, and orthogonal tetrazines: dispersion forces promote the cycloaddition with isonitriles J Tu, D Svatunek, S Parvez, AC Liu, BJ Levandowski, HJ Eckvahl, ... Angewandte Chemie International Edition 58 (27), 9043-9048, 2019 | 84 | 2019 |
| Metal binding to bipyridine-modified PNA RM Franzini, RM Watson, GK Patra, RM Breece, DL Tierney, MP Hendrich, ... Inorganic chemistry 45 (24), 9798-9811, 2006 | 83 | 2006 |
| Dissociative bioorthogonal reactions J Tu, M Xu, RM Franzini ChemBioChem 20 (13), 1615-1627, 2019 | 74 | 2019 |
| Pattern‐based detection of toxic metals in surface water with DNA polyfluorophores LH Yuen, RM Franzini, S Wang, P Crisalli, V Singh, W Jiang, ET Kool Angewandte Chemie International Edition 53 (21), 5361-5365, 2014 | 74 | 2014 |
| Systematic evaluation and optimization of modification reactions of oligonucleotides with amines and carboxylic acids for the synthesis of DNA-encoded chemical libraries RM Franzini, F Samain, M Abd Elrahman, G Mikutis, A Nauer, ... Bioconjugate chemistry 25 (8), 1453-1461, 2014 | 71 | 2014 |
| Tankyrase 1 inhibitors with drug-like properties identified by screening a DNA-encoded chemical library F Samain, T Ekblad, G Mikutis, N Zhong, M Zimmermann, A Nauer, ... Journal of medicinal chemistry 58 (12), 5143-5149, 2015 | 67 | 2015 |
| Rapid and efficient tetrazine-induced drug release from highly stable benzonorbornadiene derivatives M Xu, J Tu, RM Franzini Chemical Communications 53 (46), 6271-6274, 2017 | 64 | 2017 |
| Large-scale detection of metals with a small set of fluorescent DNA-like chemosensors LH Yuen, RM Franzini, SS Tan, ET Kool Journal of the American Chemical Society 136 (41), 14576-14582, 2014 | 59 | 2014 |
| Isonitrile-responsive and bioorthogonally removable tetrazine protecting groups J Tu, D Svatunek, S Parvez, HJ Eckvahl, M Xu, RT Peterson, KN Houk, ... Chemical science 11 (1), 169-179, 2020 | 50 | 2020 |
