| FGFR3 and Ras gene mutations are mutually exclusive genetic events in urothelial cell carcinoma AH Jebar, CD Hurst, DC Tomlinson, C Johnston, CF Taylor, MA Knowles Oncogene 24 (33), 5218-5225, 2005 | 430 | 2005 |
| FGFR3 protein expression and its relationship to mutation status and prognostic variables in bladder cancer DC Tomlinson, O Baldo, P Harnden, MA Knowles The Journal of pathology 213 (1), 91-98, 2007 | 391 | 2007 |
| An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes G Wheway, M Schmidts, DA Mans, K Szymanska, TMT Nguyen, H Racher, ... Nature cell biology 17 (8), 1074-1087, 2015 | 252 | 2015 |
| Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications C Tiede, AAS Tang, SE Deacon, U Mandal, JE Nettleship, RL Owen, ... Protein Engineering, Design & Selection 27 (5), 145-155, 2014 | 214 | 2014 |
| Affimer proteins are versatile and renewable affinity reagents C Tiede, R Bedford, SJ Heseltine, G Smith, I Wijetunga, R Ross, ... Elife 6, e24903, 2017 | 204 | 2017 |
| Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo FR Lamont, DC Tomlinson, PA Cooper, SD Shnyder, JD Chester, ... British journal of cancer 104 (1), 75-82, 2011 | 202 | 2011 |
| Multidrug-resistant breast cancer: current perspectives HL Martin, L Smith, DC Tomlinson Breast Cancer: targets and therapy, 1-13, 2014 | 182 | 2014 |
| Sonic hedgehog regulates prostatic growth and epithelial differentiation SH Freestone, P Marker, OC Grace, DC Tomlinson, GR Cunha, ... Developmental biology 264 (2), 352-362, 2003 | 179 | 2003 |
| Knockdown by shRNA identifies S249C mutant FGFR3 as a potential therapeutic target in bladder cancer DC Tomlinson, CD Hurst, MA Knowles Oncogene 26 (40), 5889-5899, 2007 | 159 | 2007 |
| Label-free electrochemical impedance biosensor to detect human interleukin-8 in serum with sub-pg/ml sensitivity R Sharma, SE Deacon, D Nowak, SE George, MP Szymonik, AAS Tang, ... Biosensors and Bioelectronics 80, 607-613, 2016 | 145 | 2016 |
| A decade of FGF receptor research in bladder cancer: past, present, and future challenges E di Martino, DC Tomlinson, MA Knowles Advances in urology 2012 (1), 429213, 2012 | 145 | 2012 |
| Fibroblast growth factor receptor 1 promotes proliferation and survival via activation of the mitogen-activated protein kinase pathway in bladder cancer DC Tomlinson, FR Lamont, SD Shnyder, MA Knowles Cancer research 69 (11), 4613-4620, 2009 | 145 | 2009 |
| Hypofibrinolysis in diabetes: a therapeutic target for the reduction of cardiovascular risk K Kearney, D Tomlinson, K Smith, R Ajjan Cardiovascular diabetology 16, 1-17, 2017 | 139 | 2017 |
| Mutant fibroblast growth factor receptor 3 induces intracellular signaling and cellular transformation in a cell type-and mutation-specific manner E Di Martino, CG L'hôte, W Kennedy, DC Tomlinson, MA Knowles Oncogene 28 (48), 4306-4316, 2009 | 131 | 2009 |
| Inactivation of the Rb pathway and overexpression of both isoforms of E2F3 are obligate events in bladder tumours with 6p22 amplification CD Hurst, DC Tomlinson, SV Williams, FM Platt, MA Knowles Oncogene 27 (19), 2716-2727, 2008 | 122 | 2008 |
| Selective and potent proteomimetic inhibitors of intracellular protein–protein interactions A Barnard, K Long, HL Martin, JA Miles, TA Edwards, DC Tomlinson, ... Angewandte Chemie 127 (10), 3003-3008, 2015 | 111 | 2015 |
| FGFR1-induced epithelial to mesenchymal transition through MAPK/PLCγ/COX-2-mediated mechanisms DC Tomlinson, EW Baxter, PM Loadman, MA Hull, MA Knowles PloS one 7 (6), e38972, 2012 | 106 | 2012 |
| Mechanisms of FGFR3 actions in endocrine resistant breast cancer DC Tomlinson, MA Knowles, V Speirs International journal of cancer 130 (12), 2857-2866, 2012 | 105 | 2012 |
| Alternative splicing of fibroblast growth factor receptor 3 produces a secreted isoform that inhibits fibroblast growth factor–induced proliferation and is repressed in … DC Tomlinson, CG L'Hôte, W Kennedy, E Pitt, MA Knowles Cancer research 65 (22), 10441-10449, 2005 | 95 | 2005 |
| High-content, high-throughput screening for the identification of cytotoxic compounds based on cell morphology and cell proliferation markers HL Martin, M Adams, J Higgins, J Bond, EE Morrison, SM Bell, S Warriner, ... PloS one 9 (2), e88338, 2014 | 78 | 2014 |
