| Humanization of antibodies JC Almagro, J Fransson Front Biosci 13 (1), 1619-33, 2008 | 649 | 2008 |
| Use of human germline genes in a CDR homology-based approach to antibody humanization WYK Hwang, JC Almagro, TN Buss, P Tan, J Foote Methods 36 (1), 35-42, 2005 | 210 | 2005 |
| Discrimination between native and intentionally misfolded conformations of proteins: ES/IS, a new method for calculating conformational free energy that uses both dynamics … YN Vorobjev, JC Almagro, J Hermans Proteins: Structure, Function, and Bioinformatics 32 (4), 399-413, 1998 | 194 | 1998 |
| Progress and challenges in the design and clinical development of antibodies for cancer therapy JC Almagro, TR Daniels-Wells, SM Perez-Tapia, ML Penichet Frontiers in immunology 8, 1751, 2018 | 182 | 2018 |
| Identification of differences in the specificity‐determining residues of antibodies that recognize antigens of different size: implications for the rational design of antibody … JC Almagro Journal of Molecular Recognition 17 (2), 132-143, 2004 | 180 | 2004 |
| Canonical structure repertoire of the antigen-binding site of immunoglobulins suggests strong geometrical restrictions associated to the mechanism of immune recognition E Vargas-Madrazo, F Lara-Ochoa, JC Almagro Journal of molecular biology 254 (3), 497-504, 1995 | 157 | 1995 |
| Second antibody modeling assessment (AMA‐II) JC Almagro, A Teplyakov, J Luo, RW Sweet, S Kodangattil, ... Proteins: Structure, Function, and Bioinformatics 82 (8), 1553-1562, 2014 | 139 | 2014 |
| Antibody modeling assessment JC Almagro, MP Beavers, F Hernandez‐Guzman, J Maier, J Shaulsky, ... Proteins: Structure, Function, and Bioinformatics 79 (11), 3050-3066, 2011 | 137 | 2011 |
| Specific epitopes of domains II and III of Bacillus thuringiensis Cry1Ab toxin involved in the sequential interaction with cadherin and aminopeptidase-N receptors in Manduca sexta I Gomez, I Arenas, I Benitez, J Miranda-Rios, B Becerril, R Grande, ... Journal of Biological Chemistry 281 (45), 34032-34039, 2006 | 136 | 2006 |
| Phage display libraries for antibody therapeutic discovery and development JC Almagro, M Pedraza-Escalona, HI Arrieta, SM Pérez-Tapia Antibodies 8 (3), 44, 2019 | 133 | 2019 |
| Antigen‐binding site anatomy and somatic mutations in antibodies that recognize different types of antigens G Raghunathan, J Smart, J Williams, JC Almagro Journal of Molecular Recognition 25 (3), 103-113, 2012 | 95 | 2012 |
| Antibody modeling assessment II. Structures and models A Teplyakov, J Luo, G Obmolova, TJ Malia, R Sweet, RL Stanfield, ... Proteins: Structure, Function, and Bioinformatics 82 (8), 1563-1582, 2014 | 91 | 2014 |
| Natural and man-made V-gene repertoires for antibody discovery WJJ Finlay, JC Almagro Frontiers in immunology 3, 342, 2012 | 90 | 2012 |
| De novo selection of high-affinity antibodies from synthetic fab libraries displayed on phage as pIX fusion proteins L Shi, JC Wheeler, RW Sweet, J Lu, J Luo, M Tornetta, B Whitaker, ... Journal of molecular biology 397 (2), 385-396, 2010 | 83 | 2010 |
| Synthetic antibody libraries focused towards peptide ligands CW Cobaugh, JC Almagro, M Pogson, B Iverson, G Georgiou Journal of molecular biology 378 (3), 622-633, 2008 | 78 | 2008 |
| Phage displayed biomolecules as preventive and therapeutic agents K Manoutcharian, G Gevorkian, A Cano, JC Almagro Current pharmaceutical biotechnology 2 (3), 217-223, 2001 | 68 | 2001 |
| Structural diversity in a human antibody germline library A Teplyakov, G Obmolova, TJ Malia, J Luo, S Muzammil, R Sweet, ... MAbs 8 (6), 1045-1063, 2016 | 58 | 2016 |
| Phage antibody fragments library combining a single human light chain variable region with immune mouse heavy chain variable regions G Rojas, JC Almagro, B Acevedo, JV Gavilondo Journal of Biotechnology 94 (3), 287-298, 2002 | 57 | 2002 |
| Structural differences between the repertoires of mouse and human germline genes and their evolutionary implications JC Almagro, I Hernández, MC Ramírez, E Vargas-Madrazo Immunogenetics 47, 355-363, 1998 | 55 | 1998 |
| Methods of Humanizing and Affinity-Maturing Antibodies JC Almagro, R Reddy, J Fransson US Patent App. 12/578,803, 2010 | 51 | 2010 |
