T cell receptor (TCR) signaling in health and disease K Shah, A Al-Haidari, J Sun, JU Kazi Signal transduction and targeted therapy 6 (1), 412, 2021 | 262 | 2021 |
Oncogenic signaling from the hematopoietic growth factor receptors c-Kit and Flt3 K Masson, L Rönnstrand Cellular signalling 21 (12), 1717-1726, 2009 | 204* | 2009 |
Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML O Lindblad, E Cordero, A Puissant, L Macaulay, A Ramos, NN Kabir, ... Oncogene 35 (39), 5119-5131, 2016 | 121 | 2016 |
Stem cell factor induces HIF-1α at normoxia in hematopoietic cells M Pedersen, T Löfstedt, J Sun, L Holmquist-Mengelbier, S Påhlman, ... Biochemical and biophysical research communications 377 (1), 98-103, 2008 | 97 | 2008 |
Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein … E Heiss, K Masson, C Sundberg, M Pedersen, J Sun, S Bengtsson, ... Blood 108 (5), 1542-1550, 2006 | 95 | 2006 |
The D816V mutation of c-Kit circumvents a requirement for Src family kinases in c-Kit signal transduction J Sun, M Pedersen, L Ronnstrand Journal of Biological Chemistry 284 (17), 11039-11047, 2009 | 90 | 2009 |
Suppressor of cytokine signaling 6 (SOCS6) negatively regulates Flt3 signal transduction through direct binding to phosphorylated tyrosines 591 and 919 of Flt3 JU Kazi, J Sun, B Phung, F Zadjali, A Flores-Morales, L Rönnstrand Journal of Biological Chemistry 287 (43), 36509-36517, 2012 | 75 | 2012 |
Structural basis for c-KIT inhibition by the suppressor of cytokine signaling 6 (SOCS6) ubiquitin ligase F Zadjali, ACW Pike, M Vesterlund, J Sun, C Wu, SSC Li, L Rönnstrand, ... Journal of Biological Chemistry 286 (1), 480-490, 2011 | 68 | 2011 |
C-KIT signaling depends on microphthalmia-associated transcription factor for effects on cell proliferation B Phung, J Sun, A Schepsky, E Steingrimsson, L Rönnstrand PloS one 6 (8), e24064, 2011 | 66 | 2011 |
Gab2 is involved in differential phosphoinositide 3-kinase signaling by two splice forms of c-Kit J Sun, M Pedersen, L Ronnstrand Journal of Biological Chemistry 283 (41), 27444-27451, 2008 | 66 | 2008 |
Grb2 mediates negative regulation of stem cell factor receptor/c-Kit signaling by recruitment of Cbl J Sun, M Pedersen, S Bengtsson, L Rönnstrand Experimental cell research 313 (18), 3935-3942, 2007 | 60 | 2007 |
Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosis H Ke, JU Kazi, H Zhao, J Sun Cell & Bioscience 6, 1-10, 2016 | 51 | 2016 |
The proto-oncogene transcription factor Ets1 regulates neural crest development through histone deacetylase 1 to mediate output of bone morphogenetic protein signaling C Wang, RKT Kam, W Shi, Y Xia, X Chen, Y Cao, J Sun, Y Du, G Lu, ... Journal of Biological Chemistry 290 (36), 21925-21938, 2015 | 46 | 2015 |
The role of HOXB2 and HOXB3 in acute myeloid leukemia O Lindblad, RA Chougule, SA Moharram, NN Kabir, J Sun, JU Kazi, ... Biochemical and biophysical research communications 467 (4), 742-747, 2015 | 44 | 2015 |
SOCS6 is a selective suppressor of receptor tyrosine kinase signaling NN Kabir, J Sun, L Rönnstrand, JU Kazi Tumor Biology 35, 10581-10589, 2014 | 42 | 2014 |
The c-Kit/D816V mutation eliminates the differences in signal transduction and biological responses between two isoforms of c-Kit M Pedersen, L Rönnstrand, J Sun Cellular signalling 21 (3), 413-418, 2009 | 41 | 2009 |
Inhibition of MEK5 by BIX02188 induces apoptosis in cells expressing the oncogenic mutant FLT3-ITD E Razumovskaya, J Sun, L Rönnstrand Biochemical and biophysical research communications 412 (2), 307-312, 2011 | 40 | 2011 |
The NF‐κB‐modulated miR‐19a‐3p enhances malignancy of human ovarian cancer cells through inhibition of IGFBP‐3 expression R Bai, Z Cui, Y Ma, Y Wu, N Wang, L Huang, Q Yao, J Sun Molecular carcinogenesis 58 (12), 2254-2265, 2019 | 38 | 2019 |
Homocysteine accelerates atherosclerosis by inhibiting scavenger receptor class B member1 via DNMT3b/SP1 pathway W Guo, H Zhang, A Yang, P Ma, L Sun, M Deng, C Mao, J Xiong, J Sun, ... Journal of Molecular and Cellular Cardiology 138, 34-48, 2020 | 34 | 2020 |
EPO-Independent Functional EPO Receptor in Breast Cancer Enhances Estrogen Receptor Activity and Promotes Cell Proliferation S Reinbothe, AM Larsson, M Vaapil, C Wiegerup, J Sun, A Jögi, ... Biochemical and Biophysical Research Communications, 2014 | 33 | 2014 |