A conditional knockout resource for the genome-wide study of mouse gene function WC Skarnes, B Rosen, AP West, M Koutsourakis, W Bushell, V Iyer, ... Nature 474 (7351), 337-342, 2011 | 1811 | 2011 |
A new logic for DNA engineering using recombination in Escherichia coli Y Zhang, F Buchholz, JPP Muyrers, AF Stewart Nature genetics 20 (2), 123-128, 1998 | 1621 | 1998 |
High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP CI Rodríguez, F Buchholz, J Galloway, R Sequerra, J Kasper, R Ayala, ... Nature genetics 25 (2), 139-140, 2000 | 1330 | 2000 |
The PHD finger: implications for chromatin-mediated transcriptional regulation R Aasland, TJ Gibson, AF Stewart Trends in biochemical sciences 20 (2), 56-59, 1995 | 1106 | 1995 |
The transcriptional and epigenomic foundations of ground state pluripotency H Marks, T Kalkan, R Menafra, S Denissov, K Jones, H Hofemeister, ... Cell 149 (3), 590-604, 2012 | 956 | 2012 |
Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene HM Jantzen, U Strähle, B Gloss, F Stewart, W Schmid, M Boshart, ... Cell 49 (1), 29-38, 1987 | 832 | 1987 |
High-throughput engineering of the mouse genome coupled with high-resolution expression analysis DM Valenzuela, AJ Murphy, D Frendewey, NW Gale, AN Economides, ... Nature biotechnology 21 (6), 652-659, 2003 | 772 | 2003 |
The knockout mouse project Nature genetics 36 (9), 921-924, 2004 | 763 | 2004 |
Rapid modification of bacterial artificial chromosomes by ET-recombination JPP Muyrers, Y Zhang, G Testa, AF Stewart Nucleic acids research 27 (6), 1555-1557, 1999 | 735 | 1999 |
The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4 A Roguev, D Schaft, A Shevchenko, WWMP Pijnappel, M Wilm, ... The EMBO journal 20 (24), 7137-7148, 2001 | 713 | 2001 |
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals I Poser, M Sarov, JRA Hutchins, JK Hériché, Y Toyoda, A Pozniakovsky, ... Nature methods 5 (5), 409-415, 2008 | 667 | 2008 |
Heterodimerization of the Drosophila ecdysone receptor with retinoid X receptor and ultraspiracle HE Thomas, HG Stunnenberg, AF Stewart Nature 362 (6419), 471-475, 1993 | 593 | 1993 |
DNA cloning by homologous recombination in Escherichia coli Y Zhang, JPP Muyrers, G Testa, AF Stewart Nature biotechnology 18 (12), 1314-1317, 2000 | 590 | 2000 |
Improved properties of FLP recombinase evolved by cycling mutagenesis F Buchholz, PO Angrand, AF Stewart Nature biotechnology 16 (7), 657-662, 1998 | 554 | 1998 |
The SANT domain: a putative DNA-binding domain in the SWI-SNF and ADA complexes, the transcriptional corepressor N-CoR and TFIIIB R Aasland, AF Stewart, T Gibson Trends in biochemical sciences 3 (21), 87-88, 1996 | 490 | 1996 |
Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting J Fu, X Bian, S Hu, H Wang, F Huang, PM Seibert, A Plaza, L Xia, ... Nature biotechnology 30 (5), 440-446, 2012 | 483 | 2012 |
Codon‐improved Cre recombinase (iCre) expression in the mouse DR Shimshek, J Kim, MR Hübner, DJ Spergel, F Buchholz, E Casanova, ... genesis 32 (1), 19-26, 2002 | 466 | 2002 |
Techniques: recombinogenic engineering–new options for cloning and manipulating DNA JPP Muyrers, Y Zhang, AF Stewart Trends in biochemical sciences 26 (5), 325-331, 2001 | 345 | 2001 |
Regulation of Cre recombinase activity by the synthetic steroid RU 486 C Kellendonk, F Tronche, AP Monaghan, PO Angrand, F Stewart, ... Nucleic acids research 24 (8), 1404-1411, 1996 | 341 | 1996 |
The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program WWMP Pijnappel, D Schaft, A Roguev, A Shevchenko, H Tekotte, M Wilm, ... Genes & development 15 (22), 2991-3004, 2001 | 337 | 2001 |