Lysine 63 polyubiquitination of the nerve growth factor receptor TrkA directs internalization and signaling T Geetha, J Jiang, MW Wooten Molecular cell 20 (2), 301-312, 2005 | 332 | 2005 |
Anti-inflammatory small molecules to treat seizures and epilepsy: From bench to bedside A Dey, X Kang, J Qiu, Y Du, J Jiang Trends in pharmacological sciences 37 (6), 463-484, 2016 | 211 | 2016 |
Cyclooxygenase‐2 in epilepsy A Rojas, J Jiang, T Ganesh, MS Yang, N Lelutiu, P Gueorguieva, ... Epilepsia 55 (1), 17-25, 2014 | 200 | 2014 |
Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation J Jiang, Y Quan, T Ganesh, WA Pouliot, FE Dudek, R Dingledine Proceedings of the National Academy of Sciences 110 (9), 3591-3596, 2013 | 175 | 2013 |
Prostaglandin receptor EP2 in the crosshairs of anti-inflammation, anti-cancer, and neuroprotection J Jiang, R Dingledine Trends in pharmacological sciences 34 (7), 413-423, 2013 | 170 | 2013 |
Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2 J Jiang, T Ganesh, Y Du, Y Quan, G Serrano, M Qui, I Speigel, A Rojas, ... Proceedings of the National Academy of Sciences 109 (8), 3149-3154, 2012 | 127 | 2012 |
Cyclooxygenase-2 in glioblastoma multiforme J Qiu, Z Shi, J Jiang Drug Discovery Today 22 (1), 148-156, 2017 | 126 | 2017 |
SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity J Yan, ML Seibenhener, L Calderilla-Barbosa, MT Diaz-Meco, J Moscat, ... PloS one 8 (9), e76016, 2013 | 116 | 2013 |
Subarachnoid blood acutely induces spreading depolarizations and early cortical infarction JA Hartings, J York, CP Carroll, JM Hinzman, E Mahoney, B Krueger, ... Brain 140 (10), 2673-2690, 2017 | 112 | 2017 |
EP2 receptor signaling pathways regulate classical activation of microglia Y Quan, J Jiang, R Dingledine Journal of Biological Chemistry 288 (13), 9293-9302, 2013 | 107 | 2013 |
Role of Prostaglandin Receptor EP2 in the Regulations of Cancer Cell Proliferation, Invasion, and Inflammation J Jiang, R Dingledine Journal of Pharmacology and Experimental Therapeutics 344 (2), 360-367, 2013 | 107 | 2013 |
Therapeutic window for cyclooxygenase-2 related anti-inflammatory therapy after status epilepticus J Jiang, MS Yang, Y Quan, P Gueorguieva, T Ganesh, R Dingledine Neurobiology of Disease 76, 126-136, 2015 | 105 | 2015 |
Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor J Jiang, T Ganesh, Y Du, P Thepchatri, A Rojas, I Lewis, S Kurtkaya, L Li, ... Proceedings of the National Academy of Sciences 107 (5), 2307-2312, 2010 | 95 | 2010 |
Candidate drug targets for prevention or modification of epilepsy NH Varvel, J Jiang, R Dingledine Annual review of pharmacology and toxicology 55 (1), 229-247, 2015 | 87 | 2015 |
Posttranslational modifications and receptor-associated proteins in AMPA receptor trafficking and synaptic plasticity J Jiang, V Suppiramaniam, MW Wooten Neurosignals 15 (5), 266-282, 2006 | 82 | 2006 |
Prostaglandin E2 Signaling: Alternative Target for Glioblastoma? J Jiang, J Qiu, Q Li, Z Shi Trends in Cancer 3 (2), 75-78, 2017 | 73 | 2017 |
Cyclooxygenase-2 contributes to oxidopamine-mediated neuronal inflammation and injury via the prostaglandin E2 receptor EP2 subtype X Kang, J Qiu, Q Li, KA Bell, Y Du, DW Jung, JY Lee, J Hao, J Jiang Scientific reports 7 (1), 9459, 2017 | 55 | 2017 |
Lead optimization studies of cinnamic amide EP2 antagonists T Ganesh, J Jiang, MS Yang, R Dingledine Journal of medicinal chemistry 57 (10), 4173-4184, 2014 | 55 | 2014 |
Small-molecule inhibition of prostaglandin E receptor 2 impairs cyclooxygenase-associated malignant glioma growth. J Qiu, Q Li, KA Bell, X Yao, Y Du, E Zhang, JJ Yu, Y Yu, Z Shi, J Jiang British journal of pharmacology 176 (11), 1680-1699, 2019 | 54 | 2019 |
EP2 receptor signaling regulates microglia death Y Fu, MS Yang, J Jiang, T Ganesh, E Joe, R Dingledine Molecular pharmacology 88 (1), 161-170, 2015 | 51 | 2015 |