Glutaminolysis and fumarate accumulation integrate immunometabolic and epigenetic programs in trained immunity RJW Arts, B Novakovic, R Ter Horst, A Carvalho, S Bekkering, ... Cell metabolism 24 (6), 807-819, 2016 | 707 | 2016 |
Immunometabolic pathways in BCG-induced trained immunity RJW Arts, A Carvalho, C La Rocca, C Palma, F Rodrigues, R Silvestre, ... Cell reports 17 (10), 2562-2571, 2016 | 575 | 2016 |
Butyrate-rich colonic microenvironment is a relevant selection factor for metabolically adapted tumor cells J Serpa, F Caiado, T Carvalho, C Torre, LG Gonçalves, C Casalou, ... Journal of Biological Chemistry 285 (50), 39211-39223, 2010 | 95 | 2010 |
Identification of novel esterase-active enzymes from hot environments by use of the host bacterium Thermus thermophilus B Leis, A Angelov, M Mientus, H Li, VTT Pham, B Lauinger, P Bongen, ... Frontiers in microbiology 6, 275, 2015 | 87 | 2015 |
HNF1β drives glutathione (GSH) synthesis underlying intrinsic carboplatin resistance of ovarian clear cell carcinoma (OCCC) F Lopes-Coelho, S Gouveia-Fernandes, LG Gonçalves, C Nunes, ... Tumor Biology 37, 4813-4829, 2016 | 67 | 2016 |
Characterization of the Biosynthetic Pathway of Glucosylglycerate in the Archaeon Methanococcoides burtonii J Costa, N Empadinhas, L Gonçalves, P Lamosa, H Santos, ... Journal of bacteriology 188 (3), 1022-1030, 2006 | 49 | 2006 |
Biomaterials and bioactive natural products from marine invertebrates: From basic research to innovative applications G Romano, M Almeida, A Varela Coelho, A Cutignano, LG Gonçalves, ... Marine Drugs 20 (4), 219, 2022 | 45 | 2022 |
Joosten LAB, Matarese G, van Crevel R, Netea MG RJW Arts, A Carvalho, C La Rocca, C Palma, F Rodrigues, R Silvestre, ... Immunometabolic pathways in BCG-induced trained immunity. Cell Rep 17 (10 …, 2016 | 43 | 2016 |
A variant of the hyperthermophile Archaeoglobus fulgidus adapted to grow at high salinity LG Gonçalves, R Huber, MS da Costa, H Santos FEMS microbiology letters 218 (2), 239-244, 2003 | 41 | 2003 |
The absence of HIF-1α increases susceptibility to Leishmania donovani infection via activation of BNIP3/mTOR/SREBP-1c axis I Mesquita, C Ferreira, D Moreira, GEG Kluck, AM Barbosa, E Torrado, ... Cell Reports 30 (12), 4052-4064. e7, 2020 | 39 | 2020 |
Occurrence of 1-Glyceryl-1-myo-Inosityl Phosphate in Hyperthermophiles P Lamosa, LG Gonçalves, MV Rodrigues, LO Martins, NDH Raven, ... Applied and Environmental Microbiology 72 (9), 6169-6173, 2006 | 38 | 2006 |
Evolution of the biosynthesis of di‐myo‐inositol phosphate, a marker of adaptation to hot marine environments LG Gonçalves, N Borges, F Serra, PL Fernandes, H Dopazo, H Santos Environmental Microbiology 14 (3), 691-701, 2012 | 34 | 2012 |
A new pathway for mannitol metabolism in yeasts suggests a link to the evolution of alcoholic fermentation C Gonçalves, C Ferreira, LG Gonçalves, DL Turner, MJ Leandro, ... Frontiers in microbiology 10, 2510, 2019 | 31 | 2019 |
Biosynthetic Pathways of Inositol and Glycerol Phosphodiesters Used by the Hyperthermophile Archaeoglobus fulgidus in Stress Adaptation N Borges, LG Gonçalves, MV Rodrigues, F Siopa, R Ventura, ... Journal of bacteriology 188 (23), 8128-8135, 2006 | 30 | 2006 |
VEGFR2–mediated reprogramming of mitochondrial metabolism regulates the sensitivity of acute myeloid leukemia to chemotherapy S Nóbrega-Pereira, F Caiado, T Carvalho, I Matias, G Graça, ... Cancer Research 78 (3), 731-741, 2018 | 29 | 2018 |
Monocarboxylate transporter 1 (MCT1), a tool to stratify acute myeloid leukemia (AML) patients and a vehicle to kill cancer cells F Lopes-Coelho, C Nunes, S Gouveia-Fernandes, R Rosas, F Silva, ... Oncotarget 8 (47), 82803, 2017 | 28 | 2017 |
STAT3: FOXM1 and MCT1 drive uterine cervix carcinoma fitness to a lactate-rich microenvironment LS Silva, LG Goncalves, F Silva, G Domingues, V Maximo, J Ferreira, ... Tumor Biology 37, 5385-5395, 2016 | 28 | 2016 |
Mannosylglycerate: structural analysis of biosynthesis and evolutionary history N Borges, CD Jorge, LG Gonçalves, S Gonçalves, PM Matias, H Santos Extremophiles 18, 835-852, 2014 | 24 | 2014 |
L-threonine supplementation during colitis onset delays disease recovery J Gaifem, LG Gonçalves, RJ Dinis-Oliveira, C Cunha, A Carvalho, ... Frontiers in physiology 9, 1247, 2018 | 23 | 2018 |
Organic compatible solutes of prokaryotes that thrive in hot environments: the importance of ionic compounds for thermostabilization H Santos, P Lamosa, N Borges, LG Gonçalves, T Pais, MV Rodrigues Extremophiles handbook, 2011 | 23 | 2011 |