Cross-tissue organization of the fibroblast lineage MB Buechler, RN Pradhan, AT Krishnamurty, C Cox, AK Calviello, ... Nature 593 (7860), 575-579, 2021 | 596 | 2021 |
LRRC15+ myofibroblasts dictate the stromal setpoint to suppress tumour immunity AT Krishnamurty, JA Shyer, M Thai, V Gandham, MB Buechler, YA Yang, ... Nature 611 (7934), 148-154, 2022 | 145 | 2022 |
Histone deacetylase inhibitors increase microRNA-146a expression and enhance negative regulation of interleukin-1β signaling in osteoarthritis fibroblast-like synoviocytes JH Wang, KS Shih, YW Wu, AW Wang, CR Yang Osteoarthritis and cartilage 21 (12), 1987-1996, 2013 | 112 | 2013 |
Combinatorial genetics in liver repopulation and carcinogenesis with a in vivo CRISPR activation platform KJ Wangensteen, YJ Wang, Z Dou, AW Wang, E Mosleh‐Shirazi, ... Hepatology 68 (2), 663-676, 2018 | 76 | 2018 |
Postnatal DNA demethylation and its role in tissue maturation Y Reizel, O Sabag, Y Skversky, A Spiro, B Steinberg, D Bernstein, ... Nature communications 9 (1), 2040, 2018 | 69 | 2018 |
Targeted demethylation at the CDKN1C/p57 locus induces human β cell replication K Ou, M Yu, NG Moss, YJ Wang, AW Wang, SC Nguyen, C Jiang, ... The Journal of Clinical Investigation 129 (1), 209-214, 2019 | 57 | 2019 |
Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues VN Kapoor, S Müller, S Keerthivasan, M Brown, C Chalouni, EE Storm, ... Nature immunology 22 (5), 571-585, 2021 | 52 | 2021 |
The dynamic chromatin architecture of the regenerating liver AW Wang, YJ Wang, AM Zahm, AR Morgan, KJ Wangensteen, ... Cellular and molecular gastroenterology and hepatology 9 (1), 121-143, 2020 | 50 | 2020 |
Indole-3-ethylsulfamoylphenylacrylamides: potent histone deacetylase inhibitors with anti-inflammatory activity S Mehndiratta, YL Hsieh, YM Liu, AW Wang, HY Lee, LY Liang, S Kumar, ... European Journal of Medicinal Chemistry 85, 468-479, 2014 | 49 | 2014 |
Collapse of the hepatic gene regulatory network in the absence of FoxA factors Y Reizel, A Morgan, L Gao, Y Lan, E Manduchi, EL Waite, AW Wang, ... Genes & Development 34 (15-16), 1039-1050, 2020 | 45 | 2020 |
TRAP-seq identifies cystine/glutamate antiporter as a driver of recovery from liver injury AW Wang, KJ Wangensteen, YJ Wang, AM Zahm, NG Moss, N Erez, ... The Journal of clinical investigation 128 (6), 2297-2309, 2018 | 30 | 2018 |
In vivo tumor immune microenvironment phenotypes correlate with inflammation and vasculature to predict immunotherapy response A Sahu, K Kose, L Kraehenbuehl, C Byers, A Holland, T Tembo, ... Nature Communications 13 (1), 5312, 2022 | 29 | 2022 |
Combined PD-L1/TGFβ blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors A Castiglioni, Y Yang, K Williams, A Gogineni, RS Lane, AW Wang, ... Nature Communications 14 (1), 4703, 2023 | 13 | 2023 |
A high-content screen identifies microRNAs that regulate liver repopulation after injury in mice AM Zahm, AW Wang, YJ Wang, J Schug, KJ Wangensteen, KH Kaestner Gastroenterology 158 (4), 1044-1057. e17, 2020 | 13 | 2020 |
Phase I Study of ORIC-101, a Glucocorticoid Receptor Antagonist, in Combination with Enzalutamide in Patients with Metastatic Castration-resistant Prostate Cancer Progressing … W Abida, AW Hahn, N Shore, N Agarwal, P Sieber, MR Smith, T Dorff, ... Clinical Cancer Research 30 (6), 1111-1120, 2024 | 4 | 2024 |
Abstract P015: Biomarker results supporting selection of RP2D from a phase 1b study of ORIC-101, a glucocorticoid receptor antagonist, in combination with enzalutamide in … A Daemen, S Barkund, A Johnson, A Pankov, AW Wang, H Zhou, ... Molecular Cancer Therapeutics 20 (12_Supplement), P015-P015, 2021 | 1 | 2021 |
Cell type-specific gene expression profiling in the mouse liver AW Wang, AM Zahm, KJ Wangensteen JoVE (Journal of Visualized Experiments), e60242, 2019 | 1 | 2019 |
A high-content in vivo screen to identify microRNA epistasis in the repopulating mouse liver AM Zahm, AW Wang, YJ Wang, J Schug, KJ Wangensteen, KH Kaestner bioRxiv, 664847, 2019 | 1 | 2019 |
Innovative Approaches to Identify Regulators of Liver Regeneration AW Wang University of Pennsylvania, 2019 | 1 | 2019 |
ORIC-944, a potent and selective allosteric PRC2 inhibitor with best-in-class properties, demonstrates combination synergy with AR pathway inhibitors in prostate cancer models A Daemen, N Yuen, A Wang, A Pankov, L Ulicna, C Chen, FL Duong, ... Cancer Research 84 (6_Supplement), 6586-6586, 2024 | | 2024 |