Tumor protein 53-induced nuclear protein 1 expression is repressed by miR-155, and its restoration inhibits pancreatic tumor development M Gironella, M Seux, MJ Xie, C Cano, R Tomasini, J Gommeaux, S Garcia, ... Proceedings of the National Academy of Sciences 104 (41), 16170-16175, 2007 | 709 | 2007 |
Coronavirus RNA proofreading: molecular basis and therapeutic targeting F Robson, KS Khan, TK Le, C Paris, S Demirbag, P Barfuss, P Rocchi, ... Molecular cell 79 (5), 710-727, 2020 | 454 | 2020 |
Heat shock protein 27 increases after androgen ablation and plays a cytoprotective role in hormone-refractory prostate cancer P Rocchi, A So, S Kojima, M Signaevsky, E Beraldi, L Fazli, ... Cancer research 64 (18), 6595-6602, 2004 | 392 | 2004 |
Anticancer drug nanomicelles formed by self-assembling amphiphilic dendrimer to combat cancer drug resistance T Wei, C Chen, J Liu, C Liu, P Posocco, X Liu, Q Cheng, S Huo, Z Liang, ... Proceedings of the National Academy of Sciences 112 (10), 2978-2983, 2015 | 375 | 2015 |
Small heat shock proteins HSP27 (HspB1), αB-crystallin (HspB5) and HSP22 (HspB8) as regulators of cell death J Acunzo, M Katsogiannou, P Rocchi The international journal of biochemistry & cell biology 44 (10), 1622-1631, 2012 | 340 | 2012 |
An amphiphilic dendrimer for effective delivery of small interfering RNA and gene silencing in vitro and in vivo T Yu, X Liu, AL Bolcato‐Bellemin, Y Wang, C Liu, P Erbacher, F Qu, ... Angewandte Chemie International Edition 51 (34), 8478-8484, 2012 | 275 | 2012 |
Increased hsp27 after androgen ablation facilitates androgen-independent progression in prostate cancer via signal transducers and activators of transcription 3–mediated … P Rocchi, E Beraldi, S Ettinger, L Fazli, RL Vessella, C Nelson, M Gleave Cancer research 65 (23), 11083-11093, 2005 | 262 | 2005 |
Hsp27 knockdown using nucleotide-based therapies inhibit tumor growth and enhance chemotherapy in human bladder cancer cells M Kamada, A So, M Muramaki, P Rocchi, E Beraldi, M Gleave Molecular cancer therapeutics 6 (1), 299-308, 2007 | 224 | 2007 |
Highly effective NK cells are associated with good prognosis in patients with metastatic prostate cancer C Pasero, G Gravis, S Granjeaud, M Guerin, J Thomassin-Piana, ... Oncotarget 6 (16), 14360, 2015 | 214 | 2015 |
Adaptive amphiphilic dendrimer‐based nanoassemblies as robust and versatile siRNA delivery systems X Liu, J Zhou, T Yu, C Chen, Q Cheng, K Sengupta, Y Huang, H Li, C Liu, ... Angewandte Chemie International Edition 53 (44), 11822-11827, 2014 | 210 | 2014 |
Inherent and tumor-driven immune tolerance in the prostate microenvironment impairs natural killer cell antitumor activity C Pasero, G Gravis, M Guerin, S Granjeaud, J Thomassin-Piana, ... Cancer research 76 (8), 2153-2165, 2016 | 200 | 2016 |
A dual targeting dendrimer-mediated siRNA delivery system for effective gene silencing in cancer therapy Y Dong, T Yu, L Ding, E Laurini, Y Huang, M Zhang, Y Weng, S Lin, ... Journal of the American Chemical Society 140 (47), 16264-16274, 2018 | 177 | 2018 |
Small interference RNA targeting heat‐shock protein 27 inhibits the growth of prostatic cell lines and induces apoptosis via caspase‐3 activation in vitro P Rocchi, P Jugpal, A So, S Sinneman, S Ettinger, L Fazli, C Nelson, ... BJU international 98 (5), 1082-1089, 2006 | 171 | 2006 |
Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E C Andrieu, D Taieb, V Baylot, S Ettinger, P Soubeyran, A De-Thonel, ... Oncogene 29 (13), 1883-1896, 2010 | 165 | 2010 |
PAMAM dendrimers mediate siRNA delivery to target Hsp27 and produce potent antiproliferative effects on prostate cancer cells X Liu, P Rocchi, F Qu, S Zheng, Z Liang, M Gleave, J Iovanna, L Peng ChemMedChem 4 (8), 1302-1310, 2009 | 155 | 2009 |
Heat shock protein 27 phosphorylation state is associated with cancer progression M Katsogiannou, C Andrieu, P Rocchi Frontiers in genetics 5, 346, 2014 | 136 | 2014 |
Expression of adrenomedullin and peptide amidation activity in human prostate cancer and in human prostate cancer cell lines P Rocchi, F Boudouresque, AJ Zamora, X Muracciole, E Lechevallier, ... Cancer research 61 (3), 1196-1206, 2001 | 136 | 2001 |
Efficient delivery of sticky siRNA and potent gene silencing in a prostate cancer model using a generation 5 triethanolamine-core PAMAM dendrimer X Liu, C Liu, E Laurini, P Posocco, S Pricl, F Qu, P Rocchi, L Peng Molecular Pharmaceutics 9 (3), 470-481, 2012 | 130 | 2012 |
OGX-427 inhibits tumor progression and enhances gemcitabine chemotherapy in pancreatic cancer V Baylot, C Andrieu, M Katsogiannou, D Taieb, S Garcia, S Giusiano, ... Cell death & disease 2 (10), e221-e221, 2011 | 127 | 2011 |
A novel antisense oligonucleotide inhibiting several antiapoptotic Bcl-2 family members induces apoptosis and enhances chemosensitivity in androgen-independent human prostate … K Yamanaka, P Rocchi, H Miyake, L Fazli, B Vessella, ... Molecular cancer therapeutics 4 (11), 1689-1698, 2005 | 127 | 2005 |