Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice ED Mock, M Mustafa, O Gunduz-Cinar, R Cinar, GN Petrie, V Kantae, X Di, ... Nature chemical biology 16 (6), 667-675, 2020 | 72 | 2020 |
Binding studies reveal phospholipid specificity and its role in the calcium-dependent mechanism of action of daptomycin I Kotsogianni, TM Wood, FM Alexander, SA Cochrane, NI Martin ACS Infectious Diseases 7 (9), 2612-2619, 2021 | 33 | 2021 |
Dissecting the binding interactions of teixobactin with the bacterial cell‐wall precursor lipid II S Chiorean, I Antwi, DW Carney, I Kotsogianni, AM Giltrap, FM Alexander, ... ChemBioChem 21 (6), 789-792, 2020 | 29 | 2020 |
Cephalosporin Prodrug Inhibitors Overcome Metallo‐β‐Lactamase Driven Antibiotic Resistance MJ van Haren, KHME Tehrani, I Kotsogianni, N Wade, NC Brüchle, ... Chemistry–A European Journal 27 (11), 3806-3811, 2021 | 19 | 2021 |
Polymyxin stereochemistry and its role in antibacterial activity and outer membrane disruption CJ Slingerland, I Kotsogianni, CMJ Wesseling, NI Martin ACS Infectious Diseases 8 (12), 2396-2404, 2022 | 11 | 2022 |
Structure–Activity Relationship Studies of Pyrimidine-4-Carboxamides as Inhibitors of N-Acylphosphatidylethanolamine Phospholipase D ED Mock, I Kotsogianni, WPF Driever, CS Fonseca, JM Vooijs, H den Dulk, ... Journal of Medicinal Chemistry 64 (1), 481-515, 2020 | 10 | 2020 |
Dual targeting of the class V lanthipeptide antibiotic cacaoidin JP Deisinger, M Arts, I Kotsogianni, JS Puls, F Grein, FJ Ortiz-López, ... Iscience 26 (4), 2023 | 9 | 2023 |
Chemical proteomics reveals antibiotic targets of oxadiazolones in MRSA AT Bakker, I Kotsogianni, L Mirenda, VM Straub, M Avalos, ... Journal of the American Chemical Society 145 (2), 1136-1143, 2022 | 9 | 2022 |
In vivo biodistribution of kinetically stable Pt 2 L 4 nanospheres that show anti-cancer activity EO Bobylev, RA Knol, S Mathew, DA Poole, I Kotsogianni, NI Martin, ... Chemical Science 14 (25), 6943-6952, 2023 | 8 | 2023 |
A β-hairpin epitope as novel structural requirement for protein arginine rhamnosylation L Yakovlieva, TM Wood, J Kemmink, I Kotsogianni, F Koller, J Lassak, ... Chemical Science 12 (4), 1560-1567, 2021 | 5 | 2021 |
A classic antibiotic reimagined: Rationally designed bacitracin variants exhibit potent activity against vancomycin-resistant pathogens NP Buijs, HC Vlaming, I Kotsogianni, M Arts, J Willemse, Y Duan, ... Proceedings of the National Academy of Sciences 121 (29), e2315310121, 2024 | | 2024 |
Synthesis and evaluation of carbapenem/metallo‐β‐lactamase inhibitor conjugates ML Gao, I Kotsogianni, F Skoulikopoulou, NC Brüchle, P Innocenti, ... ChemMedChem, e202400302, 2024 | | 2024 |
Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria AT Bakker, I Kotsogianni, M Avalos, JM Punt, B Liu, D Piermarini, ... Nature Chemistry, 1-11, 2024 | | 2024 |