| Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B DAE Cross, DR Alessi, P Cohen, M Andjelkovich, BA Hemmings Nature 378 (6559), 785-789, 1995 | 6627 | 1995 |
| PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo DR Alessi, A Cuenda, P Cohen, DT Dudley, AR Saltiel Journal of Biological Chemistry 270 (46), 27489-27494, 1995 | 4134 | 1995 |
| Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα DR Alessi, SR James, CP Downes, AB Holmes, PRJ Gaffney, CB Reese, ... Current biology 7 (4), 261-269, 1997 | 3939 | 1997 |
| Mechanism of activation of protein kinase B by insulin and IGF‐1. DR Alessi, M Andjelkovic, B Caudwell, P Cron, N Morrice, P Cohen, ... The EMBO journal 15 (23), 6541-6551, 1996 | 3905 | 1996 |
| The selectivity of protein kinase inhibitors: a further update J Bain, L Plater, M Elliott, N Shpiro, CJ Hastie, H Mclauchlan, I Klevernic, ... Biochemical Journal 408 (3), 297-315, 2007 | 3013 | 2007 |
| Metformin and reduced risk of cancer in diabetic patients JMM Evans, LA Donnelly, AM Emslie-Smith, DR Alessi, AD Morris Bmj 330 (7503), 1304-1305, 2005 | 2981 | 2005 |
| The PI3K–PDK1 connection: more than just a road to PKB B Vanhaesebroeck, DR Alessi Biochemical Journal 346 (3), 561-576, 2000 | 2235 | 2000 |
| Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade SA Hawley, J Boudeau, JL Reid, KJ Mustard, L Udd, TP Mäkelä, ... Journal of biology 2, 1-16, 2003 | 2083 | 2003 |
| The nuts and bolts of AGC protein kinases LR Pearce, D Komander, DR Alessi Nature reviews Molecular cell biology 11 (1), 9-22, 2010 | 1574 | 2010 |
| LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1 JM Lizcano, O Göransson, R Toth, M Deak, NA Morrice, J Boudeau, ... The EMBO journal 23 (4), 833-843, 2004 | 1573 | 2004 |
| PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? MA Lawlor, DR Alessi Journal of cell science 114 (16), 2903-2910, 2001 | 1521 | 2001 |
| Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1 JA Le Good, WH Ziegler, DB Parekh, DR Alessi, P Cohen, PJ Parker Science 281 (5385), 2042-2045, 1998 | 1437 | 1998 |
| Role of translocation in the activation and function of protein kinase B M Andjelkovic, DR Alessi, R Meier, A Fernandez, NJC Lamb, M Frech, ... Journal of Biological Chemistry 272 (50), 31515-31524, 1997 | 1375 | 1997 |
| New users of metformin are at low risk of incident cancer: a cohort study among people with type 2 diabetes G Libby, LA Donnelly, PT Donnan, DR Alessi, AD Morris, JMM Evans Diabetes care 32 (9), 1620-1625, 2009 | 1352 | 2009 |
| Mitogen‐and stress‐activated protein kinase‐1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB M Deak, AD Clifton, JM Lucocq, DR Alessi The EMBO journal, 1998 | 1278 | 1998 |
| Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on … BT Navé, DM Ouwens, DJ Withers, DR Alessi, PR SHEPHERD Biochemical Journal 344 (2), 427-431, 1999 | 1223 | 1999 |
| mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum-and glucocorticoid-induced protein kinase 1 (SGK1) JM García-Martínez, DR Alessi Biochemical Journal 416 (3), 375-385, 2008 | 1114 | 2008 |
| PDK1, the master regulator of AGC kinase signal transduction A Mora, D Komander, DMF van Aalten, DR Alessi Seminars in cell & developmental biology 15 (2), 161-170, 2004 | 1027 | 2004 |
| Mechanism of activation and function of protein kinase B DR Alessi, P Cohen Current opinion in genetics & development 8 (1), 55-62, 1998 | 1024 | 1998 |
| 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase DR Alessi, M Deak, A Casamayor, FB Caudwell, N Morrice, DG Norman, ... Current biology 7 (10), 776-789, 1997 | 996 | 1997 |
Philip CohenMRC Protein Phosphorylation Unit, University of Dundee Scotland在 dundee.ac.uk 的电子邮件经过验证
