Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma EE Bar, A Chaudhry, A Lin, X Fan, K Schreck, W Matsui, S Piccirillo, ... Stem cells 25 (10), 2524-2533, 2007 | 766 | 2007 |
Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres EE Bar, A Lin, V Mahairaki, W Matsui, CG Eberhart The American journal of pathology 177 (3), 1491-1502, 2010 | 417 | 2010 |
Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma EE Bar, A Lin, T Tihan, PC Burger, CG Eberhart Journal of Neuropathology & Experimental Neurology 67 (9), 878-887, 2008 | 298 | 2008 |
A polymeric nanoparticle formulation of curcumin inhibits growth, clonogenicity and stem-like fraction in malignant brain tumors KJ Lim, S Bisht, EE Bar, A Maitra, CG Eberhart Cancer biology & therapy 11 (5), 464-473, 2011 | 294 | 2011 |
BRAF activation induces transformation and then senescence in human neural stem cells: a pilocytic astrocytoma model EH Raabe, KS Lim, JM Kim, A Meeker, X Mao, G Nikkhah, J Maciaczyk, ... Clinical Cancer Research 17 (11), 3590-3599, 2011 | 205 | 2011 |
The Notch target Hes1 directly modulates Gli1 expression and Hedgehog signaling: a potential mechanism of therapeutic resistance KC Schreck, P Taylor, L Marchionni, V Gopalakrishnan, EE Bar, N Gaiano, ... Clinical cancer research 16 (24), 6060-6070, 2010 | 201 | 2010 |
BRAF Alterations in Primary Glial and Glioneuronal Neoplasms of the Central Nervous System With Identification of 2 Novel KIAA1549: BRAF Fusion Variants A Lin, FJ Rodriguez, MA Karajannis, SC Williams, G Legault, D Zagzag, ... Journal of Neuropathology & Experimental Neurology 71 (1), 66-72, 2012 | 178 | 2012 |
Glioblastoma, cancer stem cells and hypoxia EE Bar Brain Pathology 21 (2), 119-129, 2011 | 149 | 2011 |
Hedgehog signaling promotes medulloblastoma survival via BclII EE Bar, A Chaudhry, MH Farah, CG Eberhart The American journal of pathology 170 (1), 347-355, 2007 | 142 | 2007 |
Targetable T-type calcium channels drive glioblastoma Y Zhang, N Cruickshanks, F Yuan, B Wang, M Pahuski, J Wulfkuhle, ... Cancer research 77 (13), 3479-3490, 2017 | 115 | 2017 |
Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo NH Boyd, K Walker, J Fried, JR Hackney, PC McDonald, GA Benavides, ... JCI insight 2 (24), 2017 | 112 | 2017 |
ZEB1 promotes invasion in human fetal neural stem cells and hypoxic glioma neurospheres UD Kahlert, AK Suwala, EH Raabe, FA Siebzehnrubl, MJ Suarez, BA Orr, ... Brain pathology 25 (6), 724-732, 2015 | 78 | 2015 |
Notch signaling promotes growth and invasion in uveal melanoma L Asnaghi, KB Ebrahimi, KC Schreck, EE Bar, ML Coonfield, WR Bell, ... Clinical cancer research 18 (3), 654-665, 2012 | 77 | 2012 |
MicroRNA profiling in pediatric pilocytic astrocytoma reveals biologically relevant targets, including PBX3, NFIB, and METAP2 CY Ho, E Bar, C Giannini, L Marchionni, MA Karajannis, D Zagzag, ... Neuro-oncology 15 (1), 69-82, 2013 | 76 | 2013 |
Inhibition of monocarboxylate transporter-4 depletes stem-like glioblastoma cells and inhibits HIF transcriptional response in a lactate-independent manner KS Lim, KJ Lim, AC Price, BA Orr, CG Eberhart, EE Bar Oncogene 33 (35), 4433-4441, 2014 | 73 | 2014 |
Hypoxia promotes uveal melanoma invasion through enhanced Notch and MAPK activation L Asnaghi, MH Lin, KS Lim, KJ Lim, A Tripathy, M Wendeborn, SL Merbs, ... PloS one 9 (8), e105372, 2014 | 64 | 2014 |
Prolonged Inhibition of Glioblastoma Xenograft Initiation and Clonogenic Growth following In Vivo Notch Blockade Q Chu, BA Orr, S Semenkow, EE Bar, CG Eberhart Clinical Cancer Research 19 (12), 3224-3233, 2013 | 64 | 2013 |
Targeting BCL-xL improves the efficacy of bromodomain and extra-terminal protein inhibitors in triple-negative breast cancer by eliciting the death of senescent cells SS Gayle, JM Sahni, BM Webb, KL Weber-Bonk, MS Shively, R Spina, ... Journal of Biological Chemistry 294 (3), 875-886, 2019 | 60 | 2019 |
Long-term, stable differentiation of human embryonic stem cell-derived neural precursors grafted into the adult mammalian neostriatum I Nasonkin, V Mahairaki, L Xu, G Hatfield, BJ Cummings, C Eberhart, ... Stem cells 27 (10), 2414-2426, 2009 | 60 | 2009 |
Disruption of the monocarboxylate transporter-4-basigin interaction inhibits the hypoxic response, proliferation, and tumor progression DM Voss, R Spina, DL Carter, KS Lim, CJ Jeffery, EE Bar Scientific reports 7 (1), 4292, 2017 | 53 | 2017 |