Lipid nanoparticle-delivered chemically modified mRNA restores chloride secretion in cystic fibrosis E Robinson, KD MacDonald, K Slaughter, M McKinney, S Patel, C Sun, ... Molecular Therapy 26 (8), 2034-2046, 2018 | 245 | 2018 |
Engineering lipid nanoparticles for enhanced intracellular delivery of mRNA through inhalation J Kim, A Jozic, Y Lin, Y Eygeris, E Bloom, X Tan, C Acosta, ... ACS nano 16 (9), 14792-14806, 2022 | 92 | 2022 |
Cystic Fibrosis Transmembrane Regulator Protein Mutations: ‘Class’ Opportunity for Novel Drug Innovation KD MacDonald, KR McKenzie, PL Zeitlin Pediatric drugs 9, 1-10, 2007 | 64 | 2007 |
A simple method of mouse lung intubation S Das, K MacDonald, HYS Chang, W Mitzner JoVE (Journal of Visualized Experiments), e50318, 2013 | 63 | 2013 |
An improved simple method of mouse lung intubation KD MacDonald, HYS Chang, W Mitzner Journal of applied physiology 106 (3), 984-987, 2009 | 61 | 2009 |
Spontaneous desaturations in intubated very low birth weight infants with acute and chronic lung disease M Durand, C McEvoy, K MacDonald Pediatric pulmonology 13 (3), 136-142, 1992 | 56 | 1992 |
The effect of extended continuous positive airway pressure on changes in lung volumes in stable premature infants: a randomized controlled trial R Lam, D Schilling, B Scottoline, A Platteau, M Niederhausen, KC Lund, ... The Journal of pediatrics 217, 66-72. e1, 2020 | 52 | 2020 |
Lubiprostone activates CFTR, but not ClC-2, via the prostaglandin receptor (EP4) Y Norimatsu, AR Moran, KD MacDonald Biochemical and biophysical research communications 426 (3), 374-379, 2012 | 49 | 2012 |
Lubiprostone activates non-CFTR-dependent respiratory epithelial chloride secretion in cystic fibrosis mice KD MacDonald, KR McKenzie, MJ Henderson, CE Hawkins, N Vij, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 295 (5 …, 2008 | 45 | 2008 |
Inhaled mRNA therapy for treatment of cystic fibrosis: Interim results of a randomized, double‐blind, placebo‐controlled phase 1/2 clinical study SM Rowe, JB Zuckerman, D Dorgan, J Lascano, K McCoy, M Jain, ... Journal of Cystic Fibrosis 22 (4), 656-664, 2023 | 37 | 2023 |
Oral antimicrobial use in outpatient cystic fibrosis pulmonary exacerbation management: a single‐center experience EC Briggs, T Nguyen, MA Wall, KD MacDonald The clinical respiratory journal 6 (1), 56-64, 2012 | 33 | 2012 |
Spiperone, identified through compound screening, activates calcium-dependent chloride secretion in the airway L Liang, K MacDonald, EM Schwiebert, PL Zeitlin, WB Guggino American Journal of Physiology-Cell Physiology 296 (1), C131-C141, 2009 | 28 | 2009 |
Maternal high‐fat diet in mice leads to innate airway hyperresponsiveness in the adult offspring KD MacDonald, AR Moran, AJ Scherman, CT McEvoy, AS Platteau Physiological reports 5 (5), e13082, 2017 | 24 | 2017 |
Aqueous cigarette smoke extract induces a voltage-dependent inhibition of CFTR expressed in Xenopus oocytes AR Moran, Y Norimatsu, DC Dawson, KD MacDonald American Journal of Physiology-Lung Cellular and Molecular Physiology 306 (3 …, 2014 | 22 | 2014 |
Engineered mutant α-ENaC subunit mRNA delivered by lipid nanoparticles reduces amiloride currents in cystic fibrosis–based cell and mice models A Mukherjee, KD MacDonald, J Kim, MI Henderson, Y Eygeris, G Sahay Science advances 6 (47), eabc5911, 2020 | 20 | 2020 |
Effect of vitamin C supplementation for pregnant smokers on offspring airway function and wheeze at age 5 years: follow-up of a randomized clinical trial CT McEvoy, LE Shorey-Kendrick, K Milner, J Harris, B Vuylsteke, ... JAMA pediatrics 177 (1), 16-24, 2023 | 18 | 2023 |
Maternal body mass index before pregnancy is associated with increased bronchodilator dispensing in early childhood: a cross‐sectional study KD MacDonald, KK Vesco, KL Funk, J Donovan, T Nguyen, Z Chen, ... Pediatric pulmonology 51 (8), 803-811, 2016 | 16 | 2016 |
Tracheal bronchus in a 6-month-old infant identified by CT with three-dimensional airway reconstruction WA Gower, SA McGrath-Morrow, KD MacDonald, EK Fishman Thorax 63 (1), 93-94, 2008 | 12 | 2008 |
Volume and pressure modes of mechanical ventilation in pediatric patients. KD MacDonald, SR Johnson Respiratory Care Clinics of North America 2 (4), 607-618, 1996 | 12 | 1996 |
Cost effectiveness of vitamin c supplementation for pregnant smokers to improve offspring lung function at birth and reduce childhood wheeze/asthma L Yieh, CT McEvoy, SW Hoffman, AB Caughey, KD MacDonald, ... Journal of Perinatology 38 (7), 820-827, 2018 | 10 | 2018 |