Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases R Hoessel, S Leclerc, JA Endicott, MEM Nobel, A Lawrie, P Tunnah, ... Nature cell biology 1 (1), 60-67, 1999 | 1035 | 1999 |
Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease: A PROPERTY COMMON TO MOST … S Leclerc, M Garnier, R Hoessel, D Marko, JA Bibb, GL Snyder, ... Journal of Biological Chemistry 276 (1), 251-260, 2001 | 928 | 2001 |
The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth-factor receptor S Meiers, M Kemény, U Weyand, R Gastpar, E von Angerer, D Marko Journal of agricultural and food chemistry 49 (2), 958-962, 2001 | 361 | 2001 |
Proposal of a comprehensive definition of modified and other forms of mycotoxins including “masked” mycotoxins M Rychlik, HU Humpf, D Marko, S Dänicke, A Mally, F Berthiller, H Klaffke, ... Mycotoxin research 30, 197-205, 2014 | 355 | 2014 |
Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells D Marko, S Schätzle, A Friedel, A Genzlinger, H Zankl, L Meijer, ... British journal of cancer 84 (2), 283-289, 2001 | 274 | 2001 |
Nitrate and nitrite in the diet: how to assess their benefit and risk for human health M Habermeyer, A Roth, S Guth, P Diel, KH Engel, B Epe, P Fürst, V Heinz, ... Molecular nutrition & food research 59 (1), 106-128, 2015 | 267 | 2015 |
Coffee constituents as modulators of Nrf2 nuclear translocation and ARE (EpRE)-dependent gene expression U Boettler, K Sommerfeld, N Volz, G Pahlke, N Teller, V Somoza, R Lang, ... The Journal of nutritional biochemistry 22 (5), 426-440, 2011 | 243 | 2011 |
Risk assessment of aflatoxins in food EFSA Panel on Contaminants in the Food Chain (CONTAM), D Schrenk, ... EFSA journal 18 (3), e06040, 2020 | 227 | 2020 |
Alternariol acts as a topoisomerase poison, preferentially affecting the IIα isoform M Fehr, G Pahlke, J Fritz, MO Christensen, F Boege, M Altemöller, ... Molecular nutrition & food research 53 (4), 441-451, 2009 | 217 | 2009 |
Inhibitor binding to active and inactive CDK2: the crystal structure of CDK2-cyclin A/indirubin-5-sulphonate TG Davies, P Tunnah, L Meijer, D Marko, G Eisenbrand, JA Endicott, ... Structure 9 (5), 389-397, 2001 | 188 | 2001 |
Cellular uptake of platinum nanoparticles in human colon carcinoma cells and their impact on cellular redox systems and DNA integrity J Pelka, H Gehrke, M Esselen, M Türk, M Crone, S Bräse, T Muller, ... Chemical research in toxicology 22 (4), 649-659, 2009 | 185 | 2009 |
TDP1 overexpression in human cells counteracts DNA damage mediated by topoisomerases I and II HU Barthelmes, M Habermeyer, MO Christensen, C Mielke, H Interthal, ... Journal of Biological Chemistry 279 (53), 55618-55625, 2004 | 172 | 2004 |
Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs? S Thomasset, N Teller, H Cai, D Marko, DP Berry, WP Steward, ... Cancer chemotherapy and pharmacology 64, 201-211, 2009 | 168 | 2009 |
Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses S Guth, S Hüser, A Roth, G Degen, P Diel, K Edlund, G Eisenbrand, ... Archives of toxicology 94, 1375-1415, 2020 | 167 | 2020 |
Platinum nanoparticles and their cellular uptake and DNA platination at non-cytotoxic concentrations H Gehrke, J Pelka, CG Hartinger, H Blank, F Bleimund, R Schneider, ... Archives of toxicology 85, 799-812, 2011 | 159 | 2011 |
Structure–Activity Relationships of Targeted RuII(η6-p-Cymene) Anticancer Complexes with Flavonol-Derived Ligands A Kurzwernhart, W Kandioller, S Bächler, C Bartel, S Martic, ... Journal of Medicinal Chemistry 55 (23), 10512-10522, 2012 | 158 | 2012 |
Targeting the DNA-topoisomerase complex in a double-strike approach with a topoisomerase inhibiting moiety and covalent DNA binder A Kurzwernhart, W Kandioller, C Bartel, S Bächler, R Trondl, ... Chemical Communications 48 (40), 4839-4841, 2012 | 156 | 2012 |
Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization R Gastpar, M Goldbrunner, D Marko, E Von Angerer Journal of medicinal chemistry 41 (25), 4965-4972, 1998 | 154 | 1998 |
The substitution pattern of anthocyanidins affects different cellular signaling cascades regulating cell proliferation D Marko, N Puppel, Z Tjaden, S Jakobs, G Pahlke Molecular nutrition & food research 48 (4), 318-325, 2004 | 149 | 2004 |
Inhibitors of Leishmania mexicana CRK3 Cyclin-Dependent Kinase: Chemical Library Screen and Antileishmanial Activity KM Grant, MH Dunion, V Yardley, AL Skaltsounis, D Marko, G Eisenbrand, ... Antimicrobial agents and chemotherapy 48 (8), 3033-3042, 2004 | 129 | 2004 |