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Samah El Ghamrasni
Samah El Ghamrasni
postdoctoral fellow
在 utoronto.ca 的电子邮件经过验证
标题
引用次数
引用次数
年份
Dysregulation of the mevalonate pathway promotes transformation
JW Clendening, A Pandyra, PC Boutros, SE Ghamrasni, F Khosravi, ...
Proceedings of the National Academy of Sciences 107 (34), 15051-15056, 2010
4382010
Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer
L Li, MJ Halaby, A Hakem, R Cardoso, S El Ghamrasni, S Harding, ...
Journal of Experimental Medicine 207 (5), 983-997, 2010
1352010
Systemic ceramide accumulation leads to severe and varied pathological consequences
AM Alayoubi, JCM Wang, BCY Au, S Carpentier, V Garcia, S Dworski, ...
EMBO molecular medicine 5 (6), 827-842, 2013
1132013
RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks
M Bohgaki, T Bohgaki, S El Ghamrasni, T Srikumar, G Maire, S Panier, ...
Proceedings of the National Academy of Sciences 110 (52), 20982-20987, 2013
1092013
Pan-cancer analysis of longitudinal metastatic tumors reveals genomic alterations and immune landscape dynamics associated with pembrolizumab sensitivity
SY Cindy Yang, SC Lien, BX Wang, DL Clouthier, Y Hanna, I Cirlan, ...
Nature communications 12 (1), 5137, 2021
742021
Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape
JP Bruce, KF To, VWY Lui, GTY Chung, YY Chan, CM Tsang, KY Yip, ...
Nature communications 12 (1), 4193, 2021
642021
RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors
PS Patel, KJ Abraham, KKN Guturi, MJ Halaby, Z Khan, L Palomero, B Ho, ...
The Journal of clinical investigation 131 (3), 2021
472021
RNF168 and USP10 regulate topoisomerase IIα function via opposing effects on its ubiquitylation
KKN Guturi, M Bohgaki, T Bohgaki, T Srikumar, D Ng, R Kumareswaran, ...
Nature communications 7 (1), 12638, 2016
462016
Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer
S El Ghamrasni, A Pamidi, MJ Halaby, M Bohgaki, R Cardoso, L Li, ...
PLoS genetics 7 (5), e1001385, 2011
242011
Synergistic interaction of Rnf8 and p53 in the protection against genomic instability and tumorigenesis
MJ Halaby, A Hakem, L Li, S El Ghamrasni, S Venkatesan, PM Hande, ...
PLoS genetics 9 (1), e1003259, 2013
232013
Caspase-8 is essential for maintaining chromosomal stability and suppressing B-cell lymphomagenesis
A Hakem, S El Ghamrasni, G Maire, B Lemmers, J Karaskova, ...
Blood, The Journal of the American Society of Hematology 119 (15), 3495-3502, 2012
222012
IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interaction with the AITL microenvironment
J Leca, F Lemonnier, C Meydan, J Foox, S El Ghamrasni, DL Mboumba, ...
Cancer Cell 41 (2), 323-339. e10, 2023
202023
The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor–resistant ER+ breast cancer with mitotic aberrations
I Soria-Bretones, KL Thu, J Silvester, J Cruickshank, S El Ghamrasni, ...
Science Advances 8 (36), eabq4293, 2022
202022
Loss of epigenetic regulation disrupts lineage integrity, induces aberrant alveogenesis, and promotes breast cancer
E Langille, KN Al-Zahrani, Z Ma, M Liang, L Uuskula-Reimand, R Espin, ...
Cancer discovery 12 (12), 2930-2953, 2022
192022
Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression
S El Ghamrasni, R Cardoso, MJ Halaby, D Zeegers, S Harding, ...
Oncogene 34 (14), 1780-1789, 2015
182015
Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor
R Quevedo, A Spreafico, J Bruce, A Danesh, S El Ghamrasni, A Giesler, ...
Genome Medicine 12, 1-15, 2020
132020
Rad54 and Mus81 cooperation promotes DNA damage repair and restrains chromosome missegregation
S El Ghamrasni, R Cardoso, L Li, KKN Guturi, VA Bjerregaard, Y Liu, ...
Oncogene 35 (37), 4836-4845, 2016
122016
RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells
R Krishnan, M Lapierre, B Gautreau, KCJ Nixon, S El Ghamrasni, ...
Nucleic Acids Research 51 (19), 10484-10505, 2023
42023
Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer
S El Ghamrasni, R Quevedo, J Hawley, P Mazrooei, Y Hanna, I Cirlan, ...
Molecular Cancer Research 20 (1), 102-113, 2022
32022
Topoisomerase 1 inhibition in MYC-driven cancer promotes aberrant R-loop accumulation to induce synthetic lethality
P Lin, C Lourenco, J Cruickshank, L Palomero, JE Van Leeuwen, ...
Cancer Research 83 (24), 4015-4029, 2023
22023
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