Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR K Jadhav, Y Xu, Y Xu, Y Li, J Xu, Y Zhu, L Adorini, YK Lee, T Kasumov, ... Molecular metabolism 9, 131-140, 2018 | 113 | 2018 |
Macrophage miR-34a is a key regulator of cholesterol efflux and atherosclerosis Y Xu, Y Xu, Y Zhu, H Sun, C Juguilon, F Li, D Fan, L Yin, Y Zhang Molecular Therapy 28 (1), 202-216, 2020 | 108 | 2020 |
Hepatocyte nuclear factor 4α prevents the Steatosis‐to‐NASH progression by regulating p53 and bile acid signaling (in mice) Y Xu, Y Zhu, S Hu, Y Xu, D Stroup, X Pan, FC Bawa, S Chen, R Gopoju, ... Hepatology 73 (6), 2251-2265, 2021 | 63 | 2021 |
Mouse models of atherosclerosis in translational research I Ilyas, PJ Little, Z Liu, Y Xu, D Kamato, BC Berk, J Weng, S Xu Trends in Pharmacological Sciences 43 (11), 920-939, 2022 | 59 | 2022 |
Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism Y Xu, Y Li, K Jadhav, X Pan, Y Zhu, S Hu, S Chen, L Chen, Y Tang, ... Nature metabolism 3 (1), 59-74, 2021 | 58 | 2021 |
Hepatocyte miR-34a is a key regulator in the development and progression of non-alcoholic fatty liver disease Y Xu, Y Zhu, S Hu, X Pan, FC Bawa, HH Wang, DQH Wang, L Yin, ... Molecular metabolism 51, 101244, 2021 | 57 | 2021 |
Prenatal caffeine exposure increases the susceptibility to non-alcoholic fatty liver disease in female offspring rats via activation of GR-C/EBPα-SIRT1 pathway S Hu, L Xia, H Luo, Y Xu, H Yu, D Xu, H Wang Toxicology 417, 23-34, 2019 | 39 | 2019 |
Lipocalin‐2 protects against diet‐induced nonalcoholic fatty liver disease by targeting hepatocytes Y Xu, Y Zhu, K Jadhav, Y Li, H Sun, L Yin, T Kasumov, X Chen, Y Zhang Hepatology Communications 3 (6), 763-775, 2019 | 35 | 2019 |
Farnesoid X receptor activation by obeticholic acid elevates liver low-density lipoprotein receptor expression by mRNA stabilization and reduces plasma low-density lipoprotein … AB Singh, B Dong, FB Kraemer, Y Xu, Y Zhang, J Liu Arteriosclerosis, thrombosis, and vascular biology 38 (10), 2448-2459, 2018 | 31 | 2018 |
Hepatic overexpression of methionine sulfoxide reductase A reduces atherosclerosis in apolipoprotein E-deficient mice YY Xu, F Du, B Meng, GH Xie, J Cao, D Fan, H Yu Journal of lipid research 56 (10), 1891-1900, 2015 | 30 | 2015 |
Hepatic forkhead box protein A3 regulates ApoA-I (apolipoprotein AI) expression, cholesterol efflux, and atherogenesis Y Li, Y Xu, K Jadhav, Y Zhu, L Yin, Y Zhang Arteriosclerosis, thrombosis, and vascular biology 39 (8), 1574-1587, 2019 | 29 | 2019 |
Global inactivation of carboxylesterase 1 (Ces1/Ces1g) protects against atherosclerosis in Ldlr−/− mice J Xu, Y Xu, Y Xu, L Yin, Y Zhang Scientific reports 7 (1), 17845, 2017 | 27 | 2017 |
Hepatocyte-specific expression of human carboxylesterase 2 attenuates nonalcoholic steatohepatitis in mice Y Xu, X Pan, S Hu, Y Zhu, F Cassim Bawa, Y Li, L Yin, Y Zhang American Journal of Physiology-Gastrointestinal and Liver Physiology 320 (2 …, 2021 | 26 | 2021 |
Narirutin activates TFEB (transcription factor EB) to protect against Acetaminophen-induced liver injury by targeting PPP3/calcineurin Z Fang, Y Xu, G Liu, Q Shao, X Niu, W Tai, T Shen, M Fan, M Chen, L Lei, ... Autophagy 19 (8), 2240-2256, 2023 | 24 | 2023 |
Mechanism of the switch from NO to H2O2 in endothelium-dependent vasodilation in diabetes C Juguilon, Z Wang, Y Wang, M Enrick, A Jamaiyar, Y Xu, J Gadd, ... Basic research in cardiology 117 (1), 2, 2022 | 23 | 2022 |
Hepatocytic activating transcription factor 3 protects against steatohepatitis via hepatocyte nuclear factor 4α Y Xu, S Hu, K Jadhav, Y Zhu, X Pan, FC Bawa, L Yin, Y Zhang Diabetes 70 (11), 2506-2517, 2021 | 23 | 2021 |
Identification of a novel function of hepatic long-chain acyl-CoA synthetase-1 (ACSL1) in bile acid synthesis and its regulation by bile acid-activated farnesoid X receptor AB Singh, B Dong, Y Xu, Y Zhang, J Liu Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 22 | 2019 |
BAF60a deficiency in macrophage promotes diet-induced obesity and metabolic inflammation Q Kong, J Zou, Z Zhang, R Pan, ZY Zhang, S Han, Y Xu, Y Gao, ZX Meng Diabetes 71 (10), 2136-2152, 2022 | 21 | 2022 |
PEP-1-MsrA ameliorates inflammation and reduces atherosclerosis in apolipoprotein E deficient mice Y Wu, G Xie, Y Xu, L Ma, C Tong, D Fan, F Du, H Yu Journal of Translational Medicine 13, 1-13, 2015 | 20 | 2015 |
Hepatocyte‐specific expression of human carboxylesterase 1 attenuates diet‐induced steatohepatitis and hyperlipidemia in mice Y Xu, Y Zhu, FC Bawa, S Hu, X Pan, L Yin, Y Zhang Hepatology communications 4 (4), 527-539, 2020 | 19 | 2020 |