Structural and immunologic characterization of bovine, horse, and rabbit serum albumins KA Majorek, PJ Porebski, A Dayal, MD Zimmerman, K Jablonska, ... Molecular immunology 52 (3-4), 174-182, 2012 | 1041 | 2012 |
The association between sterilizing activity and drug distribution into tuberculosis lesions B Prideaux, LE Via, MD Zimmerman, S Eum, J Sarathy, P O'brien, C Chen, ... Nature medicine 21 (10), 1223-1227, 2015 | 473 | 2015 |
A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats N Beloglazova, G Brown, MD Zimmerman, M Proudfoot, KS Makarova, ... Journal of Biological Chemistry 283 (29), 20361-20371, 2008 | 268 | 2008 |
Immune activation of the host cell induces drug tolerance in Mycobacterium tuberculosis both in vitro and in vivo Y Liu, S Tan, L Huang, RB Abramovitch, KH Rohde, MD Zimmerman, ... Journal of Experimental Medicine 213 (5), 809-825, 2016 | 188 | 2016 |
Tuberculosis drugs’ distribution and emergence of resistance in patient’s lung lesions: a mechanistic model and tool for regimen and dose optimization N Strydom, SV Gupta, WS Fox, LE Via, H Bang, M Lee, S Eum, TS Shim, ... PLoS medicine 16 (4), e1002773, 2019 | 162 | 2019 |
Bedaquiline and Pyrazinamide Treatment Responses Are Affected by Pulmonary Lesion Heterogeneity in Mycobacterium tuberculosis Infected C3HeB/FeJ Mice SM Irwin, B Prideaux, ER Lyon, MD Zimmerman, EJ Brooks, CA Schrupp, ... ACS infectious diseases 2 (4), 251-267, 2016 | 130 | 2016 |
A naturally inspired antibiotic to target multidrug-resistant pathogens Z Wang, B Koirala, Y Hernandez, M Zimmerman, S Park, DS Perlin, ... Nature 601 (7894), 606-611, 2022 | 129 | 2022 |
Statin adjunctive therapy shortens the duration of TB treatment in mice NK Dutta, N Bruiners, ML Pinn, MD Zimmerman, B Prideaux, V Dartois, ... Journal of Antimicrobial Chemotherapy 71 (6), 1570-1577, 2016 | 110 | 2016 |
The future of crystallography in drug discovery H Zheng, J Hou, MD Zimmerman, A Wlodawer, W Minor Expert opinion on drug discovery 9 (2), 125-137, 2014 | 110 | 2014 |
A public database of macromolecular diffraction experiments M Grabowski, KM Langner, M Cymborowski, PJ Porebski, P Sroka, ... Acta Crystallographica Section D: Structural Biology 72 (11), 1181-1193, 2016 | 109 | 2016 |
X-ray crystallography over the past decade for novel drug discovery–where are we heading next? H Zheng, KB Handing, MD Zimmerman, IG Shabalin, SC Almo, W Minor Expert opinion on drug discovery 10 (9), 975-989, 2015 | 108 | 2015 |
Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development T Beites, K O’Brien, D Tiwari, CA Engelhart, S Walters, J Andrews, ... Nature communications 10 (1), 4970, 2019 | 99 | 2019 |
Structural insight into the mechanism of substrate specificity and catalytic activity of an HD-domain phosphohydrolase: the 5′-deoxyribonucleotidase YfbR from Escherichia coli MD Zimmerman, M Proudfoot, A Yakunin, W Minor Journal of molecular biology 378 (1), 215-226, 2008 | 88 | 2008 |
CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis S Li, NC Poulton, JS Chang, ZA Azadian, MA DeJesus, N Ruecker, ... Nature Microbiology 7 (6), 766-779, 2022 | 85 | 2022 |
The Structural Biology Knowledgebase: a portal to protein structures, sequences, functions, and methods MJ Gabanyi, PD Adams, K Arnold, L Bordoli, LG Carter, ... Journal of structural and functional genomics 12, 45-54, 2011 | 85 | 2011 |
Host-mediated bioactivation of pyrazinamide: implications for efficacy, resistance, and therapeutic alternatives LE Via, R Savic, DM Weiner, MD Zimmerman, B Prideaux, SM Irwin, ... ACS infectious diseases 1 (5), 203-214, 2015 | 84 | 2015 |
Ethambutol partitioning in tuberculous pulmonary lesions explains its clinical efficacy M Zimmerman, J Lestner, B Prideaux, P O'Brien, I Dias-Freedman, ... Antimicrobial agents and chemotherapy 61 (9), 10.1128/aac. 00924-17, 2017 | 79 | 2017 |
Mass spectrometry imaging of levofloxacin distribution in TB-infected pulmonary lesions by MALDI-MSI and continuous liquid microjunction surface sampling B Prideaux, MS ElNaggar, M Zimmerman, JM Wiseman, X Li, V Dartois International journal of mass spectrometry 377, 699-708, 2015 | 75 | 2015 |
Analysis of solvent content and oligomeric states in protein crystals—does symmetry matter? M Chruszcz, W Potrzebowski, MD Zimmerman, M Grabowski, H Zheng, ... Protein Science 17 (4), 623-632, 2008 | 75 | 2008 |
Gut Microbiota Metabolite Indole Propionic Acid Targets Tryptophan Biosynthesis in Mycobacterium tuberculosis DA Negatu, Y Yamada, Y Xi, ML Go, M Zimmerman, U Ganapathy, ... MBio 10 (2), 10.1128/mbio. 02781-18, 2019 | 72 | 2019 |