| Kynurenic acid: the Janus-faced role of an immunomodulatory tryptophan metabolite and its link to pathological conditions E Wirthgen, A Hoeflich, A Rebl, J Günther Frontiers in immunology 8, 1957, 2018 | 327 | 2018 |
| Paternally Inherited IGF2 Mutation and Growth Restriction M Begemann, B Zirn, G Santen, E Wirthgen, L Soellner, HM Büttel, ... New England Journal of Medicine 373 (4), 349-356, 2015 | 237 | 2015 |
| Limitations and off-target effects of tryptophan-related IDO inhibitors in cancer treatment J Günther, J Däbritz, E Wirthgen Frontiers in immunology 10, 1801, 2019 | 117 | 2019 |
| Effects of Feeding Milk Replacer Ad Libitum or in Restricted Amounts for the First Five Weeks of Life on the Growth, Metabolic Adaptation, and Immune Status of … CT Schäff, J Gruse, J Maciej, M Mielenz, E Wirthgen, A Hoeflich, ... PLoS One 11 (12), e0168974, 2016 | 102 | 2016 |
| Cytokines in milk and the role of TGF-beta J Brenmoehl, D Ohde, E Wirthgen, A Hoeflich Best Practice & Research Clinical Endocrinology & Metabolism 32 (1), 47-56, 2018 | 67 | 2018 |
| Endotoxin‐induced tryptophan degradation along the kynurenine pathway: the role of indolamine 2, 3‐dioxygenase and aryl hydrocarbon receptor‐mediated immunosuppressive effects … E Wirthgen, A Hoeflich Journal of Amino Acids 2015 (1), 973548, 2015 | 65 | 2015 |
| Activation of indoleamine 2, 3-dioxygenase by LPS in a porcine model E Wirthgen, M Tuchscherer, W Otten, G Domanska, K Wollenhaupt, ... Innate immunity 20 (1), 30-39, 2014 | 56 | 2014 |
| The role of epigenetic modifications for the pathogenesis of Crohn's disease M Hornschuh, E Wirthgen, M Wolfien, KP Singh, O Wolkenhauer, ... Clinical epigenetics 13 (1), 108, 2021 | 43 | 2021 |
| Polyethylene glycol-coupled IGF1 delays motor function defects in a mouse model of spinal muscular atrophy with respiratory distress type 1 F Krieger, N Elflein, S Saenger, E Wirthgen, K Rak, S Frantz, A Hoeflich, ... Brain 137 (5), 1374-1393, 2014 | 42 | 2014 |
| Methylating micronutrient supplementation during pregnancy influences foetal hepatic gene expression and IGF signalling and increases foetal weight M Oster, W Nuchchanart, N Trakooljul, E Murani, A Zeyner, E Wirthgen, ... European journal of nutrition 55, 1717-1727, 2016 | 38 | 2016 |
| Activation of the kynurenine pathway in human malignancies can be suppressed by the cyclin-dependent kinase inhibitor dinaciclib C Riess, B Schneider, H Kehnscherper, J Gesche, N Irmscher, F Shokraie, ... Frontiers in immunology 11, 55, 2020 | 33 | 2020 |
| Quantitative Western ligand blotting reveals common patterns and differential features of IGFBP-fingerprints in domestic ruminant breeds and species E Wirthgen, C Höflich, M Spitschak, C Helmer, B Brand, J Langbein, ... Growth Hormone & IGF Research 26, 42-49, 2016 | 26 | 2016 |
| Immunomodulatory roles of tryptophan metabolites in inflammation and cancer J Günther, F Fallarino, D Fuchs, E Wirthgen Frontiers in Immunology 11, 1497, 2020 | 24 | 2020 |
| The immunomodulator 1-methyltryptophan drives tryptophan catabolism toward the kynurenic acid branch E Wirthgen, AK Leonard, C Scharf, G Domanska Frontiers in immunology 11, 313, 2020 | 24 | 2020 |
| Analysis of the IGF-system in milk from farm animals–Occurrence, regulation, and biomarker potential Z Meyer, C Höflich, E Wirthgen, S Olm, HM Hammon, A Hoeflich Growth Hormone & IGF Research 35, 1-7, 2017 | 24 | 2017 |
| Validation of serum IGF-I as a biomarker to monitor the bioactivity of exogenous growth hormone agonists and antagonists in rabbits M Bielohuby, SH Zarkesh-Esfahani, J Manolopoulou, E Wirthgen, ... Disease models & mechanisms 7 (11), 1263-1273, 2014 | 24 | 2014 |
| Effects of parturition and feed restriction on concentrations and distribution of the insulin-like growth factor-binding proteins in plasma and cerebrospinal fluid of dairy cows T Laeger, E Wirthgen, M Piechotta, F Metzger, CC Metges, B Kuhla, ... Journal of Dairy Science 97 (5), 2876-2885, 2014 | 23 | 2014 |
| Characterization of igf1 and igf2 genes during maraena whitefish (Coregonus maraena) ontogeny and the effect of temperature on embryogenesis and igf expression M Nipkow, E Wirthgen, P Luft, A Rebl, A Hoeflich, T Goldammer Growth Hormone & IGF Research 40, 32-43, 2018 | 22 | 2018 |
| Interference of stress with the somatotropic axis in pigs–lights on new biomarkers E Wirthgen, M Kunze, S Goumon, C Walz, C Höflich, M Spitschak, ... Scientific reports 7 (1), 12055, 2017 | 20 | 2017 |
| Control of IGFBP-2 expression by steroids and peptide hormones in vertebrates A Hoeflich, E Wirthgen, R David, CF Classen, M Spitschak, J Brenmoehl Frontiers in Endocrinology 5, 43, 2014 | 20 | 2014 |
