Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ RT Nolte, GB Wisely, S Westin, JE Cobb, MH Lambert, R Kurokawa, ... Nature 395 (6698), 137-143, 1998 | 2453 | 1998 |
Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α ML Moss, SLC Jin, ME Milla, W Burkhart, HL Carter, WJ Chen, WC Clay, ... Nature 385 (6618), 733-736, 1997 | 2134 | 1997 |
A critical assessment of docking programs and scoring functions GL Warren, CW Andrews, AM Capelli, B Clarke, J LaLonde, MH Lambert, ... Journal of medicinal chemistry 49 (20), 5912-5931, 2006 | 1961 | 2006 |
Molecular recognition of fatty acids by peroxisome proliferator–activated receptors HE Xu, MH Lambert, VG Montana, DJ Parks, SG Blanchard, PJ Brown, ... Molecular cell 3 (3), 397-403, 1999 | 1511 | 1999 |
A selective peroxisome proliferator-activated receptor δ agonist promotes reverse cholesterol transport WR Oliver Jr, JL Shenk, MR Snaith, CS Russell, KD Plunket, NL Bodkin, ... Proceedings of the national academy of sciences 98 (9), 5306-5311, 2001 | 1467 | 2001 |
Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition RK Bledsoe, VG Montana, TB Stanley, CJ Delves, CJ Apolito, DD McKee, ... Cell 110 (1), 93-105, 2002 | 1000 | 2002 |
The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity RE Watkins, GB Wisely, LB Moore, JL Collins, MH Lambert, SP Williams, ... Science 292 (5525), 2329-2333, 2001 | 954 | 2001 |
The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution SA Jones, LB Moore, JL Shenk, GB Wisely, GA Hamilton, DD McKee, ... Molecular endocrinology 14 (1), 27-39, 2000 | 876 | 2000 |
Peroxisome proliferator–activated receptor γ and metabolic disease TM Willson, MH Lambert, SA Kliewer Annual review of biochemistry 70 (1), 341-367, 2001 | 792 | 2001 |
Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARα HE Xu, TB Stanley, VG Montana, MH Lambert, BG Shearer, JE Cobb, ... Nature 415 (6873), 813-817, 2002 | 764 | 2002 |
Asymmetry in the PPARγ/RXRα crystal structure reveals the molecular basis of heterodimerization among nuclear receptors RT Gampe, VG Montana, MH Lambert, AB Miller, RK Bledsoe, MV Milburn, ... Molecular cell 5 (3), 545-555, 2000 | 743 | 2000 |
Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors HE Xu, MH Lambert, VG Montana, KD Plunket, LB Moore, JL Collins, ... Proceedings of the National Academy of Sciences 98 (24), 13919-13924, 2001 | 677 | 2001 |
Molecular determinants of nuclear receptor–corepressor interaction V Perissi, LM Staszewski, EM McInerney, R Kurokawa, A Krones, ... Genes & development 13 (24), 3198-3208, 1999 | 625 | 1999 |
Peroxisome proliferator-activated receptors: from genes to physiology. SA Kliewer, HE Xu, MH Lambert, TM Willson Recent progress in hormone research 56, 239-263, 2001 | 562 | 2001 |
Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes JM Maglich, DJ Parks, LB Moore, JL Collins, B Goodwin, AN Billin, ... Journal of Biological Chemistry 278 (19), 17277-17283, 2003 | 532 | 2003 |
Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors LB Moore, JM Maglich, DD McKee, B Wisely, TM Willson, SA Kliewer, ... Molecular endocrinology 16 (5), 977-986, 2002 | 454 | 2002 |
Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity RX Xu, AM Hassell, D Vanderwall, MH Lambert, WD Holmes, MA Luther, ... Science 288 (5472), 1822-1825, 2000 | 441 | 2000 |
2.1 Å Crystal Structure of Human PXR in Complex with the St. John's Wort Compound Hyperforin, RE Watkins, JM Maglich, LB Moore, GB Wisely, SM Noble, ... Biochemistry 42 (6), 1430-1438, 2003 | 431 | 2003 |
Structure of the catalytic domain of fibroblast collagenase complexed with an inhibitor B Lovejoy, A Cleasby, AM Hassell, K Longley, MA Luther, D Weigl, ... Science 263 (5145), 375-377, 1994 | 421 | 1994 |
Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell … A Ludwig, C Hundhausen, MH Lambert, N Broadway, RC Andrews, ... Combinatorial chemistry & high throughput screening 8 (2), 161-171, 2005 | 418 | 2005 |