Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis SP Thayer, MP di Magliano, PW Heiser, CM Nielsen, DJ Roberts, ... Nature 425 (6960), 851-856, 2003 | 1955 | 2003 |
Hedgehog signalling in cancer formation and maintenance MP di Magliano, M Hebrok Nature reviews cancer 3 (12), 903-911, 2003 | 1078 | 2003 |
Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice MA Collins, F Bednar, Y Zhang, JC Brisset, S Galbán, CJ Galbán, ... The Journal of clinical investigation 122 (2), 639-653, 2012 | 838 | 2012 |
Roles for KRAS in pancreatic tumor development and progression MP Di Magliano, CD Logsdon Gastroenterology 144 (6), 1220-1229, 2013 | 488 | 2013 |
c-Met is a marker of pancreatic cancer stem cells and therapeutic target C Li, JJ Wu, M Hynes, J Dosch, B Sarkar, TH Welling, MP di Magliano, ... Gastroenterology 141 (6), 2218-2227. e5, 2011 | 426 | 2011 |
Hedgehog/Ras interactions regulate early stages of pancreatic cancer MP Di Magliano, S Sekine, A Ermilov, J Ferris, AA Dlugosz, M Hebrok Genes & development 20 (22), 3161-3173, 2006 | 354 | 2006 |
Macrophage-released pyrimidines inhibit gemcitabine therapy in pancreatic cancer CJ Halbrook, C Pontious, I Kovalenko, L Lapienyte, S Dreyer, HJ Lee, ... Cell metabolism 29 (6), 1390-1399. e6, 2019 | 348 | 2019 |
Myeloid cells are required for PD-1/PD-L1 checkpoint activation and the establishment of an immunosuppressive environment in pancreatic cancer Y Zhang, A Velez-Delgado, E Mathew, D Li, FM Mendez, K Flannagan, ... Gut 66 (1), 124-136, 2017 | 332 | 2017 |
Pax8 has a key role in thyroid cell differentiation M Pasca di Magliano, R Di Lauro, M Zannini Proceedings of the National Academy of Sciences 97 (24), 13144-13149, 2000 | 311 | 2000 |
Pancreatic cancer: Advances and challenges CJ Halbrook, CA Lyssiotis, MP di Magliano, A Maitra Cell 186 (8), 1729-1754, 2023 | 306 | 2023 |
Regulatory T-cell depletion alters the tumor microenvironment and accelerates pancreatic carcinogenesis Y Zhang, J Lazarus, NG Steele, W Yan, HJ Lee, ZC Nwosu, CJ Halbrook, ... Cancer discovery 10 (3), 422-439, 2020 | 298 | 2020 |
Common activation of canonical Wnt signaling in pancreatic adenocarcinoma M Pasca di Magliano, AV Biankin, PW Heiser, DA Cano, PJA Gutierrez, ... PloS one 2 (11), e1155, 2007 | 280 | 2007 |
Multimodal mapping of the tumor and peripheral blood immune landscape in human pancreatic cancer NG Steele, ES Carpenter, SB Kemp, VR Sirihorachai, S The, L Delrosario, ... Nature Cancer 1 (11), 1097-1112, 2020 | 274 | 2020 |
Interleukin-6 is required for pancreatic cancer progression by promoting MAPK signaling activation and oxidative stress resistance Y Zhang, W Yan, MA Collins, F Bednar, S Rakshit, BR Zetter, BZ Stanger, ... Cancer research 73 (20), 6359-6374, 2013 | 266 | 2013 |
Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis T Decker, MP di Magliano, S McManus, Q Sun, C Bonifer, H Tagoh, ... Immunity 30 (4), 508-520, 2009 | 231 | 2009 |
Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity C Hutton, F Heider, A Blanco-Gomez, A Banyard, A Kononov, X Zhang, ... Cancer cell 39 (9), 1227-1244. e20, 2021 | 212 | 2021 |
Canonical wnt signaling is required for pancreatic carcinogenesis Y Zhang, JP Morris IV, W Yan, HK Schofield, A Gurney, DM Simeone, ... Cancer research 73 (15), 4909-4922, 2013 | 207 | 2013 |
Metastatic pancreatic cancer is dependent on oncogenic Kras in mice MA Collins, JC Brisset, Y Zhang, F Bednar, J Pierre, KA Heist, CJ Galbán, ... PloS one 7 (12), e49707, 2012 | 206 | 2012 |
Inhibition of hedgehog signaling alters fibroblast composition in pancreatic cancer NG Steele, G Biffi, SB Kemp, Y Zhang, D Drouillard, LJ Syu, Y Hao, ... Clinical Cancer Research 27 (7), 2023-2037, 2021 | 195 | 2021 |
Inhibition of ATM increases interferon signaling and sensitizes pancreatic cancer to immune checkpoint blockade therapy Q Zhang, MD Green, X Lang, J Lazarus, JD Parsels, S Wei, LA Parsels, ... Cancer research 79 (15), 3940-3951, 2019 | 183 | 2019 |