| Oct4-induced pluripotency in adult neural stem cells JB Kim, V Sebastiano, G Wu, MJ Araúzo-Bravo, P Sasse, L Gentile, K Ko, ... cell 136 (3), 411-419, 2009 | 1308 | 2009 |
| DNA sequencing of maternal plasma to detect Down syndrome: an international clinical validation study GE Palomaki, EM Kloza, GM Lambert-Messerlian, JE Haddow, ... Genetics in medicine 13 (11), 913-920, 2011 | 1228 | 2011 |
| Quantitative high-throughput analysis of DNA methylation patterns by base-specific cleavage and mass spectrometry M Ehrich, MR Nelson, P Stanssens, M Zabeau, T Liloglou, G Xinarianos, ... Proceedings of the National Academy of Sciences 102 (44), 15785-15790, 2005 | 971 | 2005 |
| DNA sequencing of maternal plasma reliably identifies trisomy 18 and trisomy 13 as well as Down syndrome: an international collaborative study GE Palomaki, C Deciu, EM Kloza, GM Lambert-Messerlian, JE Haddow, ... Genetics in medicine 14 (3), 296-305, 2012 | 769 | 2012 |
| Noninvasive detection of fetal trisomy 21 by sequencing of DNA in maternal blood: a study in a clinical setting M Ehrich, C Deciu, T Zwiefelhofer, JA Tynan, L Cagasan, R Tim, V Lu, ... American journal of obstetrics and gynecology 204 (3), 205. e1-205. e11, 2011 | 759 | 2011 |
| Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice M Kansara, M Tsang, L Kodjabachian, NA Sims, MK Trivett, M Ehrich, ... The Journal of clinical investigation 119 (4), 837-851, 2009 | 336 | 2009 |
| Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing HG Linhart, H Lin, Y Yamada, E Moran, EJ Steine, S Gokhale, G Lo, ... Genes & development 21 (23), 3110-3122, 2007 | 317 | 2007 |
| Noninvasive prenatal detection of sex chromosomal aneuploidies by sequencing circulating cell‐free DNA from maternal plasma AR Mazloom, Ž Džakula, P Oeth, H Wang, T Jensen, J Tynan, ... Prenatal diagnosis 33 (6), 591-597, 2013 | 233 | 2013 |
| DNA sequencing of maternal plasma to identify Down syndrome and other trisomies in multiple gestations JA Canick, EM Kloza, GM Lambert‐Messerlian, JE Haddow, M Ehrich, ... Prenatal diagnosis 32 (8), 730-734, 2012 | 227 | 2012 |
| Determination of fetal DNA fraction from the plasma of pregnant women using sequence read counts SK Kim, G Hannum, J Geis, J Tynan, G Hogg, C Zhao, TJ Jensen, ... Prenatal diagnosis 35 (8), 810-815, 2015 | 219 | 2015 |
| Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses M Ehrich, AOH Nygren, TJ Jensen | 212* | 2011 |
| Quantification of fetal DNA by use of methylation-based DNA discrimination AOH Nygren, J Dean, TJ Jensen, S Kruse, W Kwong, D van den Boom, ... Clinical Chemistry 56 (10), 1627-1635, 2010 | 198 | 2010 |
| Noninvasive prenatal screening for fetal trisomies 21, 18, 13 and the common sex chromosome aneuploidies from maternal blood using massively parallel genomic sequencing of DNA RP Porreco, TJ Garite, K Maurel, B Marusiak, OCR Network, M Ehrich, ... American Journal of Obstetrics and Gynecology 211 (4), 365. e1-365. e12, 2014 | 195 | 2014 |
| Clinical validation of a noninvasive prenatal test for genomewide detection of fetal copy number variants RB Lefkowitz, JA Tynan, T Liu, Y Wu, AR Mazloom, E Almasri, G Hogg, ... American journal of obstetrics and gynecology 215 (2), 227. e1-227. e16, 2016 | 194 | 2016 |
| Quantitative DNA methylation predicts survival in adult acute myeloid leukemia L Bullinger, M Ehrich, K Döhner, RF Schlenk, H Döhner, MR Nelson, ... Blood, The Journal of the American Society of Hematology 115 (3), 636-642, 2010 | 189 | 2010 |
| Methods and processes for non-invasive assessment of genetic variations C Deciu, Z Dzakula, M Ehrich, SK Kim US Patent 9,367,663, 2016 | 182 | 2016 |
| Detection of fetal subchromosomal abnormalities by sequencing circulating cell-free DNA from maternal plasma C Zhao, J Tynan, M Ehrich, G Hannum, R McCullough, JS Saldivar, ... Clinical chemistry 61 (4), 608-616, 2015 | 179 | 2015 |
| Cytosine methylation profiling of cancer cell lines M Ehrich, J Turner, P Gibbs, L Lipton, M Giovanneti, C Cantor, ... Proceedings of the National Academy of Sciences 105 (12), 4844-4849, 2008 | 174 | 2008 |
| Processes and kits for identifying aneuploidy M Ehrich, G Del Mistro, C Deciu, YQ Chen, RM McCullough, RC Tim US Patent 9,926,593, 2018 | 169 | 2018 |
| Hypermethylation of genes for diagnosis and risk stratification of prostate cancer DK Vanaja, M Ehrich, D Van den Boom, JC Cheville, RJ Karnes, ... Cancer investigation 27 (5), 549-560, 2009 | 168 | 2009 |
