Trends in peptide drug discovery M Muttenthaler, GF King, DJ Adams, PF Alewood Nature reviews Drug discovery 20 (4), 309-325, 2021 | 1084 | 2021 |
Discovery, synthesis, and structure–activity relationships of conotoxins KB Akondi, M Muttenthaler, S Dutertre, Q Kaas, DJ Craik, RJ Lewis, ... Chemical Reviews 114 (11), 5815-5847, 2014 | 302 | 2014 |
Conotoxins: chemistry and biology AH Jin, M Muttenthaler, S Dutertre, SWA Himaya, Q Kaas, DJ Craik, ... Chemical reviews 119 (21), 11510-11549, 2019 | 199 | 2019 |
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design J Koehbach, M O’Brien, M Muttenthaler, M Miazzo, M Akcan, AG Elliott, ... Proceedings of the National Academy of Sciences 110 (52), 21183-21188, 2013 | 159 | 2013 |
Selenopeptide chemistry M Muttenthaler, PF Alewood Journal of peptide science: an official publication of the European Peptide …, 2008 | 159 | 2008 |
Solving the α-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists M Muttenthaler, ST Nevin, AA Grishin, ST Ngo, PT Choy, NL Daly, SH Hu, ... Journal of the American Chemical Society 132 (10), 3514-3522, 2010 | 134 | 2010 |
Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain AD De Araujo, M Mobli, J Castro, AM Harrington, I Vetter, Z Dekan, ... Nature communications 5 (1), 3165, 2014 | 133 | 2014 |
Modulating oxytocin activity and plasma stability by disulfide bond engineering M Muttenthaler, A Andersson, AD de Araujo, Z Dekan, RJ Lewis, ... Journal of medicinal chemistry 53 (24), 8585-8596, 2010 | 133 | 2010 |
Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors C W Gruber, M Muttenthaler, M Freissmuth Current pharmaceutical design 16 (28), 3071-3088, 2010 | 119 | 2010 |
Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptides S Dutertre, D Croker, NL Daly, A Andersson, M Muttenthaler, ... Journal of Biological Chemistry 283 (11), 7100-7108, 2008 | 97 | 2008 |
α-Conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of α3β4 nicotinic acetylcholine receptors AA Grishin, CIA Wang, M Muttenthaler, PF Alewood, RJ Lewis, DJ Adams Journal of Biological Chemistry 285 (29), 22254-22263, 2010 | 86 | 2010 |
Mucosal biofilms are an endoscopic feature of irritable bowel syndrome and ulcerative colitis M Baumgartner, M Lang, H Holley, D Crepaz, B Hausmann, P Pjevac, ... Gastroenterology 161 (4), 1245-1256. e20, 2021 | 85 | 2021 |
Discovery of defense-and neuropeptides in social ants by genome-mining CW Gruber, M Muttenthaler PLoS One 7 (3), e32559, 2012 | 77 | 2012 |
Insights into the molecular evolution of oxytocin receptor ligand binding J Koehbach, T Stockner, C Bergmayr, M Muttenthaler, CW Gruber Biochemical Society Transactions 41 (1), 197-204, 2013 | 72 | 2013 |
Design and characterization of superpotent bivalent ligands targeting oxytocin receptor dimers via a channel-like structure M Busnelli, G Kleinau, M Muttenthaler, S Stoev, M Manning, L Bibic, ... Journal of medicinal chemistry 59 (15), 7152-7166, 2016 | 68 | 2016 |
Structure-activity studies on alpha-conotoxins M Muttenthaler, K B Akondi, P F Alewood Current pharmaceutical design 17 (38), 4226-4241, 2011 | 68 | 2011 |
Lipid Bilayer Crossing The Gate of Symmetry. Water-Soluble Phenylproline-Based Blood-Brain Barrier Shuttles P Arranz-Gibert, B Guixer, M Malakoutikhah, M Muttenthaler, F Guzmán, ... Journal of the American Chemical Society 137 (23), 7357-7364, 2015 | 61 | 2015 |
Methods, setup and safe handling for anhydrous hydrogen fluoride cleavage in Boc solid-phase peptide synthesis M Muttenthaler, F Albericio, PE Dawson Nature Protocols 10 (7), 1067-1083, 2015 | 60 | 2015 |
Trefoil factor family: Unresolved questions and clinical perspectives NB Emidio, W Hoffmann, SM Brierley, M Muttenthaler Trends in biochemical sciences 44 (5), 387-390, 2019 | 57 | 2019 |
Exploring bioactive peptides from natural sources for oxytocin and vasopressin drug discovery CW Gruber, J Koehbach, M Muttenthaler Future medicinal chemistry 4 (14), 1791-1798, 2012 | 53 | 2012 |