Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors J Osipiuk, SA Azizi, S Dvorkin, M Endres, R Jedrzejczak, KA Jones, ... Nature communications 12 (1), 743, 2021 | 436 | 2021 |
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 N Drayman, JK DeMarco, KA Jones, SA Azizi, HM Froggatt, K Tan, ... Science 373 (6557), 931-936, 2021 | 219 | 2021 |
Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses LC Nguyen, D Yang, V Nicolaescu, TJ Best, H Gula, D Saxena, ... Science Advances 8 (8), eabi6110, 2022 | 126 | 2022 |
Orthogonal luciferase–luciferin pairs for bioluminescence imaging KA Jones, WB Porterfield, CM Rathbun, DC McCutcheon, MA Paley, ... Journal of the American Chemical Society 139 (6), 2351-2358, 2017 | 108 | 2017 |
Site-selective C–H halogenation using flavin-dependent halogenases identified via family-wide activity profiling BF Fisher, HM Snodgrass, KA Jones, MC Andorfer, JC Lewis ACS central science 5 (11), 1844-1856, 2019 | 104 | 2019 |
A “caged” luciferin for imaging cell–cell contacts WB Porterfield, KA Jones, DC McCutcheon, JA Prescher Journal of the American Chemical Society 137 (27), 8656-8659, 2015 | 87 | 2015 |
Improved cyclopropene reporters for probing protein glycosylation DM Patterson, KA Jones, JA Prescher Molecular BioSystems 10 (7), 1693-1697, 2014 | 82 | 2014 |
Cannabidiol inhibits SARS-CoV-2 replication and promotes the host innate immune response LC Nguyen, D Yang, V Nicolaescu, TJ Best, T Ohtsuki, SN Chen, ... biorxiv, 2021 | 59 | 2021 |
Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro N Drayman, KA Jones, SA Azizi, HM Froggatt, K Tan, NI Maltseva, S Chen, ... BioRxiv, 2020.08. 31.274639, 2020 | 45 | 2020 |
Parallel screening for rapid identification of orthogonal bioluminescent tools CM Rathbun, WB Porterfield, KA Jones, MJ Sagoe, MR Reyes, CT Hua, ... ACS central science 3 (12), 1254-1261, 2017 | 45 | 2017 |
Brominated luciferins are versatile bioluminescent probes RC Steinhardt, CM Rathbun, BT Krull, JM Yu, Y Yang, BD Nguyen, ... ChemBioChem 18 (1), 96-100, 2017 | 44 | 2017 |
Vitamin D metabolites inhibit hepatitis C virus and modulate cellular gene expression JA Gutierrez, KA Jones, R Flores, A Singhania, CH Woelk, RT Schooley, ... Journal of virology & antiviral research 3 (3), 2014 | 40 | 2014 |
Small molecule-inducible RNA-targeting systems for temporal control of RNA regulation S Rauch, KA Jones, BC Dickinson ACS central science 6 (11), 1987-1996, 2020 | 38 | 2020 |
Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays Y Gupta, D Maciorowski, SE Zak, KA Jones, RS Kathayat, SA Azizi, ... Methods 195, 57-71, 2021 | 37 | 2021 |
Development of a split esterase for protein–protein interaction-dependent small-molecule activation KA Jones, K Kentala, MW Beck, W An, AR Lippert, JC Lewis, ... ACS central science 5 (11), 1768-1776, 2019 | 32 | 2019 |
Pyridone luciferins and mutant luciferases for bioluminescence imaging BS Zhang, KA Jones, DC McCutcheon, JA Prescher ChemBioChem 19 (5), 470-477, 2018 | 28 | 2018 |
The impact of an electronic medical record nudge on reducing testing for hospital-onset Clostridioides difficile infection JR Howard-Anderson, ME Sexton, C Robichaux, Z Wiley, JB Varkey, ... Infection Control & Hospital Epidemiology 41 (4), 411-417, 2020 | 27 | 2020 |
Defective inhibition of B-cell proliferation by Wiskott-Aldrich syndrome protein-deficient regulatory T cells M Adriani, KA Jones, T Uchiyama, MR Kirby, C Silvin, SM Anderson, ... Blood, The Journal of the American Society of Hematology 117 (24), 6608-6611, 2011 | 27 | 2011 |
Antiviral evaluation of hydroxyethylamine analogs: Inhibitors of SARS-CoV-2 main protease (3CLpro), a virtual screening and simulation approach Y Gupta, S Kumar, SE Zak, KA Jones, C Upadhyay, N Sharma, SA Azizi, ... Bioorganic & Medicinal Chemistry 47, 116393, 2021 | 20 | 2021 |
Phage-assisted continuous evolution and selection of enzymes for chemical synthesis KA Jones, HM Snodgrass, K Belsare, BC Dickinson, JC Lewis ACS Central Science 7 (9), 1581-1590, 2021 | 20 | 2021 |