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Basil Hubbard
Basil Hubbard
Associate Professor, University of Toronto
在 utoronto.ca 的电子邮件经过验证
标题
引用次数
引用次数
年份
SIRT1 is required for AMPK activation and the beneficial effects of resveratrol on mitochondrial function
NL Price, AP Gomes, AJY Ling, FV Duarte, A Martin-Montalvo, BJ North, ...
Cell metabolism 15 (5), 675-690, 2012
16422012
Declining NAD+ induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging
AP Gomes, NL Price, AJY Ling, JJ Moslehi, MK Montgomery, L Rajman, ...
Cell 155 (7), 1624-1638, 2013
14522013
Kinase-targeted cancer therapies: progress, challenges and future directions
KS Bhullar, NO Lagarón, EM McGowan, I Parmar, A Jha, BP Hubbard, ...
Molecular cancer 17, 1-20, 2018
11342018
Evidence for a common mechanism of SIRT1 regulation by allosteric activators
BP Hubbard, AP Gomes, H Dai, J Li, AW Case, T Considine, TV Riera, ...
Science 339 (6124), 1216-1219, 2013
6532013
Small molecule SIRT1 activators for the treatment of aging and age-related diseases
BP Hubbard, DA Sinclair
Trends in pharmacological sciences 35 (3), 146-154, 2014
6342014
SRT1720 improves survival and healthspan of obese mice
RK Minor, JA Baur, AP Gomes, TM Ward, A Csiszar, EM Mercken, ...
Scientific reports 1 (1), 1-11, 2011
3342011
Lifespan and healthspan extension by resveratrol
KS Bhullar, BP Hubbard
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (6 …, 2015
3122015
SIRT1 Activation by Small Molecules: KINETIC AND BIOPHYSICAL EVIDENCE FOR DIRECT INTERACTION OF ENZYME AND ACTIVATOR♦
H Dai, L Kustigian, D Carney, A Case, T Considine, BP Hubbard, ...
Journal of Biological Chemistry 285 (43), 32695-32703, 2010
2592010
A conserved NAD+ binding pocket that regulates protein-protein interactions during aging
J Li, MS Bonkowski, S Moniot, D Zhang, BP Hubbard, AJY Ling, ...
Science 355 (6331), 1312-1317, 2017
2092017
Structural study of Maya Blue: textural, thermal and solid-state multinuclear magnetic resonance characterization of the palygorskite-indigo and sepiolite-indigo adducts
B Hubbard, W Kuang, A Moser, GA Facey, C Detellier
Clays and clay minerals 51 (3), 318-326, 2003
1722003
Berberine protects against high fat diet-induced dysfunction in muscle mitochondria by inducing SIRT1-dependent mitochondrial biogenesis
AP Gomes, FV Duarte, P Nunes, BP Hubbard, JS Teodoro, AT Varela, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (2), 185-195, 2012
1652012
Incorporation of bridged nucleic acids into CRISPR RNAs improves Cas9 endonuclease specificity
CR Cromwell, K Sung, J Park, AR Krysler, J Jovel, SK Kim, BP Hubbard
Nature communications 9 (1), 1448, 2018
1642018
Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein
M Bernier, RK Paul, A Martin-Montalvo, M Scheibye-Knudsen, S Song, ...
Journal of Biological Chemistry 286 (22), 19270-19279, 2011
1512011
Continuous directed evolution of DNA-binding proteins to improve TALEN specificity
BP Hubbard, AH Badran, JA Zuris, JP Guilinger, KM Davis, L Chen, ...
Nature methods 12 (10), 939-942, 2015
1442015
The lifespan extension effects of resveratrol are conserved in the honey bee and may be driven by a mechanism related to caloric restriction
B Rascón, BP Hubbard, DA Sinclair, GV Amdam
Aging (Albany NY) 4 (7), 499, 2012
1382012
JNK phosphorylates SIRT6 to stimulate DNA double-strand break repair in response to oxidative stress by recruiting PARP1 to DNA breaks
M Van Meter, M Simon, G Tombline, A May, TD Morello, BP Hubbard, ...
Cell reports 16 (10), 2641-2650, 2016
1342016
Identification of a SIRT1 mutation in a family with type 1 diabetes
A Biason-Lauber, M Böni-Schnetzler, BP Hubbard, K Bouzakri, A Brunner, ...
Cell metabolism 17 (3), 448-455, 2013
1342013
Characterization of murine SIRT3 transcript variants and corresponding protein products
Y Yang, BP Hubbard, DA Sinclair, Q Tong
Journal of cellular biochemistry 111 (4), 1051-1058, 2010
512010
Evolution of TALENs
DR Liu, B Hubbard, AH Badran
US Patent 10,612,011, 2020
362020
Tripeptide IRW initiates differentiation in osteoblasts via the RUNX2 pathway
N Shang, KS Bhullar, BP Hubbard, J Wu
Biochimica et Biophysica Acta (BBA)-General Subjects 1863 (6), 1138-1146, 2019
352019
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