| Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy DH Kim, MA Behlke, SD Rose, MS Chang, S Choi, JJ Rossi Nature biotechnology 23 (2), 222-226, 2005 | 1258 | 2005 |
| Identification of preexisting adaptive immunity to Cas9 proteins in humans CT Charlesworth, PS Deshpande, DP Dever, J Camarena, VT Lemgart, ... Nature medicine 25 (2), 249-254, 2019 | 948 | 2019 |
| A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells CA Vakulskas, DP Dever, GR Rettig, R Turk, AM Jacobi, MA Collingwood, ... Nature medicine 24 (8), 1216-1224, 2018 | 742 | 2018 |
| Progress towards in vivo use of siRNAs MA Behlke Molecular Therapy 13 (4), 644-670, 2006 | 737 | 2006 |
| Chemical Modification of siRNAs for In Vivo Use MA Behlke Oligonucleotides 18 (4), 305-320, 2008 | 619 | 2008 |
| Functional polarity is introduced by Dicer processing of short substrate RNAs SD Rose, DH Kim, M Amarzguioui, JD Heidel, MA Collingwood, ME Davis, ... Nucleic acids research 33 (13), 4140-4156, 2005 | 533 | 2005 |
| Chemical modification and design of anti-miRNA oligonucleotides KA Lennox, MA Behlke Gene therapy 18 (12), 1111-1120, 2011 | 520 | 2011 |
| A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells JT Marques, T Devosse, D Wang, M Zamanian-Daryoush, P Serbinowski, ... Nature biotechnology 24 (5), 559-565, 2006 | 516 | 2006 |
| Analysis of microRNA turnover in mammalian cells following Dicer1 ablation MP Gantier, CE McCoy, I Rusinova, D Saulep, D Wang, D Xu, AT Irving, ... Nucleic acids research 39 (13), 5692-5703, 2011 | 502 | 2011 |
| Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins RM Quadros, H Miura, DW Harms, H Akatsuka, T Sato, T Aida, R Redder, ... Genome biology 18, 1-15, 2017 | 451 | 2017 |
| Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides KA Lennox, MA Behlke Nucleic acids research 44 (2), 863-877, 2016 | 439 | 2016 |
| Effects of sodium ions on DNA duplex oligomers: improved predictions of melting temperatures R Owczarzy, Y You, BG Moreira, JA Manthey, L Huang, MA Behlke, ... Biochemistry 43 (12), 3537-3554, 2004 | 430 | 2004 |
| Murine T-cell receptor mutants with deletions of beta-chain variable region genes. MA Behlke, HS Chou, K Huppi, DY Loh Proceedings of the National Academy of Sciences 83 (3), 767-771, 1986 | 421 | 1986 |
| Predicting stability of DNA duplexes in solutions containing magnesium and monovalent cations R Owczarzy, BG Moreira, Y You, MA Behlke, JA Walder Biochemistry 47 (19), 5336-5353, 2008 | 416 | 2008 |
| Design of LNA probes that improve mismatch discrimination Y You, BG Moreira, MA Behlke, R Owczarzy Nucleic acids research 34 (8), e60-e60, 2006 | 384 | 2006 |
| Hybridization kinetics and thermodynamics of molecular beacons A Tsourkas, MA Behlke, SD Rose, G Bao Nucleic acids research 31 (4), 1319-1330, 2003 | 379 | 2003 |
| CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy D Rosenblum, A Gutkin, R Kedmi, S Ramishetti, N Veiga, AM Jacobi, ... Science advances 6 (47), eabc9450, 2020 | 357 | 2020 |
| miRNAs control insulin content in pancreatic β‐cells via downregulation of transcriptional repressors T Melkman‐Zehavi, R Oren, S Kredo‐Russo, T Shapira, AD Mandelbaum, ... The EMBO journal 30 (5), 835-845, 2011 | 345 | 2011 |
| Chitosan/siRNA nanoparticle–mediated TNF-α knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model KA Howard, SR Paludan, MA Behlke, F Besenbacher, B Deleuran, ... Molecular therapy 17 (1), 162-168, 2009 | 343 | 2009 |
| Progress toward in vivo use of siRNAs-II GR Rettig, MA Behlke Molecular therapy 20 (3), 483-512, 2012 | 276 | 2012 |
