| LUMPY: a probabilistic framework for structural variant discovery RM Layer, C Chiang, AR Quinlan, IM Hall Genome biology 15, 1-19, 2014 | 1417 | 2014 |
| SpeedSeq: ultra-fast personal genome analysis and interpretation C Chiang, RM Layer, GG Faust, MR Lindberg, DB Rose, EP Garrison, ... Nature methods 12 (10), 966-968, 2015 | 541 | 2015 |
| Extrachromosomal microDNAs and chromosomal microdeletions in normal tissues Y Shibata, P Kumar, R Layer, S Willcox, JR Gagan, JD Griffith, A Dutta Science 336 (6077), 82-86, 2012 | 281 | 2012 |
| An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder DM Werling, H Brand, JY An, MR Stone, L Zhu, JT Glessner, RL Collins, ... Nature genetics 50 (5), 727-736, 2018 | 268 | 2018 |
| A map of constrained coding regions in the human genome JM Havrilla, BS Pedersen, RM Layer, AR Quinlan Nature genetics 51 (1), 88-95, 2019 | 245 | 2019 |
| Mapping and characterization of structural variation in 17,795 human genomes HJ Abel, DE Larson, AA Regier, C Chiang, I Das, KL Kanchi, RM Layer, ... Nature 583 (7814), 83-89, 2020 | 229 | 2020 |
| A complete reference genome improves analysis of human genetic variation S Aganezov, SM Yan, DC Soto, M Kirsche, S Zarate, P Avdeyev, ... Science 376 (6588), eabl3533, 2022 | 228 | 2022 |
| MicroRNA-378 targets the myogenic repressor MyoR during myoblast differentiation J Gagan, BK Dey, R Layer, Z Yan, A Dutta Journal of Biological Chemistry 286 (22), 19431-19438, 2011 | 207 | 2011 |
| Breakpoint profiling of 64 cancer genomes reveals numerous complex rearrangements spawned by homology-independent mechanisms A Malhotra, M Lindberg, GG Faust, ML Leibowitz, RA Clark, RM Layer, ... Genome research 23 (5), 762-776, 2013 | 200 | 2013 |
| Vcfanno: fast, flexible annotation of genetic variants BS Pedersen, RM Layer, AR Quinlan Genome biology 17, 1-9, 2016 | 169 | 2016 |
| Combating subclonal evolution of resistant cancer phenotypes SW Brady, JA McQuerry, Y Qiao, SR Piccolo, G Shrestha, DF Jenkins, ... Nature communications 8 (1), 1231, 2017 | 148 | 2017 |
| GIGGLE: a search engine for large-scale integrated genome analysis RM Layer, BS Pedersen, T DiSera, GT Marth, J Gertz, AR Quinlan Nature methods 15 (2), 123-126, 2018 | 144 | 2018 |
| MUNC, a long noncoding RNA that facilitates the function of MyoD in skeletal myogenesis AC Mueller, MA Cichewicz, BK Dey, R Layer, BJ Reon, JR Gagan, A Dutta Molecular and cellular biology, 2015 | 135 | 2015 |
| Regulation of several androgen-induced genes through the repression of the miR-99a/let-7c/miR-125b-2 miRNA cluster in prostate cancer cells D Sun, R Layer, AC Mueller, MA Cichewicz, M Negishi, BM Paschal, ... Oncogene 33 (11), 1448-1457, 2014 | 112 | 2014 |
| Notch3 and Mef2c proteins are mutually antagonistic via Mkp1 protein and miR-1/206 microRNAs in differentiating myoblasts J Gagan, BK Dey, R Layer, Z Yan, A Dutta Journal of Biological Chemistry 287 (48), 40360-40370, 2012 | 109 | 2012 |
| The structural variation landscape in 492 Atlantic salmon genomes AC Bertolotti, RM Layer, MK Gundappa, MD Gallagher, E Pehlivanoglu, ... Nature Communications 11 (1), 5176, 2020 | 85 | 2020 |
| Whole-genome analysis for effective clinical diagnosis and gene discovery in early infantile epileptic encephalopathy BEP Ostrander, RJ Butterfield, BS Pedersen, AJ Farrell, RM Layer, ... NPJ genomic medicine 3 (1), 22, 2018 | 82 | 2018 |
| Samplot: a platform for structural variant visual validation and automated filtering JR Belyeu, M Chowdhury, J Brown, BS Pedersen, MJ Cormier, ... Genome biology 22 (1), 161, 2021 | 69 | 2021 |
| Efficient genotype compression and analysis of large genetic-variation data sets RM Layer, N Kindlon, KJ Karczewski, Exome Aggregation Consortium, ... Nature methods 13 (1), 63-65, 2016 | 63 | 2016 |
| Evaluating the risk of cyber attacks on SCADA systems via Petri net analysis with application to hazardous liquid loading operations MH Henry, RM Layer, KZ Snow, DR Zaret 2009 IEEE Conference on Technologies for Homeland Security, 607-614, 2009 | 50 | 2009 |
