| Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice FMS de Vrij, J Levenga, HC Van der Linde, SK Koekkoek, CI De Zeeuw, ... Neurobiology of disease 31 (1), 127-132, 2008 | 350 | 2008 |
| Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474 ACM van Esbroeck, APA Janssen, AB Cognetta, D Ogasawara, G Shpak, ... Science 356 (6342), 1084-1087, 2017 | 320 | 2017 |
| Mutant ubiquitin found in neurodegenerative disorders is a ubiquitin fusion degradation substrate that blocks proteasomal degradation K Lindsten, FMS de Vrij, LGGC Verhoef, DF Fischer, FW van Leeuwen, ... The Journal of cell biology 157 (3), 417-427, 2002 | 259 | 2002 |
| A simplified protocol for differentiation of electrophysiologically mature neuronal networks from human induced pluripotent stem cells N Gunhanlar, G Shpak, M Van Der Kroeg, LA Gouty-Colomer, ST Munshi, ... Molecular Psychiatry, 2017 | 220 | 2017 |
| The SAC1 domain in synaptojanin is required for autophagosome maturation at presynaptic terminals R Vanhauwaert, S Kuenen, R Masius, A Bademosi, J Manetsberger, ... The EMBO journal 36 (10), 1392-1411, 2017 | 195 | 2017 |
| Mutant ubiquitin expressed in Alzheimer’s disease causes neuronal death1 FMS De Vrij, JA Sluijs, L Gregori, DF Fischer, WT Hermens, D Goldgaber, ... The FASEB Journal 15 (14), 2680-2688, 2001 | 158 | 2001 |
| The neuroinvasiveness, neurotropism, and neurovirulence of SARS-CoV-2 L Bauer, BM Laksono, FMS de Vrij, SA Kushner, O Harschnitz, D van Riel Trends in Neurosciences, 2022 | 151 | 2022 |
| Disease-specific accumulation of mutant ubiquitin as a marker for proteasomal dysfunction in the brain DF FISCHER, ROBAI DE VOS, R VAN DIJK, FMS DE VRIJ, EA PROPER, ... The FASEB Journal 17 (14), 2014-2024, 2003 | 144 | 2003 |
| AFQ056, a new mGluR5 antagonist for treatment of fragile X syndrome J Levenga, S Hayashi, FMS de Vrij, SK Koekkoek, HC van der Linde, ... Neurobiology of disease 42 (3), 311-317, 2011 | 138 | 2011 |
| Hepatitis E virus infects neurons and brains X Zhou, F Huang, L Xu, Z Lin, F de Vrij, AC Ayo-Martin, M van der Kroeg, ... The Journal of Infectious Diseases 215 (8), 1197-1206, 2017 | 125 | 2017 |
| Potential therapeutic interventions for fragile X syndrome J Levenga, FMS de Vrij, BA Oostra, R Willemsen Trends in molecular medicine 16 (11), 516-527, 2010 | 111 | 2010 |
| Dose-dependent inhibition of proteasome activity by a mutant ubiquitin associated with neurodegenerative disease P van Tijn, FMS de Vrij, KG Schuurman, NP Dantuma, DF Fischer, ... Journal of cell science 120 (9), 1615-1623, 2007 | 107 | 2007 |
| SOX10 Single Transcription Factor-Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells JA García-León, M Kumar, R Boon, D Chau, E Wolfs, K Eggermont, ... Stem cell reports 10 (2), 655-672, 2018 | 105 | 2018 |
| Phenotypic differences between Asian and African lineage Zika viruses in human neural progenitor cells F Anfasa, JY Siegers, M van der Kroeg, N Mumtaz, VS Raj, FMS de Vrij, ... MSphere 2 (4), 2017 | 85 | 2017 |
| Loss of nuclear UBE3A causes electrophysiological and behavioral deficits in mice and is associated with Angelman syndrome R Avagliano Trezza, M Sonzogni, SNV Bossuyt, FI Zampeta, AM Punt, ... Nature Neuroscience, 2019 | 80 | 2019 |
| Novel genetic loci affecting facial shape variation in humans Z Xiong, G Dankova, LJ Howe, MK Lee, PG Hysi, MA de Jong, G Zhu, ... Elife 8, e49898, 2019 | 74 | 2019 |
| Novel genetic loci affecting facial shape variation in humans Z Xiong, G Dankova, LJ Howe, MK Lee, PG Hysi, MA de Jong, G Zhu, ... Elife 8, e49898, 2019 | 74 | 2019 |
| Candidate CSPG4 mutations and induced pluripotent stem cell modeling implicate oligodendrocyte progenitor cell dysfunction in familial schizophrenia FM de Vrij, CG Bouwkamp, N Gunhanlar, G Shpak, B Lendemeijer, ... Molecular psychiatry 24 (5), 757-771, 2019 | 66 | 2019 |
| Epigenetic characterization of the FMR1 promoter in induced pluripotent stem cells from human fibroblasts carrying an unmethylated full mutation CEF de Esch, M Ghazvini, F Loos, N Schelling-Kazaryan, W Widagdo, ... Stem cell reports 3 (4), 548-555, 2014 | 64 | 2014 |
| Subregion-specific dendritic spine abnormalities in the hippocampus of Fmr1 KO mice J Levenga, FMS de Vrij, RAM Buijsen, T Li, IM Nieuwenhuizen, A Pop, ... Neurobiology of learning and memory 95 (4), 467-472, 2011 | 64 | 2011 |
