Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy A Sanjuan-Pla, IC Macaulay, CT Jensen, PS Woll, TC Luis, A Mead, ... Nature 502 (7470), 232-236, 2013 | 697 | 2013 |
WNT signalling in the immune system: WNT is spreading its wings FJT Staal, TC Luis, MM Tiemessen Nature Reviews Immunology 8 (8), 581-593, 2008 | 685 | 2008 |
Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells J Carrelha, Y Meng, LM Kettyle, TC Luis, R Norfo, V Alcolea, ... Nature 554 (7690), 106-111, 2018 | 365 | 2018 |
Canonical wnt signaling regulates hematopoiesis in a dosage-dependent fashion TC Luis, BAE Naber, PPC Roozen, MH Brugman, EFE de Haas, ... Cell stem cell 9 (4), 345-356, 2011 | 364 | 2011 |
Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells A Grover, A Sanjuan-Pla, S Thongjuea, J Carrelha, A Giustacchini, ... Nature communications 7 (1), 11075, 2016 | 297 | 2016 |
Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells C Böiers, J Carrelha, M Lutteropp, S Luc, JCA Green, E Azzoni, PS Woll, ... Cell stem cell 13 (5), 535-548, 2013 | 296 | 2013 |
Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia development TC Luis, M Ichii, MH Brugman, P Kincade, FJT Staal Leukemia 26 (3), 414-421, 2012 | 243 | 2012 |
Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation TC Luis, F Weerkamp, BAE Naber, MRM Baert, EFE de Haas, T Nikolic, ... Blood, The Journal of the American Society of Hematology 113 (3), 546-554, 2009 | 243 | 2009 |
The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential S Luc, TC Luis, H Boukarabila, IC Macaulay, N Buza-Vidas, ... Nature immunology 13 (4), 412-419, 2012 | 171 | 2012 |
Wnt signaling in hematopoiesis: crucial factors for self‐renewal, proliferation, and cell fate decisions FJT Staal, TC Luis Journal of cellular biochemistry 109 (5), 844-849, 2010 | 113 | 2010 |
Identification of Notch target genes in uncommitted T-cell progenitors: No direct induction of a T-cell specific gene program F Weerkamp, TC Luis, BAE Naber, EEL Koster, L Jeannotte, ... Leukemia 20 (11), 1967-1977, 2006 | 85 | 2006 |
The evolving view of the hematopoietic stem cell niche I Beerman, TC Luis, S Singbrant, CL Celso, S Méndez-Ferrer Experimental hematology 50, 22-26, 2017 | 79 | 2017 |
A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors M Buono, R Facchini, S Matsuoka, S Thongjuea, D Waithe, TC Luis, ... Nature cell biology 18 (2), 157-167, 2016 | 75 | 2016 |
Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors TC Luis, S Luc, T Mizukami, H Boukarabila, S Thongjuea, PS Woll, ... Nature immunology 17 (12), 1424-1435, 2016 | 64 | 2016 |
In vivo labeling by CD73 marks multipotent stromal cells and highlights endothelial heterogeneity in the bone marrow niche M Breitbach, K Kimura, TC Luis, CJ Fuegemann, PS Woll, M Hesse, ... Cell Stem Cell 22 (2), 262-276. e7, 2018 | 63 | 2018 |
Signal transduction pathways regulating hematopoietic stem cell biology: introduction to a series of Spotlight Reviews TC Luis, N Killmann, FJT Staal Leukemia 26 (1), 86-90, 2012 | 55 | 2012 |
Wnt3a nonredundantly controls hematopoietic stem cell function and its deficiency results in complete absence of canonical Wnt signaling TC Luis, BAE Naber, WE Fibbe, JJM van Dongen, FJT Staal Blood, The Journal of the American Society of Hematology 116 (3), 496-497, 2010 | 54 | 2010 |
Manipulating niche composition limits damage to haematopoietic stem cells during Plasmodium infection MLR Haltalli, S Watcham, NK Wilson, K Eilers, A Lipien, H Ang, F Birch, ... Nature cell biology 22 (12), 1399-1410, 2020 | 30 | 2020 |
Biological implications of clonal hematopoiesis TC Luis, AC Wilkinson, I Beerman, S Jaiswal, LI Shlush Experimental hematology 77, 1-5, 2019 | 28 | 2019 |
WNT proteins: environmental factors regulating HSC fate in the niche TC Luis, FJT Staal Annals of the New York Academy of Sciences 1176 (1), 70-76, 2009 | 23 | 2009 |