Impaired allostimulatory capacity of peripheral blood dendritic cells recovered from hepatitis C virus-infected individuals T Kanto, N Hayashi, T Takehara, T Tatsumi, N Kuzushita, A Ito, Y Sasaki, ... The Journal of Immunology 162 (9), 5584-5591, 1999 | 452 | 1999 |
Circulating microRNA-21 as a novel biomarker for hepatocellular carcinoma Y Tomimaru, H Eguchi, H Nagano, H Wada, S Kobayashi, S Marubashi, ... Journal of hepatology 56 (1), 167-175, 2012 | 436 | 2012 |
Critical role of MHC class I-related chain A and B expression on IFN-α-stimulated dendritic cells in NK cell activation: impairment in chronic hepatitis C virus infection M Jinushi, T Takehara, T Kanto, T Tatsumi, V Groh, T Spies, T Miyagi, ... The Journal of Immunology 170 (3), 1249-1256, 2003 | 345 | 2003 |
Expression and role of MICA and MICB in human hepatocellular carcinomas and their regulation by retinoic acid M Jinushi, T Takehara, T Tatsumi, T Kanto, V Groh, T Spies, R Kimura, ... International journal of cancer 104 (3), 354-361, 2003 | 312 | 2003 |
Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma S Shimizu, T Takehara, H Hikita, T Kodama, H Tsunematsu, T Miyagi, ... International journal of cancer 131 (3), 548-557, 2012 | 306 | 2012 |
Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions in chronic hepatitis C virus … M Jinushi, T Takehara, T Tatsumi, T Kanto, T Miyagi, T Suzuki, ... The Journal of Immunology 173 (10), 6072-6081, 2004 | 292 | 2004 |
Reduced numbers and impaired ability of myeloid and plasmacytoid dendritic cells to polarize T helper cells in chronic hepatitis C virus infection T Kanto, M Inoue, H Miyatake, A Sato, M Sakakibara, T Yakushijin, C Oki, ... The Journal of infectious diseases 190 (11), 1919-1926, 2004 | 268 | 2004 |
A novel bulk-culture method for generating mature dendritic cells from mouse bone marrow cells YI Son, S Egawa, T Tatsumi, RE Redlinger Jr, P Kalinski, T Kanto Journal of immunological methods 262 (1-2), 145-157, 2002 | 252 | 2002 |
Hepatitis C virus nonstructural protein 5A modulates the toll-like receptor-MyD88-dependent signaling pathway in macrophage cell lines T Abe, Y Kaname, I Hamamoto, Y Tsuda, X Wen, S Taguwa, K Moriishi, ... Journal of virology 81 (17), 8953-8966, 2007 | 229 | 2007 |
Autocrine/paracrine IL-15 that is required for type I IFN-mediated dendritic cell expression of MHC class I-related chain A and B is impaired in hepatitis C virus infection M Jinushi, T Takehara, T Tatsumi, T Kanto, V Groh, T Spies, T Suzuki, ... The Journal of Immunology 171 (10), 5423-5429, 2003 | 207 | 2003 |
Influence of HLA haplotypes on the clinical courses of individuals infected with hepatitis C virus N Kuzushita, N Hayashi, T Moribe, K Katayama, T Kanto, S Nakatani, ... Hepatology 27 (1), 240-244, 1998 | 198 | 1998 |
Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice T Kodama, T Takehara, H Hikita, S Shimizu, M Shigekawa, H Tsunematsu, ... The Journal of clinical investigation 121 (8), 3343-3356, 2011 | 179 | 2011 |
The Bcl‐xL inhibitor, ABT‐737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib H Hikita, T Takehara, S Shimizu, T Kodama, M Shigekawa, K Iwase, ... Hepatology 52 (4), 1310-1321, 2010 | 161 | 2010 |
TIE2‐expressing monocytes as a diagnostic marker for hepatocellular carcinoma correlates with angiogenesis T Matsubara, T Kanto, S Kuroda, S Yoshio, K Higashitani, N Kakita, ... Hepatology 57 (4), 1416-1425, 2013 | 151 | 2013 |
Immunopathogenesis of hepatitis C virus infection: multifaceted strategies subverting innate and adaptive immunity T Kanto, N Hayashi Internal Medicine 45 (4), 183-191, 2006 | 146 | 2006 |
Buoyant density of hepatitis C virus recovered from infected hosts: two different features in sucrose equilibrium density-gradient centrifugation related to degree of liver … T Kanto, N Hayashi, T Takehara, H Hagiwara, E Mita, M Naito, ... Hepatology 19 (2), 296-302, 1994 | 142 | 1994 |
Expression of costimulatory molecules B7‐1 (CD80) and B7‐2 (CD86) on human hepatocellular carcinoma T Tatsumi, T Takehara, K Katayama, K Mochizuki, M Yamamoto, T Kanto, ... Hepatology 25 (5), 1108-1114, 1997 | 135 | 1997 |
Mcl‐1 and Bcl‐xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver H Hikita, T Takehara, S Shimizu, T Kodama, W Li, T Miyagi, A Hosui, ... Hepatology 50 (4), 1217-1226, 2009 | 128 | 2009 |
Human blood dendritic cell antigen 3 (BDCA3)+ dendritic cells are a potent producer of interferon‐λ in response to hepatitis C virus S Yoshio, T Kanto, S Kuroda, T Matsubara, K Higashitani, N Kakita, ... Hepatology 57 (5), 1705-1715, 2013 | 126 | 2013 |
Administration of interleukin-12 enhances the therapeutic efficacy of dendritic cell-based tumor vaccines in mouse hepatocellular carcinoma T Tatsumi, T Takehara, T Kanto, T Miyagi, N Kuzushita, Y Sugimoto, ... Cancer research 61 (20), 7563-7567, 2001 | 124 | 2001 |