| Arylfluorosulfates inactivate intracellular lipid binding protein (s) through chemoselective SuFEx reaction with a binding site Tyr residue W Chen, J Dong, L Plate, DE Mortenson, GJ Brighty, S Li, Y Liu, ... Journal of the American Chemical Society 138 (23), 7353-7364, 2016 | 246 | 2016 |
| Modulation of fluorescent protein chromophores to detect protein aggregation with turn-on fluorescence Y Liu, CH Wolstenholme, GC Carter, H Liu, H Hu, LS Grainger, K Miao, ... Journal of the American Chemical Society 140 (24), 7381-7384, 2018 | 179 | 2018 |
| A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans A Baranczak, Y Liu, S Connelly, WGH Du, ER Greiner, JC Genereux, ... Journal of the American Chemical Society 137 (23), 7404-7414, 2015 | 107 | 2015 |
| Aggfluor: fluorogenic toolbox enables direct visualization of the multi-step protein aggregation process in live cells CH Wolstenholme, H Hu, S Ye, BE Funk, D Jain, CH Hsiung, G Ning, ... Journal of the American Chemical Society 142 (41), 17515-17523, 2020 | 103 | 2020 |
| AgHalo: a facile fluorogenic sensor to detect drug‐induced proteome stress Y Liu, M Fares, NP Dunham, Z Gao, K Miao, X Jiang, SS Bollinger, ... Angewandte Chemie 129 (30), 8798-8802, 2017 | 92 | 2017 |
| Phosphorylation switches protein disulfide isomerase activity to maintain proteostasis and attenuate ER stress J Yu, T Li, Y Liu, X Wang, J Zhang, X Wang, G Shi, J Lou, L Wang, ... The EMBO journal 39 (10), e103841, 2020 | 83 | 2020 |
| The cation− π interaction enables a halo-tag fluorogenic probe for fast no-wash live cell imaging and gel-free protein quantification Y Liu, K Miao, NP Dunham, H Liu, M Fares, AK Boal, X Li, X Zhang Biochemistry 56 (11), 1585-1595, 2017 | 78 | 2017 |
| A solvatochromic fluorescent probe reveals polarity heterogeneity upon protein aggregation in cells W Wan, L Zeng, W Jin, X Chen, D Shen, Y Huang, M Wang, Y Bai, H Lyu, ... Angewandte Chemie 133 (49), 26069-26075, 2021 | 64 | 2021 |
| Synthesis of Sulfotyrosine‐Containing Peptides by Incorporating Fluorosulfated Tyrosine Using an Fmoc‐Based Solid‐Phase Strategy W Chen, J Dong, S Li, Y Liu, Y Wang, L Yoon, P Wu, KB Sharpless, ... Angewandte Chemie 128 (5), 1867-1870, 2016 | 58 | 2016 |
| Rational Design of Crystallization‐Induced‐Emission Probes To Detect Amorphous Protein Aggregation in Live Cells D Shen, W Jin, Y Bai, Y Huang, H Lyu, L Zeng, M Wang, Y Tang, W Wan, ... Angewandte Chemie 133 (29), 16203-16212, 2021 | 54 | 2021 |
| Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic Sequon W Chen, L Kong, S Connelly, JM Dendle, Y Liu, IA Wilson, ET Powers, ... ACS chemical biology 11 (7), 1852-1861, 2016 | 51 | 2016 |
| A Fluorogenic AggTag Method Based on Halo‐ and SNAP‐Tags to Simultaneously Detect Aggregation of Two Proteins in Live Cells KH Jung, SF Kim, Y Liu, X Zhang ChemBioChem 20 (8), 1078-1087, 2019 | 50 | 2019 |
| Individual and collective contributions of chaperoning and degradation to protein homeostasis in E. coli Y Cho, X Zhang, KFR Pobre, Y Liu, DL Powers, JW Kelly, LM Gierasch, ... Cell reports 11 (2), 321-333, 2015 | 49 | 2015 |
| A General Strategy to Enhance Donor‐Acceptor Molecules Using Solvent‐Excluding Substituents CA Hoelzel, H Hu, CH Wolstenholme, BA Karim, KT Munson, KH Jung, ... Angewandte Chemie 132 (12), 4815-4822, 2020 | 46 | 2020 |
| Monitoring the dynamics of proteome aggregation in live cells using a solubilized and noncovalent analogue of fluorescent protein chromophores W Wan, W Jin, Y Huang, Q Xia, Y Bai, H Lyu, D Liu, X Dong, W Li, Y Liu Analytical Chemistry 93 (3), 1717-1724, 2020 | 44 | 2020 |
| A HaloTag-based multicolor fluorogenic sensor visualizes and quantifies proteome stress in live cells using solvatochromic and molecular rotor-based fluorophores Y Liu, K Miao, Y Li, M Fares, S Chen, X Zhang Biochemistry 57 (31), 4663-4674, 2018 | 41 | 2018 |
| Design and application of fluorescent probes to detect cellular physical microenvironments J Ma, R Sun, K Xia, Q Xia, Y Liu, X Zhang Chemical Reviews 124 (4), 1738-1861, 2024 | 40 | 2024 |
| Stilbene vinyl sulfonamides as fluorogenic sensors of and traceless covalent kinetic stabilizers of transthyretin that prevent amyloidogenesis EH Suh, Y Liu, S Connelly, JC Genereux, IA Wilson, JW Kelly Journal of the American Chemical Society 135 (47), 17869-17880, 2013 | 39 | 2013 |
| Covalent probes for aggregated protein imaging via michael addition W Wan, Y Huang, Q Xia, Y Bai, Y Chen, W Jin, M Wang, D Shen, H Lyu, ... Angewandte Chemie International Edition 60 (20), 11335-11343, 2021 | 37 | 2021 |
| Fluorescence turn-on folding sensor to monitor proteome stress in live cells Y Liu, X Zhang, W Chen, YL Tan, JW Kelly Journal of the American Chemical Society 137 (35), 11303-11311, 2015 | 37 | 2015 |
