| Efficacy and safety of once-daily QVA149 compared with twice-daily salmeterol–fluticasone in patients with chronic obstructive pulmonary disease (ILLUMINATE): a randomised … CF Vogelmeier, ED Bateman, J Pallante, VKT Alagappan, P D'Andrea, ... The Lancet Respiratory Medicine 1 (1), 51-60, 2013 | 433 | 2013 |
| Efficacy and safety of NVA237 versus placebo and tiotropium in patients with COPD: the GLOW2 study E Kerwin, J Hébert, N Gallagher, C Martin, T Overend, VKT Alagappan, ... European Respiratory Journal 40 (5), 1106-1114, 2012 | 321 | 2012 |
| Efficacy and safety of intramuscular administration of tixagevimab–cilgavimab for early outpatient treatment of COVID-19 (TACKLE): a phase 3, randomised, double-blind, placebo … H Montgomery, FDR Hobbs, F Padilla, D Arbetter, A Templeton, ... The Lancet Respiratory Medicine 10 (10), 985-996, 2022 | 242 | 2022 |
| Enhanced bronchial expression of vascular endothelial growth factor and receptors (Flk-1 and Flt-1) in patients with chronic obstructive pulmonary disease AR Kranenburg, WI De Boer, VKT Alagappan, PJ Sterk, HS Sharma Thorax 60 (2), 106-113, 2005 | 211 | 2005 |
| Coordinated induction of iNOS–VEGF–KDR–eNOS after resveratrol consumption: A potential mechanism for resveratrol preconditioning of the heart S Das, VKT Alagappan, D Bagchi, HS Sharma, N Maulik, DK Das Vascular pharmacology 42 (5-6), 281-289, 2005 | 210 | 2005 |
| Dual bronchodilation with QVA149 reduces patient-reported dyspnoea in COPD: the BLAZE study DA Mahler, M Decramer, A D'Urzo, H Worth, T White, VKT Alagappan, ... European Respiratory Journal 43 (6), 1599-1609, 2014 | 205 | 2014 |
| Enhanced bronchial expression of extracellular matrix proteins in chronic obstructive pulmonary disease AR Kranenburg, A Willems-Widyastuti, WJ Mooi, PJ Sterk, ... American journal of clinical pathology 126 (5), 725-735, 2006 | 188 | 2006 |
| Role of extracellular matrix and its regulators in human airway smooth muscle biology K Parameswaran, A Willems-Widyastuti, VKT Alagappan, K Radford, ... Cell biochemistry and biophysics 44, 139-146, 2006 | 140 | 2006 |
| Effect of Roflumilast and Inhaled Corticosteroid/Long-Acting β2-Agonist on Chronic Obstructive Pulmonary Disease Exacerbations (RE2SPOND). A Randomized … FJ Martinez, KF Rabe, S Sethi, E Pizzichini, A McIvor, A Anzueto, ... American Journal of Respiratory and Critical Care Medicine 194 (5), 559-567, 2016 | 132 | 2016 |
| Safety and efficacy of dual bronchodilation with QVA149 in COPD patients: the ENLIGHTEN study R Dahl, KR Chapman, M Rudolf, R Mehta, P Kho, VKT Alagappan, ... Respiratory medicine 107 (10), 1558-1567, 2013 | 126 | 2013 |
| Efficacy and safety of QVA149 compared to the concurrent administration of its monocomponents indacaterol and glycopyrronium: the BEACON study R Dahl, D Jadayel, VKT Alagappan, H Chen, D Banerji International Journal of Chronic Obstructive Pulmonary Disease, 501-508, 2013 | 84 | 2013 |
| Effect of a single day of increased as-needed budesonide–formoterol use on short-term risk of severe exacerbations in patients with mild asthma: a post-hoc analysis of the … PM O'Byrne, JM FitzGerald, ED Bateman, PJ Barnes, J Zheng, ... The Lancet Respiratory Medicine 9 (2), 149-158, 2021 | 75 | 2021 |
| Determinants of response to roflumilast in severe chronic obstructive pulmonary disease. Pooled analysis of two randomized trials FJ Martinez, KF Rabe, PMA Calverley, LM Fabbri, S Sethi, E Pizzichini, ... American Journal of Respiratory and Critical Care Medicine 198 (10), 1268-1278, 2018 | 75 | 2018 |
| Angiogenesis and vascular remodeling in chronic airway diseases VKT Alagappan, WI de Boer, VK Misra, WJ Mooi, HS Sharma Cell biochemistry and biophysics 67, 219-234, 2013 | 66 | 2013 |
| Molecular mechanisms in chronic obstructive pulmonary disease: potential targets for therapy WI de Boer, VKT Alagappan, HS Sharma Cell biochemistry and biophysics 47, 131-147, 2007 | 63 | 2007 |
| Proinflammatory cytokines upregulate mRNA expression and secretion of vascular endothelial growth factor in cultured human airway smooth muscle cells VKT Alagappan, S McKay, A Widyastuti, IM Garrelds, A Bogers, ... Cell biochemistry and biophysics 43, 119-129, 2005 | 61 | 2005 |
| Anti-inflammatory effects of roflumilast in chronic obstructive pulmonary disease (ROBERT): a 16-week, randomised, placebo-controlled trial KF Rabe, H Watz, S Baraldo, F Pedersen, D Biondini, N Bagul, ... The Lancet Respiratory Medicine 6 (11), 827-836, 2018 | 51 | 2018 |
| A novel model-based approach for dose determination of glycopyrronium bromide in COPD H Arievich, T Overend, D Renard, M Gibbs, V Alagappan, M Looby, ... BMC Pulmonary Medicine 12, 1-12, 2012 | 38 | 2012 |
| Transforming growth factor-beta 1 induces angiogenesis in vitro via VEGF production in human airway smooth muscle cells A Willems-Widyastuti, VK Alagappan, U Arulmani, BM Vanaudenaerde, ... Indian journal of biochemistry and biophysics 48 (4), 262-269, 2011 | 35 | 2011 |
| Efficacy and safety of as-needed budesonide-formoterol in adolescents with mild asthma HK Reddel, PM O’Byrne, JM FitzGerald, PJ Barnes, J Zheng, S Ivanov, ... The Journal of Allergy and Clinical Immunology: In Practice 9 (8), 3069-3077. e6, 2021 | 34 | 2021 |
