关注
Chris Bakal
Chris Bakal
Team Leader, Chester Beatty Laboratories, Institute of Cancer Research
在 icr.ac.uk 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
The MAGUK family protein CARD11 is essential for lymphocyte activation
H Hara, T Wada, C Bakal, I Kozieradzki, S Suzuki, N Suzuki, M Nghiem, ...
Immunity 18 (6), 763-775, 2003
4042003
Quantitative morphological signatures define local signaling networks regulating cell morphology
C Bakal, J Aach, G Church, N Perrimon
science 316 (5832), 1753-1756, 2007
3852007
Genomic screening with RNAi: results and challenges
S Mohr, C Bakal, N Perrimon
Annual review of biochemistry 79 (1), 37-64, 2010
3532010
DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression
AR Barr, S Cooper, FS Heldt, F Butera, H Stoy, J Mansfeld, B Novák, ...
Nature communications 8 (1), 14728, 2017
3422017
Single-cell dynamics determines response to CDK4/6 inhibition in triple-negative breast cancer
US Asghar, AR Barr, R Cutts, M Beaney, I Babina, D Sampath, J Giltnane, ...
Clinical Cancer Research 23 (18), 5561-5572, 2017
2432017
A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes
Z Yin, A Sadok, H Sailem, A McCarthy, X Xia, F Li, MA Garcia, L Evans, ...
Nature cell biology 15 (7), 860-871, 2013
1972013
Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions
PM Müller, J Rademacher, RD Bagshaw, C Wortmann, C Barth, ...
Nature cell biology 22 (4), 498-511, 2020
1932020
Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death
H Okada, C Bakal, A Shahinian, A Elia, A Wakeham, WK Suh, GS Duncan, ...
The Journal of experimental medicine 199 (3), 399-410, 2004
1692004
Phosphorylation networks regulating JNK activity in diverse genetic backgrounds
C Bakal, R Linding, F Llense, E Heffern, E Martin-Blanco, T Pawson, ...
science 322 (5900), 453-456, 2008
1432008
Cell shape and the microenvironment regulate nuclear translocation of NF‐κB in breast epithelial and tumor cells
JE Sero, HZ Sailem, RC Ardy, H Almuttaqi, T Zhang, C Bakal
Molecular systems biology 11 (3), 790, 2015
1412015
Microenvironmental heterogeneity parallels breast cancer progression: a histology–genomic integration analysis
R Natrajan, H Sailem, FK Mardakheh, M Arias Garcia, CJ Tape, ...
PLoS medicine 13 (2), e1001961, 2016
1302016
A dynamical framework for the all-or-none G1/S transition
AR Barr, FS Heldt, T Zhang, C Bakal, B Novak
Cell systems 2 (1), 27-37, 2016
1192016
Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis
L Stojic, ATL Lun, J Mangei, P Mascalchi, V Quarantotti, AR Barr, C Bakal, ...
Nucleic acids research 46 (12), 5950-5966, 2018
1142018
Nanoneedle-mediated stimulation of cell mechanotransduction machinery
CS Hansel, SW Crowder, S Cooper, S Gopal, M João Pardelha da Cruz, ...
ACS nano 13 (3), 2913-2926, 2019
1132019
Mechanistic insight into the microtubule and actin cytoskeleton coupling through dynein-dependent RhoGEF inhibition
D Meiri, CB Marshall, MA Greeve, B Kim, M Balan, F Suarez, C Bakal, ...
Molecular cell 45 (5), 642-655, 2012
952012
A comprehensive model for the proliferation–quiescence decision in response to endogenous DNA damage in human cells
FS Heldt, AR Barr, S Cooper, C Bakal, B Novák
Proceedings of the National Academy of Sciences 115 (10), 2532-2537, 2018
822018
Multiparametric analysis of cell shape demonstrates that β-PIX directly couples YAP activation to extracellular matrix adhesion
JE Sero, C Bakal
Cell systems 4 (1), 84-96. e6, 2017
722017
Cross-talk between Rho and Rac GTPases drives deterministic exploration of cellular shape space and morphological heterogeneity
H Sailem, V Bousgouni, S Cooper, C Bakal
Open biology 4 (1), 130132, 2014
702014
The twin spot generator for differential Drosophila lineage analysis
R Griffin, A Sustar, M Bonvin, R Binari, A del Valle Rodriguez, AM Hohl, ...
Nature methods 6 (8), 600-602, 2009
642009
ALPK1 hotspot mutation as a driver of human spiradenoma and spiradenocarcinoma
M Rashid, M van der Horst, T Mentzel, F Butera, I Ferreira, A Pance, ...
Nature communications 10 (1), 2213, 2019
592019
系统目前无法执行此操作,请稍后再试。
文章 1–20