Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3536 | 2010 |
Endocytic mechanisms for targeted drug delivery LM Bareford, PW Swaan Advanced drug delivery reviews 59 (8), 748-758, 2007 | 1278 | 2007 |
Camptothecins: a review of their chemotherapeutic potential H Ulukan, PW Swaan Drugs 62 (14), 2039-2057, 2002 | 403 | 2002 |
Molecular basis of vitamin E action: tocotrienol modulates 12-lipoxygenase, a key mediator of glutamate-induced neurodegeneration S Khanna, S Roy, H Ryu, P Bahadduri, PW Swaan, RR Ratan, CK Sen Journal of Biological Chemistry 278 (44), 43508-43515, 2003 | 379 | 2003 |
Progress in predicting human ADME parameters in silico S Ekins, CL Waller, PW Swaan, G Cruciani, SA Wrighton, JH Wikel Journal of pharmacological and toxicological methods 44 (1), 251-272, 2000 | 376 | 2000 |
Surface acetylation of polyamidoamine (PAMAM) dendrimers decreases cytotoxicity while maintaining membrane permeability RB Kolhatkar, KM Kitchens, PW Swaan, H Ghandehari Bioconjugate chemistry 18 (6), 2054-2060, 2007 | 345 | 2007 |
Microfabricated porous silicon particles enhance paracellular delivery of insulin across intestinal Caco-2 cell monolayers AB Foraker, RJ Walczak, MH Cohen, TA Boiarski, CF Grove, PW Swaan Pharmaceutical research 20, 110-116, 2003 | 257 | 2003 |
Design, synthesis, cytoselective toxicity, structure–activity relationships, and pharmacophore of thiazolidinone derivatives targeting drug-resistant lung cancer cells H Zhou, S Wu, S Zhai, A Liu, Y Sun, R Li, Y Zhang, S Ekins, PW Swaan, ... Journal of Medicinal Chemistry 51 (5), 1242-1251, 2008 | 249 | 2008 |
ITC recommendations for transporter kinetic parameter estimation and translational modeling of transport‐mediated PK and DDIs in humans MJ Zamek‐Gliszczynski, CA Lee, A Poirier, J Bentz, X Chu, H Ellens, ... Clinical Pharmacology & Therapeutics 94 (1), 64-79, 2013 | 220 | 2013 |
Endocytosis and interaction of poly (amidoamine) dendrimers with Caco-2 cells KM Kitchens, AB Foraker, RB Kolhatkar, PW Swaan, H Ghandehari Pharmaceutical research 24, 2138-2145, 2007 | 218 | 2007 |
Transport of poly (amidoamine) dendrimers across Caco-2 cell monolayers: influence of size, charge and fluorescent labeling KM Kitchens, RB Kolhatkar, PW Swaan, ND Eddington, H Ghandehari Pharmaceutical research 23, 2818-2826, 2006 | 211 | 2006 |
The solute carrier family 10 (SLC10): beyond bile acid transport TC Da Silva, JE Polli, PW Swaan Molecular aspects of medicine 34 (2-3), 252-269, 2013 | 200 | 2013 |
Rapid identification of P-glycoprotein substrates and inhibitors C Chang, PM Bahadduri, JE Polli, PW Swaan, S Ekins Drug metabolism and disposition 34 (12), 1976-1984, 2006 | 186 | 2006 |
Endocytosis inhibitors prevent poly (amidoamine) dendrimer internalization and permeability across Caco-2 cells KM Kitchens, RB Kolhatkar, PW Swaan, H Ghandehari Molecular pharmaceutics 5 (2), 364-369, 2008 | 182 | 2008 |
Human pregnane X receptor antagonists and agonists define molecular requirements for different binding sites S Ekins, C Chang, S Mani, MD Krasowski, EJ Reschly, M Iyer, ... Molecular pharmacology 72 (3), 592-603, 2007 | 177 | 2007 |
Microfluidic preparation of liposomes to determine particle size influence on cellular uptake mechanisms AU Andar, RR Hood, WN Vreeland, DL DeVoe, PW Swaan Pharmaceutical research 31, 401-413, 2014 | 174 | 2014 |
Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4 K Köck, BC Ferslew, I Netterberg, K Yang, TJ Urban, PW Swaan, ... Drug metabolism and disposition 42 (4), 665-674, 2014 | 170 | 2014 |
Post-translational modifications of transporters LC Czuba, KM Hillgren, PW Swaan Pharmacology & therapeutics 192, 88-99, 2018 | 148 | 2018 |
Current perspectives on the cellular uptake and trafficking of riboflavin AB Foraker, CM Khantwal, PW Swaan Advanced drug delivery reviews 55 (11), 1467-1483, 2003 | 147 | 2003 |
Structural determinants of P-glycoprotein-mediated transport of glucocorticoids CR Yates, C Chang, JD Kearbey, K Yasuda, EG Schuetz, DD Miller, ... Pharmaceutical research 20, 1794-1803, 2003 | 146 | 2003 |