Self-propagation of pathogenic protein aggregates in neurodegenerative diseases M Jucker, LC Walker Nature 501 (7465), 45-51, 2013 | 1769 | 2013 |
Exogenous induction of cerebral β-amyloidogenesis is governed by agent and host M Meyer-Luehmann, J Coomaraswamy, T Bolmont, S Kaeser, C Schaefer, ... Science 313 (5794), 1781-1784, 2006 | 1127 | 2006 |
Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders M Jucker, LC Walker Annals of neurology 70 (4), 532-540, 2011 | 732 | 2011 |
Peripherally applied Aβ-containing inoculates induce cerebral β-amyloidosis YS Eisele, U Obermüller, G Heilbronner, F Baumann, SA Kaeser, ... Science 330 (6006), 980-982, 2010 | 664 | 2010 |
Evidence for seeding of β-amyloid by intracerebral infusion of Alzheimer brain extracts in β-amyloid precursor protein-transgenic mice MD Kane, WJ Lipinski, MJ Callahan, F Bian, RA Durham, RD Schwarz, ... Journal of Neuroscience 20 (10), 3606-3611, 2000 | 476 | 2000 |
Deposition of Alzheimer's β-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans S Vogelgesang, I Cascorbi, E Schroeder, J Pahnke, HK Kroemer, ... Pharmacogenetics and Genomics 12 (7), 535-541, 2002 | 442 | 2002 |
Neurodegenerative diseases: expanding the prion concept LC Walker, M Jucker Annual review of neuroscience 38 (1), 87-103, 2015 | 380 | 2015 |
Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases M Jucker, LC Walker Nature neuroscience 21 (10), 1341-1349, 2018 | 373 | 2018 |
Age‐dependent impairment of mitochondrial function in primate brain AC Bowling, EM Mutisya, LC Walker, DL Price, LC Cork, MH Beal Journal of neurochemistry 60 (5), 1964-1967, 1993 | 354 | 1993 |
Induction of cerebral β-amyloidosis: intracerebral versus systemic Aβ inoculation YS Eisele, T Bolmont, M Heikenwalder, F Langer, LH Jacobson, ZX Yan, ... Proceedings of the National Academy of Sciences 106 (31), 12926-12931, 2009 | 326 | 2009 |
Augmented senile plaque load in aged female β-amyloid precursor protein-transgenic mice MJ Callahan, WJ Lipinski, F Bian, RA Durham, A Pack, LC Walker The American journal of pathology 158 (3), 1173-1177, 2001 | 320 | 2001 |
Aged monkeys exhibit behavioral deficits indicative of widespread cerebral dysfunction J Bachevalier, LS Landis, LC Walker, M Brickson, M Mishkin, DL Price, ... Neurobiology of aging 12 (2), 99-111, 1991 | 311 | 1991 |
Accelerated glial reactivity to stroke in aged rats correlates with reduced functional recovery I Badan, B Buchhold, A Hamm, M Gratz, LC Walker, D Platt, C Kessler, ... Journal of Cerebral Blood Flow & Metabolism 23 (7), 845-854, 2003 | 307 | 2003 |
MDR1‐P‐Glycoprotein (ABCB1) Mediates Transport of Alzheimer’s Amyloid‐β Peptides—Implications for the Mechanisms of Aβ Clearance at the Blood–Brain Barrier D Kuhnke, G Jedlitschky, M Grube, M Krohn, M Jucker, I Mosyagin, ... Brain Pathology 17 (4), 347-353, 2007 | 294 | 2007 |
Loss of NMDA, but not GABA-A, binding in the brains of aged rats and monkeys GL Wenk, LC Walker, DL Price, LC Cork Neurobiology of aging 12 (2), 93-98, 1991 | 294 | 1991 |
Mechanisms of protein seeding in neurodegenerative diseases LC Walker, MI Diamond, KE Duff, BT Hyman JAMA neurology 70 (3), 304-310, 2013 | 281 | 2013 |
Soluble Aβ seeds are potent inducers of cerebral β-amyloid deposition F Langer, YS Eisele, SK Fritschi, M Staufenbiel, LC Walker, M Jucker Journal of Neuroscience 31 (41), 14488-14495, 2011 | 276 | 2011 |
Amyloid-associated neuron loss and gliogenesis in the neocortex of amyloid precursor protein transgenic mice L Bondolfi, M Calhoun, F Ermini, HG Kuhn, KH Wiederhold, L Walker, ... Journal of Neuroscience 22 (2), 515-522, 2002 | 264 | 2002 |
Abnormalities of the nucleus basalis in Down's syndrome MF Casanova, LC Walker, PJ Whitehouse, DL Price Annals of Neurology: Official Journal of the American Neurological …, 1985 | 249 | 1985 |
Loss of pedunculopontine neurons in progressive supranuclear palsy RM Zweig, PJ Whitehouse, MF Casanova, LC Walker, WR Jankel, ... Annals of neurology 22 (1), 18-25, 1987 | 223 | 1987 |