| Integrating cellular metabolism into a multiscale whole-body model M Krauss, S Schaller, S Borchers, R Findeisen, J Lippert, L Kuepfer PLoS computational biology 8 (10), e1002750, 2012 | 139 | 2012 |
| A generic integrated physiologically based whole‐body model of the glucose‐insulin‐glucagon regulatory system S Schaller, S Willmann, J Lippert, L Schaupp, TR Pieber, A Schuppert, ... CPT: pharmacometrics & systems pharmacology 2 (8), 1-10, 2013 | 85 | 2013 |
| Open systems pharmacology community—an open access, open source, open science approach to modeling and simulation in pharmaceutical sciences J Lippert, R Burghaus, A Edginton, S Frechen, M Karlsson, A Kovar, ... CPT: pharmacometrics & systems pharmacology 8 (12), 878, 2019 | 79 | 2019 |
| Safer chemicals using less animals: kick-off of the European ONTOX project M Vinken, E Benfenati, F Busquet, J Castell, DA Clevert, TM de Kok, ... Toxicology 458, 152846, 2021 | 45 | 2021 |
| Robust PBPK/PD-based model predictive control of blood glucose S Schaller, J Lippert, L Schaupp, TR Pieber, A Schuppert, T Eissing IEEE Transactions on Biomedical Engineering 63 (7), 1492-1504, 2015 | 32 | 2015 |
| A quantitative systems pharmacology kidney model of diabetes associated renal hyperfiltration and the effects of SGLT inhibitors P Balazki, S Schaller, T Eissing, T Lehr CPT: pharmacometrics & systems pharmacology 7 (12), 788-797, 2018 | 23 | 2018 |
| Physiologically based simulations of deuterated glucose for quantifying cell turnover in humans J Lahoz-Beneytez, S Schaller, D Macallan, T Eissing, C Niederalt, ... Frontiers in immunology 8, 252675, 2017 | 14 | 2017 |
| A generic avian physiologically-based kinetic (PBK) model and its application in three bird species V Baier, A Paini, S Schaller, CG Scanes, AJ Bone, M Ebeling, TG Preuss, ... Environment International 169, 107547, 2022 | 13 | 2022 |
| A multiscale, model-based analysis of the multi-tissue interplay underlying blood glucose regulation in type I diabetes F Wadehn, S Schaller, T Eissing, M Krauss, L Küpfer 2016 38th Annual International Conference of the IEEE Engineering in …, 2016 | 12 | 2016 |
| Quantitative comparison of avian and mammalian physiologies for parameterization of physiologically based kinetic models CG Scanes, J Witt, M Ebeling, S Schaller, V Baier, AJ Bone, TG Preuss, ... Frontiers in physiology 13, 858386, 2022 | 11 | 2022 |
| Modeling and simulation of in vivo drug effects J Lippert, R Burghaus, L Kuepfer, B Ploeger, S Schaller, W Schmitt, ... New Approaches to Drug Discovery, 313-329, 2016 | 8 | 2016 |
| Human recessive osteopetrosis M Helfrich, B Perdu, F Coxon Osteologie 18 (04), 260-267, 2009 | 7 | 2009 |
| A Physiologically‐Based Quantitative Systems Pharmacology Model of the Incretin Hormones GLP‐1 and GIP and the DPP4 Inhibitor Sitagliptin P Balazki, S Schaller, T Eissing, T Lehr CPT: pharmacometrics & systems pharmacology 9 (6), 353-362, 2020 | 5 | 2020 |
| Considering developmental neurotoxicity in vitro data for human health risk assessment using physiologically-based kinetic modeling: deltamethrin case study C Maass, S Schaller, A Dallmann, K Bothe, D Müller Toxicological Sciences 192 (1), 59-70, 2023 | 4 | 2023 |
| Quantitative morphometric, physiological, and metabolic characteristics of chickens and mallards for physiologically based kinetic model development CG Scanes, J Witt, M Ebeling, S Schaller, V Baier, AJ Bone, TG Preuss, ... Frontiers in Physiology 13, 858283, 2022 | 4 | 2022 |
| Automated optimal glycaemic control using a physiology based pharmacokinetic, pharmacodynamic model S Schaller Aachen, Techn. Hochsch., Diss., 2014, 2015 | 4 | 2015 |
| Evaluation of the drug‐drug interaction potential of treosulfan using a physiologically‐based pharmacokinetic modelling approach S Schaller, FS Martins, P Balazki, S Böhm, J Baumgart, RA Hilger, ... British Journal of Clinical Pharmacology 88 (4), 1722-1734, 2022 | 3 | 2022 |
| A new Perspective on Closed-Loop Glucose Control using a Physiology-Based Pharmacokinetic/Pharmacodynamic Model Kernel S Schaller, S Willmann, L Schaupp, T Pieber, A Schuppert, J Lippert, ... IFAC Proceedings Volumes 45 (18), 420-425, 2012 | 3 | 2012 |
| Integration of artificial neural network and physiologically based biopharmaceutic models in the development of sustained‐release formulations F Severino Martins, L Borges, R Oliveira do Couto, S Schaller, ... Biopharmaceutics & Drug Disposition 44 (4), 335-343, 2023 | 1 | 2023 |
| Systematic evaluation of high-throughput PBK modelling strategies for the prediction of intravenous and oral pharmacokinetics in humans R Geci, D Gadaleta, MG de Lomana, R Ortega-Vallbona, E Colombo, ... Archives of Toxicology, 1-18, 2024 | | 2024 |
Thomas EissingBayer AG在 bayer.com 的电子邮件经过验证
