Rho and Rac take center stage K Burridge, K Wennerberg Cell 116 (2), 167-179, 2004 | 2339 | 2004 |
The Ras superfamily at a glance K Wennerberg, KL Rossman, CJ Der Journal of cell science 118 (5), 843-846, 2005 | 2068 | 2005 |
Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia HLM Koskela, S Eldfors, P Ellonen, AJ van Adrichem, H Kuusanmäki, ... New England journal of medicine 366 (20), 1905-1913, 2012 | 862 | 2012 |
Rho-family GTPases: it's not only Rac and Rho (and I like it) K Wennerberg, CJ Der Journal of cell science 117 (8), 1301-1312, 2004 | 854 | 2004 |
A community effort to assess and improve drug sensitivity prediction algorithms JC Costello, LM Heiser, E Georgii, M Gönen, MP Menden, NJ Wang, ... Nature biotechnology 32 (12), 1202-1212, 2014 | 772 | 2014 |
Integrin signaling to the actin cytoskeleton KA DeMali, K Wennerberg, K Burridge Current opinion in cell biology 15 (5), 572-582, 2003 | 672 | 2003 |
Searching for drug synergy in complex dose–response landscapes using an interaction potency model B Yadav, K Wennerberg, T Aittokallio, J Tang Computational and structural biotechnology journal 13, 504-513, 2015 | 617 | 2015 |
Polymerization of type I and III collagens is dependent on fibronectin and enhanced by integrins α11β1and α2β1 T Velling, J Risteli, K Wennerberg, DF Mosher, S Johansson Journal of Biological Chemistry 277 (40), 37377-37381, 2002 | 475 | 2002 |
Fibronectin-integrin interactions S Johansson, G Svineng, K Wennerberg, A Armulik, L Lohikangas Front Biosci 2 (4), d126-d146, 1997 | 455 | 1997 |
Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia T Pemovska, M Kontro, B Yadav, H Edgren, S Eldfors, A Szwajda, ... Cancer discovery 3 (12), 1416-1429, 2013 | 449* | 2013 |
Making sense of large-scale kinase inhibitor bioactivity data sets: a comparative and integrative analysis J Tang, A Szwajda, S Shakyawar, T Xu, P Hintsanen, K Wennerberg, ... Journal of Chemical Information and Modeling 54 (3), 735-743, 2014 | 412 | 2014 |
Serine phosphorylation negatively regulates RhoA in vivo SM Ellerbroek, K Wennerberg, K Burridge Journal of Biological Chemistry 278 (21), 19023-19031, 2003 | 391 | 2003 |
Network pharmacology applications to map the unexplored target space and therapeutic potential of natural products M Kibble, N Saarinen, J Tang, K Wennerberg, S Mäkelä, T Aittokallio Natural product reports 32 (8), 1249-1266, 2015 | 385 | 2015 |
Beta 1 integrin-dependent and-independent polymerization of fibronectin. K Wennerberg, L Lohikangas, D Gullberg, M Pfaff, S Johansson, ... The Journal of cell biology 132 (1), 227-238, 1996 | 376 | 1996 |
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia HLM Rajala, S Eldfors, H Kuusanmäki, AJ Van Adrichem, T Olson, ... Blood, The Journal of the American Society of Hematology 121 (22), 4541-4550, 2013 | 330 | 2013 |
Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies B Yadav, T Pemovska, A Szwajda, E Kulesskiy, M Kontro, R Karjalainen, ... Scientific reports 4 (1), 1-10, 2014 | 322 | 2014 |
Rnd proteins function as RhoA antagonists by activating p190 RhoGAP K Wennerberg, MA Forget, SM Ellerbroek, WT Arthur, K Burridge, ... Current Biology 13 (13), 1106-1115, 2003 | 302 | 2003 |
Axitinib effectively inhibits BCR-ABL1 (T315I) with a distinct binding conformation T Pemovska, E Johnson, M Kontro, GA Repasky, J Chen, P Wells, ... Nature 519 (7541), 102-105, 2015 | 267 | 2015 |
Long-term ERK inhibition in KRAS-mutant pancreatic cancer is associated with MYC degradation and senescence-like growth suppression TK Hayes, NF Neel, C Hu, P Gautam, M Chenard, B Long, M Aziz, ... Cancer cell 29 (1), 75-89, 2016 | 236 | 2016 |
Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses FS Varghese, P Kaukinen, S Gläsker, M Bespalov, L Hanski, ... Antiviral research 126, 117-124, 2016 | 229 | 2016 |