Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics I Irrcher, H Aleyasin, EL Seifert, SJ Hewitt, S Chhabra, M Phillips, AK Lutz, ... Human molecular genetics 19 (19), 3734-3746, 2010 | 458 | 2010 |
Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage N Arbour, JL Vanderluit, JN Le Grand, A Jahani-Asl, VA Ruzhynsky, ... Journal of Neuroscience 28 (24), 6068-6078, 2008 | 229 | 2008 |
Mitofusin 2 protects cerebellar granule neurons against injury-induced cell death A Jahani-Asl, ECC Cheung, M Neuspiel, JG MacLaurin, A Fortin, DS Park, ... Journal of Biological Chemistry 282 (33), 23788-23798, 2007 | 229 | 2007 |
Chemoresistance in human ovarian cancer: the role of apoptotic regulators M Fraser, B Leung, A Jahani-Asl, X Yan, WE Thompson, BK Tsang Reproductive biology and endocrinology 1, 1-13, 2003 | 220 | 2003 |
Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis VD Soleimani, H Yin, A Jahani-Asl, H Ming, CEM Kockx, WFJ van Ijcken, ... Molecular cell 47 (3), 457-468, 2012 | 202 | 2012 |
The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity A Jahani-Asl, K Pilon-Larose, W Xu, JG MacLaurin, DS Park, HM McBride, ... Journal of Biological Chemistry 286 (6), 4772-4782, 2011 | 129 | 2011 |
The phosphorylation state of Drp1 determines cell fate A Jahani‐Asl, RS Slack EMBO reports 8 (10), 912-913, 2007 | 108 | 2007 |
The X-linked intellectual disability protein PHF6 associates with the PAF1 complex and regulates neuronal migration in the mammalian brain C Zhang, LA Mejia, J Huang, P Valnegri, EJ Bennett, J Anckar, ... Neuron 78 (6), 986-993, 2013 | 105 | 2013 |
Control of glioblastoma tumorigenesis by feed-forward cytokine signaling A Jahani-Asl, H Yin, VD Soleimani, T Haque, HA Luchman, NC Chang, ... Nature neuroscience 19 (6), 798-806, 2016 | 103 | 2016 |
CDK5 phosphorylates DRP1 and drives mitochondrial defects in NMDA-induced neuronal death A Jahani-Asl, E Huang, I Irrcher, J Rashidian, N Ishihara, DC Lagace, ... Human molecular genetics 24 (16), 4573-4583, 2015 | 89 | 2015 |
iNOS: a potential therapeutic target for malignant glioma A Jahani-Asl, A Bonni Current molecular medicine 13 (8), 1241-1249, 2013 | 74 | 2013 |
OSMR controls glioma stem cell respiration and confers resistance of glioblastoma to ionizing radiation A Sharanek, A Burban, M Laaper, E Heckel, JS Joyal, VD Soleimani, ... Nature communications 11 (1), 4116, 2020 | 56 | 2020 |
STAT3-iNOS signaling mediates EGFRvIII-induced glial proliferation and transformation SV Puram, CM Yeung, A Jahani-Asl, C Lin, N de la Iglesia, G Konopka, ... Journal of Neuroscience 32 (23), 7806-7818, 2012 | 54 | 2012 |
Myf6/MRF4 is a myogenic niche regulator required for the maintenance of the muscle stem cell pool F Lazure, DM Blackburn, AH Corchado, K Sahinyan, N Karam, ... EMBO reports 21 (12), e49499, 2020 | 51 | 2020 |
Mitochondria: joining forces to thwart cell death A Jahani-Asl, M Germain, RS Slack Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1802 (1), 162-166, 2010 | 45 | 2010 |
Pathogenesis of Börjeson-Forssman-Lehmann syndrome: insights from PHF6 function A Jahani-Asl, C Cheng, C Zhang, A Bonni Neurobiology of disease 96, 227-235, 2016 | 34 | 2016 |
Caspase-3-mediated cleavage of Akt: involvement of non-consensus sites and influence of phosphorylation A Jahani-Asl, A Basak, BK Tsang FEBS letters 581 (16), 2883-2888, 2007 | 30 | 2007 |
Characterization of a mouse model of Börjeson-Forssman-Lehmann syndrome C Cheng, PY Deng, Y Ikeuchi, C Yuede, D Li, N Rensing, J Huang, ... Cell reports 25 (6), 1404-1414. e6, 2018 | 23 | 2018 |
Transcriptional reprogramming of skeletal muscle stem cells by the niche environment F Lazure, R Farouni, K Sahinyan, DM Blackburn, A Hernández-Corchado, ... Nature Communications 14 (1), 535, 2023 | 21 | 2023 |
Transcriptional control of brain tumor stem cells by a carbohydrate binding protein A Sharanek, A Burban, A Hernandez-Corchado, A Madrigal, ... Cell reports 36 (9), 2021 | 20 | 2021 |