Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation CS Schneider, Q Xu, NJ Boylan, J Chisholm, BC Tang, BS Schuster, ... Science advances 3 (4), e1601556, 2017 | 272 | 2017 |
Animal models of human prostate cancer: the consensus report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee M Ittmann, J Huang, E Radaelli, P Martin, S Signoretti, R Sullivan, ... Cancer research 73 (9), 2718-2736, 2013 | 260 | 2013 |
Activation of canonical WNT/β-catenin signaling enhances in vitro motility of glioblastoma cells by activation of ZEB1 and other activators of epithelial-to … UD Kahlert, D Maciaczyk, S Doostkam, BA Orr, B Simons, T Bogiel, ... Cancer letters 325 (1), 42-53, 2012 | 255 | 2012 |
Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer EM Schaeffer, L Marchionni, Z Huang, B Simons, A Blackman, W Yu, ... Oncogene 27 (57), 7180-7191, 2008 | 199 | 2008 |
Targeting the EMT transcription factor TWIST1 overcomes resistance to EGFR inhibitors in EGFR-mutant non-small-cell lung cancer ZA Yochum, J Cades, H Wang, S Chatterjee, BW Simons, JP O’Brien, ... Oncogene 38 (5), 656-670, 2019 | 165 | 2019 |
Correlation of B7-H3 with androgen receptor, immune pathways and poor outcome in prostate cancer: an expression-based analysis B Benzon, SG Zhao, MC Haffner, M Takhar, N Erho, K Yousefi, P Hurley, ... Prostate cancer and prostatic diseases 20 (1), 28-35, 2017 | 145 | 2017 |
Nanoparticle interactions with immune cells dominate tumor retention and induce T cell–mediated tumor suppression in models of breast cancer P Korangath, JD Barnett, A Sharma, ET Henderson, J Stewart, SH Yu, ... Science Advances 6 (13), eaay1601, 2020 | 134 | 2020 |
An EGFR-ERK-SOX9 signaling cascade links urothelial development and regeneration to cancer S Ling, X Chang, L Schultz, TK Lee, A Chaux, L Marchionni, GJ Netto, ... Cancer research 71 (11), 3812-3821, 2011 | 128 | 2011 |
TWIST1-WDR5-Hottip Regulates Hoxa9 Chromatin to Facilitate Prostate Cancer Metastasis R Malek, RP Gajula, RD Williams, B Nghiem, BW Simons, K Nugent, ... Cancer research 77 (12), 3181-3193, 2017 | 122 | 2017 |
Notch signaling in prostate cancer: a moving target FLF Carvalho, BW Simons, CG Eberhart, DM Berman The Prostate 74 (9), 933-945, 2014 | 116 | 2014 |
Vaginal delivery of paclitaxel via nanoparticles with non‐mucoadhesive surfaces suppresses cervical tumor growth M Yang, T Yu, YY Wang, SK Lai, Q Zeng, B Miao, BC Tang, BW Simons, ... Advanced healthcare materials 3 (7), 1044-1052, 2014 | 111 | 2014 |
Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells JE Ohm, P Mali, L Van Neste, DM Berman, L Liang, K Pandiyan, ... Cancer research 70 (19), 7662-7673, 2010 | 99 | 2010 |
A human prostatic bacterial isolate alters the prostatic microenvironment and accelerates prostate cancer progression BW Simons, NM Durham, TC Bruno, JF Grosso, AJ Schaeffer, AE Ross, ... The Journal of pathology 235 (3), 478-489, 2015 | 87 | 2015 |
Sox9 is required for prostate development and prostate cancer initiation Z Huang, PJ Hurley, BW Simons, L Marchionni, DM Berman, AE Ross, ... Oncotarget 3 (6), 651, 2012 | 66 | 2012 |
O-GlcNAcylation is required for mutant KRAS-induced lung tumorigenesis K Taparra, H Wang, R Malek, A Lafargue, MA Barbhuiya, X Wang, ... The Journal of clinical investigation 128 (11), 4924-4937, 2019 | 64 | 2019 |
Secreted protein, acidic and rich in cysteine-like 1 (SPARCL1) is down regulated in aggressive prostate cancers and is prognostic for poor clinical outcome PJ Hurley, L Marchionni, BW Simons, AE Ross, SB Peskoe, RM Miller, ... Proceedings of the National Academy of Sciences 109 (37), 14977-14982, 2012 | 63 | 2012 |
Enhancement of airway gene transfer by DNA nanoparticles using a pH-responsive block copolymer of polyethylene glycol and poly-L-lysine NJ Boylan, AJ Kim, JS Suk, P Adstamongkonkul, BW Simons, SK Lai, ... Biomaterials 33 (7), 2361-2371, 2012 | 62 | 2012 |
Wnt signaling though beta-catenin is required for prostate lineage specification BW Simons, PJ Hurley, Z Huang, AE Ross, R Miller, L Marchionni, ... Developmental biology 371 (2), 246-255, 2012 | 60 | 2012 |
A potential tumor suppressor role for Hic1 in breast cancer through transcriptional repression of ephrin-A1 W Zhang, X Zeng, KJ Briggs, R Beaty, B Simons, RW Chiu Yen, MA Tyler, ... Oncogene 29 (17), 2467-2476, 2010 | 58 | 2010 |
Asporin restricts mesenchymal stromal cell differentiation, alters the tumor microenvironment, and drives metastatic progression RM Hughes, BW Simons, H Khan, R Miller, V Kugler, S Torquato, ... Cancer research 79 (14), 3636-3650, 2019 | 56 | 2019 |